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Search Results - zzdiabetes
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A novel mouse model (TRE-HuAmy line) to achieve spatial and temporal control of human amylin transgene expression
Advantages Enables the in vivo switching on or off human amylin expression through the administration/ withdrawal of DOX Spatially restricted transgene activation: crossing tissue-specific rtTA/tTA lines achieves localized amylin expression without off-target effects. Single-copy Rosa26 knock-in for consistent expression: integration at Rosa26...
Published: 6/3/2025
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Inventor(s):
Gopal Thinakaran
,
Florin Despa
Keywords(s):
Category(s):
Technology Classifications > Research Tools/Copyright > Animal Models
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Technology Classifications > Medical > Neuroscience
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zzDiabetes