Search Results - small+cell+cancer

2 Results Sort By:
Temporal Transcriptomic Characterization of Small Cell Neuroendocrine Prostate Cancer (UCLA Case No. 2023-268)
The laboratory of Dr. Thomas Graeber at UCLA developed a novel in vivo model that can characterize mechanisms of the trans-differentiation of prostate cancer into small cell neuroendocrine cancer. BACKGROUND: Prostate cancer is one of the most common cancers among men worldwide, with an estimated 288,300 new cases in the U.S. last year. Among many...
Published: 7/10/2024   |   Inventor(s): Thomas Graeber
Keywords(s): neuroendocrine, Oncology, prostate cancer, small cell cancer, transdifferentiation
Category(s): Therapeutics > Oncology > Oncology (Small Molecules), Platforms > Diagnostic Platform Technologies
Human T-Cell Receptors Targeting Tumor-Enhanced Splicing Epitopes on HLA-A for Small Cell Carcinoma (UCLA Case Nos. 2023-117, 2020-817)
UCLA Researchers in the Department of Microbiology, Immunology, & Molecular Genetics have utilized their previously developed computational method (IRIS), to process and capture small cell carcinoma-specific RNA splicing events in small cell cancer. These events and associated epitopes were then used as the basis for generating new T cell receptors...
Published: 5/16/2024   |   Inventor(s): Owen Witte
Keywords(s): alternative splicing, Cancer, prostate cancer, RNA splicing, small cell, small cell cancer, small cell lung cancer, small cell prostate cancer, Targets And Assays
Category(s): Life Science Research Tools