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Human Adipose-Derived Stem Cell Exosomes’ Packaging for Use at Room Temperature

Advantages: Promotes wound healing and supports positive long-term outcomes Reduces oxidative stress in human dermal fibroblasts (HDF) by exposing them to a composition containing adipose stem cell-derived exosomes Promising solution specifically tailored for penetrating wounds such as during military combat Summary: Penetrating injuries...

Published: 9/17/2024 | Inventor(s): Niketa Patel

Keywords(s): Wound and Tissue Healing

Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Therapeutics

Kcnab2 Conditional Knockout Mouse Model

Advantages: A new Kcnab2 exon 4-floxed mice, suitable for experimental models to study muscle development, regeneration, and pathogenesis. Kcnab2 exon 4-floxed mice were successfully generated using CRISPR/Case9 technology. Allows for specific study of the Kcanb2 function on skeletal muscle (e.g. TA) without significant changes in the brain...

Published: 9/20/2024 | Inventor(s): Srinivas Tipparaju

Keywords(s): Animal Models, Cardiological Diseases Treatment, Cardiovascular Diseases

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Cell & Tissue Engineering

The Sudden Head Acceleration & Kinetic Encephalopathy (SHAKEn™) Device for Preclinical Modeling of Rotational Brain Injury

Advantages: User control to adjust the positioning of the body plate (in the x/y plane) to optimize spinal alignment relative to the axis of rotation prior to insult. An aeronautics-grade angular rate sensor for direct measurement of angular velocity and to calculate rotational acceleration of the head. An electric plug to power accelerations...

Published: 7/18/2024 | Inventor(s): Travis Jackson

Keywords(s): Animal Models, Lab Apparatus, Laboratory Devices, Neuroscience, Research Tools

Category(s): Technology Classifications > Research Tools/Copyright > Animal Models, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience

Compact System and Method for Treating Urine and Other Wastewater

Advantages: The system offers enhanced sustainability by efficiently treating waste with minimal consumable inputs and hazardous byproducts. SAMBR provides a compact solution, achieving high treatment efficiency within the constrained space of spacecraft. The technology supports long-duration missions by recovering valuable resources, ensuring...

Published: 7/10/2024 | Inventor(s): Daniel Yeh, Talon Bullard, Luke Roberson, Daniella Saetta, Alexandra Smith

Keywords(s):

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Energy & Environment > Energy Engineering, Technology Classifications > Engineering > Chemical Engineering

Novel Helical Peptodomimetics that Prevent the Formation of Aβ Oligomerization in Alzheimer’s Disease (AD)

Advantages: Developed sulfonyl-γ-AA peptide helical peptidomimetics that can prevent the formation of neurotoxic Aβ oligomerization. High Specificity: The lead sulfonyl-γ-AApeptide helical foldamer, Ab-6, exhibits precise targeting to the central region of Aβ42 and induces α-helix conformation in Aβ. Sequence-Specific...

Published: 9/12/2024 | Inventor(s): Jianfeng Cai, Heng Liu

Keywords(s): Alzheimer's Disease, Biotechnology, Neurodegenerative Diseases

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Neuroscience

Smart Mosquito Trap For Mosquito Classification

Advantages: Automates mosquito identification, reducing manual inspection efforts. Provides immediate species data, aiding timely mosquito control decisions. Integrates AI for proactive surveillance and targeted management strategies. Summary: Current methods of identifying mosquitoes trapped for research or control purposes are labor-intensive...

Published: 9/20/2024 | Inventor(s): Sriram Chellappan, Stephen Saddow, Brandon Wolfram

Keywords(s): Artificial Intelligence, Environmental Sciences

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Medical Devices, Technology Classifications > Data/AI > D/AI Imaging

Flexible Nanomaterial Sensors

Advantages: High sensitivity and versatility for monitoring various parameters, suitable for applications like medical tapes, wearable electronics, and artificial eardrums. Reduced material waste and lower production costs through non-contact printing, eliminating mask cleaning. Scalable and efficient manufacturing with electric field-assisted...

Published: 6/26/2024 | Inventor(s): Ying Zhong, Long Wang, Rui Kou

Keywords(s): Electronics, Sensors

Category(s): Technology Classifications > Computer Science > C/S Sensors, Technology Classifications > Electronics > Electronics Sensors, Technology Classifications > Advance Materials > A/M Manufacturing, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Medical Sensors

New Device Material for a Flexible Chronic Implantable Neural Interface

Advantages: Superior biocompatibility reduces immune responses. Excellent electrical conductivity enhances signal transmission. Exceptional mechanical strength enables durable and flexible probes. Summary: Implantable neural interfaces (INIs) are devices configured to connect with the human nervous system through electrical means. Such...

Published: 9/3/2024 | Inventor(s): Stephen Saddow, Chenyin Feng, Christopher Frewin

Keywords(s): Drug Delivery and Nanomedicine, Medical Therapeutics Cell Therapy, Nanotechnology, Neurodegenerative Diseases

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biomaterials, Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Neuroscience

Novel Device for Applying Electrically Based Therapeutics

Advantages: Novel device to perform electrically based therapies for: soft tissue ablation (irreversible electroporation; IRE), Drug Delivery (electrochemotherapy; ECT), Gene delivery (gene electro transfer; GET). Modular array technology integrates temperature modulation to reduce voltage requirements, impedance monitoring to control applied...

Published: 8/27/2024 | Inventor(s): Richard Heller, Mark Jaroszeski

Keywords(s):

Category(s): Technology Classifications > Medical > Medical Devices, Technology Classifications > Medical > Biomedical Engineering

Localized In Vivo Electro Gene Therapy for Type 1 Diabetes

Advantages: Novel gene therapy for Type 1 Diabetes (T1D) focused on reprogramming skeletal muscle cells to modulate glucose levels in vivo. Nano plasmid DNA of insulin and glucokinase decreased glucose levels in vitro and in vivo and enhanced insulin expression and secretion. Groundbreaking treatment for long-lasting blood glucose control...

Published: 7/2/2024 | Inventor(s): Anna Bulysheva

Keywords(s): Diabetes, Medical Therapeutics Gene Therapy

Category(s): Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Medical > Biotechnology

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