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Process for Oxidative Coupling of Nitroalkanes and Organoborons
Advantages Eliminates hazardous, pyrophoric organometallic reagents and toxic, explosive azides for safer manufacturing Runs safely in water under mild conditions, simplifying manufacturing workflows Uses stable, affordable reagents to cut costs and enable broad substrate versatility Speeds up production of key amine building blocks for drug discovery Summary α-Tertiary...
Published: 7/21/2026   |   Updated: 7/21/2026   |   Inventor(s): Minsoo Ju, Nayoung Kim
Keywords(s): Agriculture, Chemistry and Chemical Engineering, Pharmaceuticals
Category(s): Technology Classifications > Chemistry, Technology Classifications > Medical > Pharmaceuticals
A novel means to generate high pressure
Title: A novel means to generate high pressure Tech ID: 2024-009 Status: Active Category: High-Pressure Physics, Materials Science, and Spectroscopy Executive Statement: A new method to generate ultra-high pressures while improving sample accessibility through laser-drilled diamond culets and plastic flow in metallic gaskets. Description: This...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Michael Pravica
Keywords(s):  
Category(s): Technology Classifications > Engineering & Manufacturing, Technology Classifications > Chemistry
Green Synthesis of Unsymmetrical Phosphorous Disulfides
Title: Green Synthesis of Unsymmetrical Phosphorous Disulfides Tech ID: 2024-005 Status: Active Category: Green Chemistry and Synthetic Organic Chemistry Executive Statement: A sustainable, mild, and additive-free method for synthesizing unsymmetrical phosphorous disulfides using renewable solvents. Description: This technology introduces...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Jun Yong Kang, Jeffrey Ash
Keywords(s): Chemistry
Category(s): Technology Classifications > Chemistry, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
New Synthetic Routes toward CBB3001 and Their Derivatives
Title: New Synthetic Routes toward CBB3001 and Their Derivatives Tech ID: 2024-004 Status: Active Category: Chemistry, Biochemistry, Pharmaceutical Development Executive Statement: Efficient synthetic methods for producing anti-cancer agents based on CBB3001 and its derivatives. Description: This technology introduces novel and optimized...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Jun Yong Kang, Jeffrey Ash, Citlally Lopez
Keywords(s):  
Category(s): Technology Classifications > Chemistry, Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery
Modulation and Utility of DCAF10-associated CRL4 Ubiquitin Ligase Complexes Targeting Proteins for Proteolysis
This technology utilizes the CRL4-DCAF10 ubiquitin ligase complex to target and tag specific proteins for proteasomal degradation. By using chemical inhibitors and engineered PROTAC molecules, the system recruits target proteins to catalyze their destruction and control cellular protein levels. This mechanism provides a powerful platform for drug discovery...
Published: 7/17/2026   |   Updated: 7/17/2026   |   Inventor(s): Hui Zhang
Keywords(s):  
Category(s): Technology Classifications > Therapeutics, Pharmaceuticals, Drug Delivery, Technology Classifications > Chemistry
GROUP ACTINIDE SEPARATION PROCESS (GRASP) FOR SUSTAINABLE NUCLEAR FUEL CYCLE
GRASP is an innovative process designed to enhance the separation of actinides to promote a more sustainable nuclear fuel cycle. The Invention The Group Actinide Separation Process (GRASP) advances nuclear fuel cycle sustainability by improving the efficiency and selectivity of actinide separation. Developed at the bench prototype stage, this technology...
Published: 7/27/2026   |   Updated: 7/17/2026   |   Inventor(s): Artem Gelis, Logan Smith, Quinn Summerfield
Keywords(s): Chemistry, Energy & Environment - Energy
Category(s): Technology Classifications > Energy & Environment, Technology Classifications, Technology Classifications > Chemistry
Phosphonium Metal Halide Semiconductors for PFAS Detection
Advantages Exceptional water stability, with demonstrated structural integrity for over 22 months in aqueous environments Improved thermal stability by up to 160 °C higher than conventional ammonium-based analogues Tunable optical and electrochemical properties suitable for sensing, optoelectronics, and energy applications Enables low-cost,...
Published: 6/22/2026   |   Updated: 2/27/2026   |   Inventor(s): Ioannis Spanopoulos, Ali Azmy, Zois Syrgiannis, Anand Tiwari
Keywords(s): Chemistry and Chemical Engineering, Environmental Sciences, Nanotechnology
Category(s): Technology Classifications > Advance Materials, Technology Classifications > Chemistry, Technology Classifications > Electronics > Nanotechnology, Technology Classifications > Energy & Environment, Technology Classifications > Electronics > Electronics Sensors
ICA‑1S and ζ‑Stat: Selective aPKC Inhibitors for Anti‑Angiogenic Control Neuroblastoma
Advantages Upstream pathway control: Suppresses VEGF‑A by targeting aPKC, a master regulator of angiogenic signaling. Selective, small-molecule mechanism: offers lower immunogenicity and easier development than antibody-based therapies. Combination-therapy ready: upstream angiogenic pathway control enables synergy with existing treatments. Summary Neuroblastoma...
Published: 7/9/2026   |   Updated: 2/16/2026   |   Inventor(s): Sloan Breedy, Wishrawana Ratnayake, Mildred Acevedo-Duncan
Keywords(s): Cancer Treatment, Small Molecules
Category(s): Technology Classifications > Cancer, Technology Classifications > Chemistry, Technology Classifications > Medical > Oncology, Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals
Novel Therapy to Prevent Kidney Transplant Rejection
Advantages Targets root cause (cell death), not just immune suppression. Upstream Target: Blocks necroptosis before RIPK1 activation for earlier, more selective intervention. Novel mechanism outside the crowded RIPK1 space with strong IP positioning. Robust In Vivo Efficacy: ~50% ↓ graft injury; lead candidate shows ~65% ↓ creatinine...
Published: 6/22/2026   |   Updated: 1/12/2026   |   Inventor(s): Lei Wang, Zhigao Wang, Jianfeng Cai
Keywords(s): Organ Transplantation, Renal / Kidney
Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Chemistry, Technology Classifications > Medical > Therapeutics
Exogenous Acetate Formulations for Treating Alcohol Use Disorder and Withdrawal
Advantages Mechanistic Innovation: stabilizes brain energy metabolism and modulates adenosine signaling mechanisms not targeted by current addiction therapies. Targeted Brain Delivery: formulations enable effective acetate transport across the blood-brain barrier, (BBB) Controlled and sustained release Versatile Administration Routes: compatible...
Published: 7/13/2026   |   Updated: 9/30/2025   |   Inventor(s): Dominic D'Agostino
Keywords(s): Neuroscience, Pharmaceuticals
Category(s): Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Therapeutics, Technology Classifications > Chemistry, Technology Classifications > Medical > Biotechnology, Technology Classifications > Medical > Neuroscience
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