Search Results - technology+classifications+%3e+medical+%3e+neuroscience

47 Results Sort By:
Multimodal Asymmetric Rhythmic Cueing for Gait Rehabilitation in Stroke Survivors
Advantages: Sensory cues improve step length and timing, enhancing walking coordination Combined auditory-tactile cues adapt to individual needs for more effective therapy Braking force and stability improvements reduce fall risks These methods activate neuroplasticity, promoting lasting motor improvements Summary: Post-stroke rehabilitation...
Published: 12/20/2024   |   Inventor(s): Seok Kim, Kyle Reed
Keywords(s): Devices for Disabilities / Rehabilitation
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Biomedical Engineering
Multimodal Asymmetric Rhythmic Cueing for Gait Rehabilitation in Stroke Survivors
Advantages: Sensory cues improve step length and timing, enhancing walking coordination Combined auditory-tactile cues adapt to individual needs for more effective therapy Braking force and stability improvements reduce fall risks These methods activate neuroplasticity, promoting lasting motor improvements Summary: Post-stroke rehabilitation...
Published: 12/17/2024   |   Inventor(s): Kyle Reed, Seok Kim
Keywords(s): Devices for Disabilities / Rehabilitation
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Biomedical Engineering
Modulating Molecular Chaperone DnaJB6b as a Novel Method to Regulate Tau Seeding and Propagation
­Advantages: Semi-high throughput screening accelerates drug discovery by quickly identifying candidates, reducing time to market, and gaining a competitive edge. Molecular Chaperone reduces tau aggregation, preserving cognitive function and improving patient quality. Employs a precision medicine approach targeting tauopathy mechanisms, potentially...
Published: 9/11/2024   |   Inventor(s): Abigail Esquivel, Laura Blair
Keywords(s): Alzheimer's Disease, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Therapeutics
Drug-Induced Activation of the Reelin Signaling System
­Advantages: Small, soluble drug with therapeutic potential Independent Reelin signaling pathway activation More able to pass through the BBB than Reelin Summary: The Reelin signaling pathway is an essential component of the developing and adult central nervous systems. The signaling cascade assists with the regulation of developing neurons...
Published: 7/24/2024   |   Inventor(s): Edwin Weeber, Melinda Peters, Qingyou Li, Hana Soueidan
Keywords(s):  
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Neuroscience
The Sudden Head Acceleration & Kinetic Encephalopathy (SHAKEn™) Device for Preclinical Modeling of Rotational Brain Injury
­Advantages: User control to adjust the positioning of the body plate (in the x/y plane) to optimize spinal alignment relative to the axis of rotation prior to insult. An aeronautics-grade angular rate sensor for direct measurement of angular velocity and to calculate rotational acceleration of the head. An electric plug to power accelerations...
Published: 7/18/2024   |   Inventor(s): Travis Jackson
Keywords(s): Animal Models, Lab Apparatus, Laboratory Devices, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience
Novel Helical Peptodomimetics that Prevent the Formation of Aβ Oligomerization in Alzheimer’s Disease (AD)
­Advantages: Developed sulfonyl-γ-AA peptide helical peptidomimetics that can prevent the formation of neurotoxic Aβ oligomerization. High Specificity: The lead sulfonyl-γ-AApeptide helical foldamer, Ab-6, exhibits precise targeting to the central region of Aβ42 and induces α-helix conformation in Aβ. Sequence-Specific...
Published: 11/6/2024   |   Inventor(s): Jianfeng Cai, Heng Liu
Keywords(s): Alzheimer's Disease, Biotechnology, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Neuroscience
New Device Material for a Flexible Chronic Implantable Neural Interface
­Advantages: Superior biocompatibility reduces immune responses. Excellent electrical conductivity enhances signal transmission. Exceptional mechanical strength enables durable and flexible probes. Summary: Implantable neural interfaces (INIs) are devices configured to connect with the human nervous system through electrical means. Such...
Published: 9/3/2024   |   Inventor(s): Stephen Saddow, Chenyin Feng, Christopher Frewin
Keywords(s): Drug Delivery and Nanomedicine, Medical Therapeutics Cell Therapy, Nanotechnology, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biomaterials, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience
Secreted UBE3A for the Treatment of Neurological Disorders
­Advantages: Novel vector, composition, and method of treating a neurological disorder with UBE3A deficiency. High fidelity to human Angelman syndrome. Facilitates comprehensive symptom representation for diverse treatment investigations. Allows innovative experiments for pioneering treatment development. Summary: Angelman...
Published: 1/2/2024   |   Inventor(s): Kevin Nash
Keywords(s): Animal Models, Medical Therapeutics Gene Therapy, Neurodegenerative Diseases, Neuroscience
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Neuroscience
Conditional FKBP51 Over-expression Transgenic Mouse
­Advantages: Created a transgenic mice model that allows researchers to precisely control the expression of human FKBP51. Offers a tailored approach to studying psychiatric disorders, enabling the development of personalized treatments. Enhances the understanding of the molecular mechanisms underlying psychiatric disorders such as depression,...
Published: 11/13/2024   |   Inventor(s): Chad Dickey(VA) (DECEASED - See Notes), Laura Blair, Bo Zhang
Keywords(s): Animal Models, Psychiatry / Mental Health
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Therapeutics
Investigating the Role of BIN1's SH3 Domain in Alzheimer's Desease
­Advantages: The approach of targeting BIN1, a gene associated with AD increases the likelihood of finding effective therapeutic interventions. Determining the crystal structure of BIN1's SH3 domain provides detailed structural information which is crucial for designing small molecule inhibitors. The research reports promising preliminary...
Published: 1/23/2024   |   Inventor(s): Gopal Thinakaran
Keywords(s): Medical Therapeutics Gene Therapy, Neurodegenerative Diseases, Neuroscience, Small Molecules
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Medical Diagnostics
1 2 3 4 5