Search Results - life+science+research+tools+%3e+antibodies

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Enzyme-Based Method for the Amplified Detection of Molecules on Particles (Case No. 2026-130)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel enzyme-based particle platform that enables amplified molecular detection in fully aqueous systems for sensitive, multiplexed analysis of low-abundance analytes. Background: The detection of molecules and determination of enzymatic activity are foundational across...
Published: 6/5/2026   |   Updated: 6/5/2026   |   Inventor(s): Alyssa Arnheim, Dino Di Carlo
Keywords(s): Antibody, Aptamers, Assay, barcode, Biomarker, Biosensor, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Drug Discovery, ELISA, enzyme functionalization, Enzyme Substrate (Biology), Flow Cytometry, Fluorescence, High-Throughput Screening, hydrogel, Immunoassay, Medical diagnostics, microparticles, Molecular Biology, multiplexed analysis, multiplexing, Nucleic Acids, protein, Signal-To-Noise Ratio
Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers, Platforms > Diagnostic Platform Technologies, Chemical > Chemical Sensors, Life Science Research Tools > Antibodies
Generation of Therapeutic Human Anti-Trop-2 Extracellular Domain Antibodies (UCLA Case No. 2026-026)
UCLA researchers from the Department of Molecular and Medical Pharmacology and the Department of Microbiology, Immunology and Molecular Genetics have developed a panel of human antibodies and chimeric antigen receptors targeting Trop-2, providing diagnostic and therapeutic resources for targeting Trop2-driven cancer. BACKGROUND: Trophoblast cell surface...
Published: 12/23/2025   |   Updated: 12/23/2025   |   Inventor(s): Tanya Stoyanova, Owen Witte
Keywords(s):  
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Antibodies, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
A Novel Lymphocyte Stimulation Assay To Quantify Immune Responses (UCLA Case No. 2022-079)
UCLA researchers in the Department of Medicine have developed lymphocyte stimulation assays to evaluate immune responses, supporting various clinical applications such as adjusting immunosuppressant drug levels and advancing COVID-19 vaccine development. The assay systems are reliable, cost-effective, and easy-to-perform, providing accurate assessments...
Published: 7/17/2025   |   Updated: 1/13/2025   |   Inventor(s): Yusaku Shino
Keywords(s): Antibody, biomarkers, cytokines, Immunity (Medical), immunosuppression, Organ Transplant
Category(s): Life Science Research Tools > Antibodies, Therapeutics > Immunology And Immunotherapy
Sarcospan Antibodies for Biomedical Application (UCLA Case No. 2024-082)
UCLA researchers in the Department of Integrative Biology and Physiology have developed a set of novel and highly specific sarcospan antibodies for use in basic and translational research. BACKGROUND: Sarcospan (SSPN) is a broadly expressed cell surface 25 kDa transmembrane protein. SSPN is critical for the function of adhesion complexes in skeletal...
Published: 11/17/2025   |   Updated: 5/8/2024   |   Inventor(s): Rachelle Crosbie, Ekaterina Mokhonova
Keywords(s): Antibodies, Becker muscular dystrophy, Duchenne muscular dystrophy, ELISA, immunoblotting, immunofluorescence, immunoprecipitation, musculoskeletal disorders, sarcospan
Category(s): Life Science Research Tools > Antibodies, Therapeutics > Musculoskeletal Disease
Cellphone-Based Micro-Plate Reader for Point-Of-Care ELISA Testing & High-Throughput and Automated Diagnosis of Antimicrobial Resistance
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a cost-effective cellphone-based micro-plate reader to rapidly perform antimicrobial susceptibility testing (AST) with >99% accuracy. Background: Immunoassays are biochemical tests that are conducted to measure the presence and concentration of...
