Search Results - zzneurodegenerative+diseases+treatment

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Binding Between TREM2 and Heparan Sulfate Delineates the Role of Microglia in AD and Reveals Novel Treatment Strategies
Advantages: Discovered novel structural interactions between HS and TREM2, associated with neurodegeneration High-affinity binding: TREM2 specifically interacts with Heparan Sulfate (HS) modified with 6-O-sulfation and iduronic acid, enabling precise microglial modulation compared to broad-spectrum anti-inflammatory strategies Defined structural...
Published: 10/14/2025   |   Inventor(s): Lianchun Wang, Ilayda McMillan
Keywords(s): Immunology, Neurodegenerative Diseases, Neuroscience
Category(s): zzNeurodegenerative Diseases Treatment, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Therapeutics
Redirecting Neurogenesis Using Drug-Loaded Exosomes Derived from Mesenchymal Stem Cells Educated in Pro-Inflammatory Environment
Advantages Targeted modulation of neuroinflammation using Mesenchymal Stem Cell (MSC)-derived “induced” exosomes Intranasal exosome delivery facilitates improved Blood-Brain Barrier (BBB) penetration Addresses underlying neuroinflammatory processes driving neurodegenerative diseases, moving beyond symptomatic treatment approaches Summary Neurodegenerative...
Published: 1/22/2026   |   Inventor(s): Eleni Markoutsa
Keywords(s): Biotechnology, Health Tech, Neuroscience, Peptides
Category(s): Technology Classifications > Medical, zzNeurodegenerative Diseases Treatment, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Therapeutics