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Engineered Telodendrimer Nanocarriers for Monomeric Amphotericin B Delivery

A nanocarrier platform for Amphotericin B that improves efficacy and reduces cost, while decreasing toxicity. Background: Systemic fungal infections are an increasingly prevalent health problem. The hydrophobic polyene antibiotic Amphotericin B (AmB) is the drug of choice for these life-threatening invasive fungal infections. Unfortunately, it produces...

Published: 4/1/2025 | Inventor(s): Juntao Luo, Xiaotian Ji, Changying Shi

Keywords(s): Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics and Vaccines

Suspended Graphene Energy Harvesting Solid State Structure

An energy harvesting device made possible by the oscillatory behavior of suspending graphene. Background: Even low power devices need consistent, reliable energy sources that in most cases must be powered indefinitely in order to accomplish the device’s objectives. Maintaining a secure and independent energy source for powering small, sometimes...

Published: 4/1/2025 | Inventor(s): Nicholas Pieniazek, Christopher Hobbs, Vincent LaBella

Keywords(s): battery systems, circuit design, energy storage devices, material science, microsystem, nanoengineering, nanofabrication, nanotechnology, semiconductors, Technologies

Category(s): Technology Classifications > Energy, Technology Classifications > Environment, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Campus > SUNY Polytechnic Institute, Campus > NY CREATES

A Nanotrap to Improve Survival in Severe Sepsis by Attenuating Hyperinflammation Through Hemoperfusion

This optimized nanotrap therapy in combination with a moderate antibiotic treatment resulted in a 100% survival rate in severe septic mice. Background: The mortality rates in severe sepsis patients are 30‑41%. In the U.S. alone, 1.7 million people develop sepsis on a yearly basis. Effective therapies to prevent or treat the cytokine storm or septic...

Published: 4/1/2025 | Inventor(s): Juntao Luo, Lili Wang, Changying Shi

Keywords(s):

Category(s): Campus > Upstate Medical University, Technology Classifications > Nanotechnology

Improved Chemical-Mechanical Polishing Slurry Composition and Method to Improve Polishing of Metals and Non-metals Using Cerium Oxide Nanoparticles

Reducing manufacturing time, cost, and labor by employing chemistry to transform a two-step process into an easily controlled single-step. Background: Integrated circuits are built of many layers. Each layer must be perfectly flat so that connections line up between layers and electricity flows properly throughout. Conventional CMP systems consist...

Published: 4/1/2025 | Inventor(s): Christopher Netzband, Kathleen Dunn

Keywords(s): abrasive, cerium, cerium oxide, chemical activity, chemical mechanical polishing, CMP, CMP slurries, dielectrics, fiber optics, integrated circuit, lens, mechanical polish, metallic surface, optics, polish, polishing, semiconductor wafers, semiconductors, slurry, surface finishing, surface quality

Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology

Deuterized Low-K Dielectric Materials for TDDB Mitigation

Simple, scalable and inexpensive process to replace the hydrogen in low-k dielectrics with deuterium to improve semiconductor performance. Background: Low-k dielectrics are a class of materials used in the manufacture of nanoscale semiconductor devices. The problem with low-k dielectrics is that they are susceptible to a phenomenon known as time dependent...

Published: 4/3/2025 | Inventor(s): James Lloyd, Niaz Mahmud

Keywords(s): nanotechnology, semiconductors

Category(s): Technology Classifications > Nanotechnology, Campus > SUNY Polytechnic Institute

System and Methods for Detecting, Capturing, and Measuring Nanoparticles

Speeds the semiconductor manufacturing process by detecting particles smaller than 20nm before they have adhered to the silicon wafer. Background: The conventional method for of detecting particles during the semiconductor manufacturing process occurs only after the particles have adhered to silicon wafer. While that approach is easier because...

Published: 4/1/2025 | Inventor(s): Gregory Denbeaux, Yashdeep Khopkar

Keywords(s): defect-tolerant semiconductor, Technologies

Category(s): Technology Classifications > Nanotechnology, Campus, Campus > SUNY Polytechnic Institute

Polymeric Micro-Cantilevers for Ultra-Low Volume Fluid and Living Cell Deposition

Improves upon existing grooved cantilever designs by creating cantilevers from polymeric materials. Background: Microcantilevers have been used for a variety of nano and microscale printing techniques including dip-pen nanolithography (DPN, a scanning probe lithography technique where an atomic force microscope tip is used to create patterns directly...

Published: 4/1/2025 | Inventor(s): Nathaniel Cady, Magnus Bergkvist, Alison Gracias

Keywords(s): Technologies

Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Engineering, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology

Intervertebral Disc Repair Using a 3D Porous Hybrid Protein Nanoscaffold

Histological analysis of rat intervertebral disc tissue prior to (left) and post injury (center) compared to 6 weeks post treatment (right). Invention Summary: Degeneration of fibrocartilaginous tissues, such as intervertebral discs (IVD), knee menisci, and other tendon-bone junctions, can lead to debilitating pain. IVD degeneration is the...

Published: 3/25/2025 | Inventor(s): Ki-Bum Lee, Letao Yang, Inbo Han

Keywords(s):

Category(s): Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Biomaterials

NanoScript & MitoScript – Nanoparticles for Modulation of Endogenous DNA at the Transcription Level

NanoScript (left) for the regulation of DNA transcription and MitoScript (right) for the regulation of mDNA transcription. Invention Summary: As of 2022, 1 in 4000 people are affected by mitochondrial disorders. Currently there are no cures for many mitochondrial disorders and treatment plans typically only address alleviating...

Published: 11/25/2024 | Inventor(s): Ki-Bum Lee, Sy-Tsong Chueng, Hyeon-Yeol Cho, Young Sup Yoon

Keywords(s): Nanoparticles

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology

miRNA Nanoparticles for Targeted Enhancement of Thermogenic Adipocyte Generation

Introduction of a promising anti-obesity novel MiR-133a, Zipper nanoparticle treatment results in enhanced Prdm16 and Ucp1 expression, resulting in adipocyte browning. Invention Summary: Over 40% of adults are overweight and over 15% of adults are living with obesity. Obesity is a major contributor to various causes of mortality including...

Published: 1/8/2025 | Inventor(s): Sarah Nevins, Ki-Bum Lee, Thanapat Pongkulapa, Sang Ah Yi

Keywords(s): Cardiovascular, Diabetes & Metabolic Disorders, Nanoparticles, Nanotechnology

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology

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