Published: 7/17/2025   |   Updated: 7/7/2022   |   Inventor(s): Aydogan Ozcan, Dino Di Carlo, Steve Feng, Bingen Cortazar Unzaga, Brandon Berg, Haydar Ozkan, Omai Garner, Derek Kuochao Tseng
Keywords(s): Antibacterial, Antibiotic Resistance, Antibody, Artificial Intelligence, Bacteria, Drug Resistance, ELISA, High-Throughput Screening, Immunoassay, Nanotechnology, Optics, Photonics, Point Of Care, Smartphone
Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Diagnostic Markers, Optics & Photonics, Software & Algorithms > Artificial Intelligence & Machine Learning
2021-309-METHODS OF USING SHAPED PARTICLES IN FLOW CYTOMETERS FOR ASSAYS ON B CELLS AND T CELLS
Summary: UCLA researchers in the Department of Bioengineering have developed a platform to sort single cells based on their secreted product at high throughput using commonly accessible lab infrastructure, i.e., flow cytometers. Background: Techniques to sort single cells based on secreted products have the potential to accelerate the development...
Published: 7/17/2025   |   Updated: 3/21/2022   |   Inventor(s): Dino Di Carlo, Joseph de Rutte, Robert Dimatteo, Maani Archang, Robert Damoiseaux, Doyeon Koo
Keywords(s): Antibody, B Cell, Bioassay, Cell Counting/Imaging, Cellular Differentiation, Cytometry, Flow Cytometry, Fluorescence, Hybridoma Technology, Secretory Component, T Cell, Targets And Assays
Category(s): Life Science Research Tools, Life Science Research Tools > Antibodies, Life Science Research Tools > Cell Lines, Life Science Research Tools > Research Methods, Life Science Research Tools > Other Reagents, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies
System and Methods for Amplified Detection of Molecules on Microparticles (Case No. 2021-002)
Summary: UCLA researchers in the Department of Bioengineering have developed a system to build immunocomplexes, generate and accumulate amplified signals, and perform the signal readout of a digital ELISA using standard benchtop instruments and techniques. Background: Digital ELISA allows for the detection and measurement of protein biomarkers at...
Published: 6/5/2026   |   Updated: 12/9/2020   |   Inventor(s): Dino Di Carlo, Yilian Wang, Vishwesh Nilesh Shah
Keywords(s):  
Category(s): Life Science Research Tools > Research Methods, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Antibodies, Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies
Augmentating T-Cell Activation by Oscillatory Forces and Engineered Antigen-Presenting Cells (UCLA Case No. 2019-726)
UCLA researchers in the Department of Pediatrics have developed a suite of novel spherical aAPCs of varying sizes and densities, that can be coupled with an oscillatory stimulus to promote efficient T cell activation: offering the possibility to aptly engineer T cells for a variety of clinical and experimental needs. BACKGROUND:T cells circulate throughout...
Published: 7/31/2025   |   Updated: 8/7/2020   |   Inventor(s): Manish Butte, Fatemeh Sadat Majedi
Keywords(s): Immunology, Immunotherapy, Life Science Research Tools, Oncology, Oncology Immunotherapy
Category(s): Life Science Research Tools > Antibodies, Life Science Research Tools > Research Methods, Diagnostic Markers > Immunology, Therapeutics > Oncology > Oncology Immunotherapy
2011-464 Polyclonal Antibody Recognizing the Human RIN2 Protein
Innovation RIN2 is a RAS effector protein with guanine nucleotide exchange factor (GEF) activity for RAB5 family GTPases. RIN2 is part of a cerebral cavernous malformations (CCM) signaling complex implicated in sporadic or inherited vascular lesions of the central nervous system. Additionally, RIN2 deficiencies are linked to the human connective tissue...
Published: 7/10/2025   |   Updated: 1/16/2020   |   Inventor(s):  
Keywords(s):  
Category(s): Life Science Research Tools > Antibodies
2011-418 Novel Monoclonal Antibodies against Neospora Caninum
Summary UCLA researchers have developed a large number of highly specific monoclonal antibodies against the intracellular parasite Neospora caninum that can be used for diagnostic or research purposes.Background Apicomplexan parasites cause a wide array of diseases of medical and veterinary importance including malaria (Plasmodium spp.), toxoplasmosis...
Published: 7/10/2025   |   Updated: 1/16/2020   |   Inventor(s):  
Keywords(s):  
Category(s): Life Science Research Tools > Antibodies
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