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Search Results - zzneurodegenerative+diseases+treatment
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TREM2 Binds to Specifically Structured Heparan Sulfate
Advantages: Discovered novel structural interactions between HS and TREM2, associated with neurodegeneration High-affinity binding: TREM2 specifically interacts with Heparan Sulfate (HS) modified with 6-O-sulfation and iduronic acid, enabling precise microglial modulation compared to broad-spectrum anti-inflammatory strategies. Defined structural...
Published: 5/15/2025
|
Inventor(s):
Lianchun Wang
,
Ilayda McMillan
Keywords(s):
Immunology
,
Neurodegenerative Diseases
,
Neuroscience
Category(s):
zzNeurodegenerative Diseases Treatment
,
Technology Classifications > Medical > Neuroscience
,
Technology Classifications > Medical > Therapeutics