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Leg Isoinertial Measurement Brace (LIMB)
Advantages: Portable & Lightweight – Ideal for clinics with limited space Accurate & Replicable – Eliminates human error for reliable results Motorized Torque Input – Ensures consistent, precise measurements Real-Time Monitoring – Arduino-based control system for tracking rehabilitation Ergonomic & Comfortable...
Published: 2/25/2025   |   Inventor(s): Aidan Foy, Jacob Loufek, David Botero, Nathan Schilaty, Benjamin Keister, Stephanie Carey
Keywords(s): Mechanical Engineering
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Medical Sensors, Technology Classifications > Medical > Biomedical Engineering
Multiphasic Localized in vivo Molecular Delivery
Advantages: Asymmetric biphasic pulses significantly reduced stimulation of skeletal muscle contractions in vivo and enhanced gene delivery Enables delivery of insulin and glucokinase to replace daily injections with long-term, non-immunogenic protein expression in skeletal muscle Higher-efficiency gene therapies avoid immunogenicity and off-target...
Published: 2/21/2025   |   Inventor(s): Anna Bulysheva, Mark Jaroszeski, Richard Heller
Keywords(s): Cancer Treatment, Drug Delivery Systems, Medical Therapeutics Gene Therapy, Wound and Tissue Healing
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Cancer, Technology Classifications > Medical > Biomedical Engineering
SLURP1 is a Novel Therapeutic Target for Ocular Surface Inflammatory Disorders
Advantages: Identification and validation of SLURP1 as a therapeutic target for treating ocular therapies SLURP1 enhances antioxidant defenses SLURP1 counteracts TGF-β-induced EMT in corneal epithelial cells Potential for Formulating eye care products with SLURP1 to mitigate oxidative stress and maintain corneal epithelial homeostasis (e.g....
Published: 1/24/2025   |   Inventor(s): Shivalingappa Swamynathan, Sudha Swamynathan, Satinder Kaur
Keywords(s): Ophthalmology, Pharmaceuticals
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Ophthalmology
Gait Rehabilitation: Harnessing Multimodal Rhythmic Asymmetric Sensory Cues
Advantages: Sensory cues improve step length and timing, enhancing walking coordination Combined auditory-tactile cues adapt to individual needs for more effective therapy Braking force and stability improvements reduce fall risks These methods activate neuroplasticity, promoting lasting motor improvements Summary: Tech ID 20B150 and...
Published: 1/31/2025   |   Inventor(s): Seok Kim, Kyle Reed
Keywords(s): Devices for Disabilities / Rehabilitation
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Biomedical Engineering
Gait Rehabilitation: Harnessing Multimodal Rhythmic Asymmetric Sensory Cues
Advantages: Sensory cues improve step length and timing, enhancing walking coordination Combined auditory-tactile cues adapt to individual needs for more effective therapy Braking force and stability improvements reduce fall risks These methods activate neuroplasticity, promoting lasting motor improvements Summary: Tech IDs 20B150 and...
Published: 1/31/2025   |   Inventor(s): Kyle Reed, Seok Kim
Keywords(s): Devices for Disabilities / Rehabilitation
Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Biomedical Engineering
Sensitive and Selective Synthetic Glucose Receptor Designed for Monitoring in Biomedical and Diagnostic Applications
Advantages: Highly sensitive glucose sensor with strong potential for use in biomedical diagnostics and continuous glucose monitoring. Flexible, adaptive binding pocket that selectively targets glucose’s functional groups, improving specificity and detection accuracy. Reversible, non-covalent binding to glucose, allowing real-time response...
Published: 1/17/2025   |   Inventor(s): Wenqi Liu
Keywords(s): Biotechnology, Diabetes, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical
Treating Age-Related Hearing Loss with Rapamycin and Its Derivatives
Advantages: Novel Application of FDA approved drugs, rapamycin and its derivatives, for treating age-related hearing loss (ARHL). Targeting mTOR alleviates oxidative stress and inflammation in the cochlea, enhancing cellular health and resilience to age-related damage. Potential to Reverse or Delay Age-related hearing loss (ARHL) in patients. Summary: Age-related...
Published: 1/17/2025   |   Inventor(s): Robert Frisina, Xiaohua Zhu, Bo Ding, Xiaoxia Zhu
Keywords(s): Pharmaceuticals, Therapeutics
Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices
Human Adipose-Derived Stem Cell Exosomes’ Packaging for Use at Room Temperature
­Advantages: Promotes wound healing and supports positive long-term outcomes Reduces oxidative stress in human dermal fibroblasts (HDF) by exposing them to a composition containing adipose stem cell-derived exosomes Promising solution specifically tailored for penetrating wounds such as during military combat Summary: Penetrating injuries...
Published: 9/17/2024   |   Inventor(s): Niketa Patel
Keywords(s): Wound and Tissue Healing
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Therapeutics
Kcnab2 Conditional Knockout Mouse Model
­Advantages: A new Kcnab2 exon 4-floxed mice, suitable for experimental models to study muscle development, regeneration, and pathogenesis Kcnab2 exon 4-floxed mice were successfully generated using CRISPR/Case9 technology Allows for specific study of the Kcanb2 function on skeletal muscle (e.g. TA) without significant changes in the brain...
Published: 1/24/2025   |   Inventor(s): Srinivas Tipparaju
Keywords(s): Animal Models, Cardiological Diseases Treatment, Cardiovascular Diseases
Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Cell & Tissue Engineering
The Sudden Head Acceleration & Kinetic Encephalopathy (SHAKEn™) Device for Preclinical Modeling of Rotational Brain Injury
­Advantages: User control to adjust the positioning of the body plate (in the x/y plane) to optimize spinal alignment relative to the axis of rotation prior to insult. An aeronautics-grade angular rate sensor for direct measurement of angular velocity and to calculate rotational acceleration of the head. An electric plug to power accelerations...
Published: 7/18/2024   |   Inventor(s): Travis Jackson
Keywords(s): Animal Models, Lab Apparatus, Laboratory Devices, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience
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