Search Results - yingyue+zhang

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Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications. Background Producing micro- and nanoparticles for pharmaceutical and...
Published: 1/7/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Safe Explicable Robot Planning
Background Effective human-robot interaction must be informed by human expectations and knowledge of the world, including how robots are expected to act/interact in various situations. However, knowledge about the robot may be inconsistent with the ground truth, which can result in the robot not meeting expectations, and the interaction integrity being...
Published: 12/13/2024   |   Inventor(s): Yu Zhang, Akkamahadevi Hanni, Andrew Boateng
Keywords(s):  
Category(s): Physical Science, Applied Technologies, Wireless & Networking, Artificial Intelligence/Machine Learning
3D-printed biosensors for high-sensitivity molecular detection
This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic
“Bio-Flex”: advanced formulation for sustainable stereolithography (SLA)
Background/problem Stereolithography (SLA) 3D printing has transformed the biomedical field with creation of highly accurate, patient-specific medical devices such as tissue scaffolds, implants, and surgical tools. This technology leverages computer-aided design and medical imaging data to produce structures with precise geometries at submicron scales....
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Anqi Lu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Therapeutics > Drug delivery
Thermal Control During Additive Manufacturing
THE CHALLENGE Additive manufacturing (AM) has emerged as a powerful tool within engineering. Many AM and coating processes rely on thermal input to soften or melt the materials involved in processing. However, this melting or softening typically results in a higher thermal gradient between deposited material and the workpiece, commonly resulting in...
Published: 12/20/2023   |   Inventor(s): Robert Griffiths, David Garcia, Hang Yu
Keywords(s):  
Category(s): EXPERIMENT--DO NOT USE, Technology Classifications > Additive Manufacturing
Targeted Therapy for Triple-Negative Breast Cancer
Breast cancer is the second leading cause of death in women and is the most common cancer among women worldwide. There are four main breast cancer subtypes, luminal A, luminal B, HER2-positive and triple-negative. Triple-negative breast cancer (TNBC) is highly invasive and has higher rates of metastasis and a worse prognosis. Metastasis of cancer cells...
Published: 9/12/2023   |   Inventor(s): Shengxi Chen, Xiaojiang Cui, Yi Zhang, Sidney Hecht
Keywords(s):  
Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Cancer, Cancer Therapeutics, Pharmaceuticals
FIBP Knockout Potentiates Therapeutic Effects of T-cell Based Therapies in Solid Tumors
Abstract: Despite recent breakthroughs in cancer immunotherapy, T-cell based therapies achieve limited efficacy in solid tumors. Immunosuppression, antigen escape and physical barriers to entry into solid tumors are issues faced. Identifying regulators in T-cell dysfunction remains challenging due to limitations of current screening platforms.  Using...
Published: 12/17/2024   |   Inventor(s): Peng Jiang, Yu Zhang
Keywords(s): adoptive cell therapy, Cancer Immunotherapy, cholesterol metabolism, Computational Model, FGF1 Intracellular Binding Protein, FIBP, Jiang, solid tumors, T-Cell based Therapy, T-Cell Resilience
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
Automated Flight Planning System for Urban Air Mobility
Advantages: AFPS uses advanced algorithms for airspace management and conflict resolution, ensuring safety in high-density Urban air mobility (UAM) environments. AFPS enhances UAM efficiency by optimizing airspace use and generating conflict-free flight paths. AFPS allows Providers of Service for UAM (PSU) to provide seamless airspace and traffic...
Published: 9/3/2024   |   Inventor(s): Yu Zhang
Keywords(s): Industrial Applications, Transportation
Category(s): Technology Classifications > Engineering > Drones, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Engineering > Sensors, Technology Classifications > Energy & Environment
Photonic FPGA platform to create arbitrary photonic devices by programming the device structure into the platform.
Background The development and design process for electronic integrated circuits is very intensive before a finalized chip design is sent to the chip fab. Most application-specific electronic integrated circuits require a prototyping process that can be accomplished with a field-programmable gate array (FPGA), an electronic circuit which can be reconfigured...
Published: 5/7/2024   |   Inventor(s): Jaime Cardenas Gonzalez, Yi Zhang, Marissa Granados-Baez
Keywords(s):  
Category(s): Nanotechnology
Imaging Inflammation using PET Radioligands that Target Translocator Protein 18?kDa with High Affinity Regardless of Genotype
This technology includes a group of radioligands that label inflammatory cells specifically, accurately, and across different genotypes and can be detected using Positron Emission Tomography (PET). The radioligands target the Translocator protein 18 kDa (TSPO) receptor which is present on the outer mitochondrial membrane and is involved in the production...
Published: 10/28/2024   |   Inventor(s): Robert Innis, Federico Da Settimo, Giorgio Stefancich, Sabrina Taliani, Sabrina Castellano, Claudia Martini, Yi Zhang, Victor Pike
Keywords(s): 18kDa, Emission, Genotype, Human, Listed LPM Fenn as of 4/15/2015, NA1XXX, Positron, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Quantifying/imaging, Radioligands, Regardless, tomography, TSPO, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XCXXXX, XFXXXX
Category(s): TherapeuticArea > Psychiatry/Mental Health, Application > Non-Medical Devices, TherapeuticArea > Neurology, Application > Software / Apps, Application > Diagnostics, Application > Medical Devices, Application > Research Materials
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