Search Results - paula+bickford

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Method of Treating Long-COVID Induced Neurologic Diseases
­Advantages: Method of preventing AD onset following severe COVID RNA Nano-carrier system carrying dual (brain and CNS)-targeted dendriplexes to target the brain and CNS Summary: COVID-19 is primarily a respiratory disease; however, neurological symptoms are also reported in a subpopulation of infected COVID-19 individuals. Complementary...
Published: 4/26/2024   |   Inventor(s): Subhra Mohapatra, Shyam Mohapatra, Paula Bickford, Laura Blair, Bala Chandran, Karthick Mayilsamy, Ryan Green
Keywords(s):  
Category(s): Technology Classifications > Medical > Neuroscience
sHSP22 Improves Cognition and Learning Independently of Tau
­Competitive Advantages Potential treatment for neurodegenerative diseases Hsp22 overexpression does not alter tau levels or tau phosphorylation status Hsp22 overexpression improved reversal spatial learning thus preserves learning and memory Summary Tau is a microtubule associated protein that has been linked to multiple neurodegenerative...
Published: 5/12/2023   |   Inventor(s): Laura Blair, Paula Bickford
Keywords(s): Medical Therapeutics Nonpharmaceutical Gene Therapy, Neurodegenerative Diseases
Category(s): Technology Classifications > Medical > Neuroscience, Technology Classifications > Medical
Treatment of Traumatic Brain Injury Using Adipocyte Derived Stem Cells Secreting Long Noncoding RNAs, NEAT1 and MALAT1, or ADSC Conditioned Media
­Competitive Advantages Improved cognitive performance Improved motor skills Prevents cortical and hippocampal damage Summary USF researchers have shown that lncRNAs secreted from adipocyte derived stem cells (ADSC) can improve certain motor, cognitive, and histological deficits related to TBI and other related diseases. Rats with induced...
Published: 8/26/2023   |   Inventor(s): Cesario Borlongan, Lisa Gould, Niketa Patel, Paula Bickford, Denise Cooper (VA)
Keywords(s):  
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Neuroscience
Treatment of Brain Injuries Using Exosomes from Adipose-Derived Stem Cells and Insulin
Competitive Advantages Promotes neuronal survival and regeneration Easy isolation in large quantities Minimal immune response Potential therapeutic application to treat brain injuries Summary USF researchers have demonstrate that hASC secrete factors which enhance the regeneration and survival of neurons. Exosomes from the hASC...
Published: 8/25/2023   |   Inventor(s): Niketa Patel, Paula Bickford
Keywords(s):  
Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Neuroscience