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NanoScript & MitoScript – Nanoparticles for Modulation of Endogenous DNA at the Transcription Level
​ NanoScript (left) for the regulation of DNA transcription and MitoScript (right) for the regulation of mDNA transcription. Invention Summary: As of 2022, 1 in 4000 people are affected by mitochondrial disorders. Currently there are no cures for many mitochondrial disorders and treatment plans typically only address alleviating...
Published: 11/25/2024   |   Inventor(s): Ki-Bum Lee, Sy-Tsong Chueng, Hyeon-Yeol Cho, Young Sup Yoon
Keywords(s): Nanoparticles
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
miRNA Nanoparticles for Targeted Enhancement of Thermogenic Adipocyte Generation
​ Introduction of a promising anti-obesity novel MiR-133a, Zipper nanoparticle treatment results in enhanced Prdm16 and Ucp1 expression, resulting in adipocyte browning. Invention Summary: Over 40% of adults are overweight and over 15% of adults are living with obesity. Obesity is a major contributor to various causes of mortality including...
Published: 11/12/2024   |   Inventor(s): Sarah Nevins, Ki-Bum Lee, Thanapat Pongkulapa, Sang Ah Yi
Keywords(s): Cardiovascular, Diabetes & Metabolic Disorders, Nanoparticles, Nanotechnology
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
A Three-Buckyball Platform to Synthesize Structurally Defined Water-Soluble Metallofullerene Derivatives
​ Invention Summary: Fullerenes, an allotrope of carbon, are polyhedral closed cages. Fullerenes are able to host additional atoms within their inner spheres. Fullerenes hosting electropositive metals (e.g. Sc, Gd, La), known as endohedral metallofullerenes (EMFs), are especially interesting as the encapsulated metals provide additional...
Published: 11/26/2024   |   Inventor(s): Jianyuan Zhang, William Kopcha, Yue Sun, Rohin Biswas, Yanbang Li
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Medical Imaging, Technology Classifications > Nanotechnology
Enhancing CAR Macrophage Efferocytosis via Surface Engineered Lipid Nanoparticles Targeting LXR Signaling
CAR-Macrophage efficiently uptakes apoptotic cell and cholesterol crystals via β-cyclodextrin, activating the LXR pathway and promoting cholesterol efflux Invention Summary: Atherosclerosis is considered the major cause of cardiovascular disease, leading to ischemic heart disease and ischemic strokes, the 1st and 5th largest causes of...
Published: 1/7/2025   |   Inventor(s): Ki-Bum Lee, Skylar Chuang
Keywords(s):  
Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Nanotechnology
Flame Synthesis of Carbon-Based Films on Liquid Surfaces
​ Schematic of an ethylene-air premix flame impinging on the liquid surface of a distilled water bath, producing carbon-based films on the liquid surface Invention Summary: The production of thin, carbon-based films on liquid surfaces often leaves behind MgO impurities, requires additional purification steps, and is reliant on the use of substrates,...
Published: 10/21/2024   |   Inventor(s): Stephen Tse, Chuiyuan Meng, Bernard Kear
Keywords(s):  
Category(s): Technology Classifications > Electronics/Semiconductor, Technology Classifications > Nanotechnology, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Sensors
Improved Chemical-Mechanical Polishing Slurry Composition and Method to Improve Polishing of Metals and Non-metals Using Cerium Oxide Nanoparticles
Reducing manufacturing time, cost, and labor by employing chemistry to transform a two-step process into an easily controlled single-step. Background: Integrated circuits are built of many layers. Each layer must be perfectly flat so that connections line up between layers and electricity flows properly throughout. Conventional CMP systems consist...
Published: 9/20/2024   |   Inventor(s): Christopher Netzband, Kathleen Dunn
Keywords(s): abrasive, cerium, cerium oxide, chemical activity, chemical mechanical polishing, CMP, CMP slurries, dielectrics, fiber optics, integrated circuit, lens, mechanical polish, metallic surface, optics, polish, polishing, semiconductor wafers, semiconductors, slurry, surface finishing, surface quality
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
Lux Semiconductors
­https://www.luxsemiconductors.com/ https://www.luxsemiconductors.com/ https://suny.technologypublisher.com/files/sites/lux_logo-206-cropped-1-400x400.jpg https://suny.technologypublisher.com/files/sites/lux_logo-206-cropped-1-400x400.jpg
Published: 6/7/2024   |   Inventor(s):  
Keywords(s): Startups
Category(s): Campus > SUNY Polytechnic Institute, Technology Classifications > Electronics, Technology Classifications > Nanotechnology
NanoHydroChem
https://nanohydrochem.com/ https://nanohydrochem.com/ https://suny.technologypublisher.com/files/sites/nanohydrochem.png https://suny.technologypublisher.com/files/sites/nanohydrochem.png
Published: 2/29/2024   |   Inventor(s):  
Keywords(s): Startups
Category(s): Campus > University at Buffalo, Technology Classifications > Energy, Technology Classifications > Nanotechnology, Technology Classifications > Materials and Chemicals
Graphene Ink and 3D Printing for Aerogel Water Purification Filters
A graphene-based ink suitable for Direct Ink Write (DIW) 3D printing of uniquely structured water purification filters. Background: Graphene aerogels are incredibly light weight 3-D versions of 2-D graphene. In many respects they make an ideal filter for purifying water with their high surface area, re-usability, and binding ability. Typically...
Published: 2/27/2024   |   Inventor(s): Nirupam Aich, Arvid Masud, Chi Zhou
Keywords(s): Technologies
Category(s): Technology Classifications > Environment, Technology Classifications > Nanotechnology, Campus > University at Buffalo
Multi-Faceted Anti-inflammatory Neuroprotective Nanoparticles for Treating Alzheimer’s Disease
​ Invention Summary: Alzheimer's disease (AD) is characterized by progressive neurodegeneration and a high mortality rate in the elderly. Current therapeutic strategies fall short in halting the underlying cognitive decline and nerve cell damage. The primary features of AD are the accumulation of extracellular amyloid plaques, uncontrolled...
Published: 10/21/2024   |   Inventor(s): Hoda Gebril, Prabhas Moghe, Kathryn Uhrich
Keywords(s):  
Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology
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