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Antiviral Properties of Deep-Sea Coral Metabolites
Advantages: A novel compound for developing new antiviral drugs extracted from the Irish deep-sea soft coral Anthoteibinene B exhibits significant antiviral activity against Respiratory Syncytial Virus (RSV) without cytotoxic effects N,N-dimethylaminoethyl substituents further enhance antiviral properties by improving solubility, bioavailability,...
Published: 11/7/2024   |   Inventor(s): Bill Baker, Stine Olsen, Sam Afoullouss, Kim Teng, Michael Teng, Louise Allcock, Mark Johnson
Keywords(s): Antiviral Therapeutics
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Chemistry, Technology Classifications > Medical > Therapeutics
­NOVEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
­NOVEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024   |   Inventor(s): Evan Obrien, Kaavya Kumar, Brian Kobilka, Susruta Majumdar, Vipin Rangari
Keywords(s): Opiod, Pain
Category(s): Technology Classifications > Chemistry
Photodegradation Protection of Polymeric Materials by Encapsulating with Inorganic Composites and Applications Thereof
­Advantages: Boosts the average lifespan of polymers preventing them from undergoing UV-induced photodegradation. Decreases the frequency of replacements and repair process, which translates into tremendous cost savings. Summary: Various fields employ polymeric and organic materials which are prone to photodegradation under UV radiation...
Published: 7/9/2024   |   Inventor(s): Elias Stefanakos, Sesha Srinivasan
Keywords(s):  
Category(s): Technology Classifications > Electronics > Electronics Laser, Technology Classifications > Advance Materials, Technology Classifications > Chemistry, Technology Classifications > Electronics > Nanotechnology, Technology Classifications > Engineering > Electrical Engineering
Intermetallic Fe Based Catalysts for Light Olefin Production
­Advantages: High Selectivity: Up to 45% light olefin selectivity with CO2 included. Exceptional Stability: Maintains performance over a 72-hour run. Customizable Reactivity: Fe:In ratios tune surface composition for optimized olefin production and reduced by-products. Summary: This technology addresses a critical need in the chemical industry...
Published: 8/22/2024   |   Inventor(s): John Kuhn, Babu Joseph, Yang He
Keywords(s): Chemistry and Chemical Engineering, Material Science
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Chemistry, Technology Classifications > Energy & Environment > Energy Engineering
Dye and Polyphenol Modified Carbon Quantum Dots (CQ-dots) with Tunable Fluorescent, Antipathogenic, Antioxidant and Anticancer Properties
­Advantages: Enhanced optical properties enable superior bioimaging and precise detection in medical diagnostics and research. Multifunctional antipathogenic properties make the modified CQ-dots effective against a wide range of microorganisms, addressing healthcare demands for antimicrobial materials. Versatile applications across industries,...
Published: 6/27/2024   |   Inventor(s): NURETTIN SAHINER, Ramesh Ayyala
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Electronics > Nanotechnology, Technology Classifications > Chemistry, Technology Classifications > Medical > Biomaterials
Novel Compounds and Methods for Treating Metastatic Melanoma and Prostate Cancer
­Advantages: Precision Targeting: Selective cancer cell targeting minimizes harm to healthy tissues, enhancing safety. Preclinical Efficacy: Induces cancer cell apoptosis, showing promise for treating metastatic melanoma and prostate cancer. Scientific Rigor: Grounded in robust research, offering innovative oncology solutions. Summary: Metastatic...
Published: 7/11/2024   |   Inventor(s): Wishrawana Ratnayake, Kirpal Bisht, Mildred Acevedo-Duncan
Keywords(s): Cancer Treatment Melanoma, Cancer Treatment Prostate Cancer
Category(s): Technology Classifications > Chemistry, Technology Classifications > Medical > Biomedical Engineering, Technology Classifications > Cancer > Cancer Treatment Melanoma, Technology Classifications > Cancer
­ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR AND CANNABINOID RECEPTOR 1
­ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR AND CANNABINOID RECEPTOR 1 Researchers at Stanford have synthesized a potential novel class of pain relief drugs. Traditional opioids, while highly effective for acute pain management, have historically been prescribed as long-term analgesic treatments despite their well-known addictive properties....
Published: 9/14/2023   |   Inventor(s): Evan Obrien, Brian Kobilka, Krishna Kumar
Keywords(s): Analgesic, Opiod, Pain
Category(s): Technology Classifications > Chemistry
­COMPOSITIONS AND METHODS FOR INHIBITING FSP1
­COMPOSITIONS AND METHODS FOR INHIBITING FSP1 Researchers at UC Berkeley have developed ferroptosis suppressor protein 1 (FSP1) inhibitors and methods for their use in cancer therapy. Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death that is characterized by the accumulation of oxidatively damaged phospholipids. Ferroptosis...
Published: 10/2/2024   |   Inventor(s): James Olzmann, Kirill Bersuker, Julia Schaletzky, Edward Wehri, Joseph Hendricks, Cody Doubravsky
Keywords(s): Cancer, Ferroptosis, FSP1
Category(s): Technology Classifications > Chemistry
Corona Discharge Directed 3D Structure Construction
­Advantages: CE-3DP enables rapid 3D structure growth within seconds, accelerating production and design iterations. The technology minimizes material waste, maximizing material utilization and cost efficiency. With precise control over structure shape and accommodating various materials, CE-3DP offers versatile applications in diverse industries. Summary:...
Published: 7/31/2023   |   Inventor(s): Ying Zhong, Zijian Weng
Keywords(s): Nanotechnology
Category(s): Technology Classifications > Chemistry, Technology Classifications > Advance Materials > A/M Manufacturing, Technology Classifications > Engineering > Additive Manufacturing
METHODS AND COMPOSITIONS RELATED TO LANTHANIDE-ENCODED MICROBEADS
METHODS AND COMPOSITIONS RELATED TO LANTHANIDE-ENCODED MICROBEADS Researchers at Stanford University have developed a bespoke method for multiplexing beads in bioassays that expands the possible coding space when compared to available bead barcoding technologies. Multiplexed bioassays have drastically improved our understanding of complex biological...
Published: 3/17/2023   |   Inventor(s): Yinnian Feng, Adam White, Jamin Hein, Polly Fordyce
Keywords(s): Barcoded Beads, Bioassay, Bioconjugation, Lanthanide, Microbeads, Multiplexed
Category(s): Technology Classifications > Chemistry
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