Search Results - covid-19

21 Results

Sort By:

Viral-Targeted Nanostructured Drug (VTND) Platform

The outbreak of COVID-19 and subsequent mutant variants has caused millions of deaths and severe acute respiratory illness worldwide. Therapeutics such as monoclonal antibodies, small molecule drugs inhibiting viral replication and immune modulators suppressing hyperinflammation have shown promise, but each comes with limitations including viral variant...

Published: 11/21/2023 | Inventor(s): Hao Yan, Yang Xu, Deeksha Satyabola, Yize (Henry) Li, Abhay Prasad

Keywords(s):

Category(s): COVID-19, SARS-CoV-2, Coronavirus, Advanced Materials/Nanotechnology, Life Science (All LS Techs), Pharmaceuticals, Non-Cancer Therapeutics

Pathogen Molecular Detection Platform

Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Published: 1/31/2024 | Inventor(s): Alexander Green, Keith Pardee, Margot Karlikow, Kaiyue Wu, Masoud Norouzi

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools, COVID-19, Coronavirus, SARS-CoV-2

Monoclonal Antibodies Against SARS-CoV-2 Variants

Although the world has returned to a state of relative normalcy, SARS-CoV-2 infections continue to persist worldwide, and immune evasive variants continue to emerge. Monoclonal antibodies (mAbs) are often first in line therapy for SARS-CoV-2 infections, but most have lost utility against the Omicron variant and its subvariants. One mAb cocktail, Evusheld,...

Published: 8/7/2023 | Inventor(s): Qiang Chen, Haiyan Sun, Collin Jugler

Keywords(s):

Category(s): Coronavirus, COVID-19, Life Science (All LS Techs), Protein/Pharma Production in Plants, SARS-CoV-2, Non-Cancer Therapeutics

Platform for High-Throughput Quantification of Neutralizing Antibodies

In the past 10 years, there have been many new viral pathogens which have emerged as major public health threats, including Ebola virus, SARS-CoV, Zika virus and most recently SARS-CoV-2. Quantitative measurement of neutralizing antibodies (nAbs) is important for determining sterilizing immunity as well as evaluating effectiveness of vaccines and...

Published: 8/9/2023 | Inventor(s): Chao Wang, MD Ashif Ikbal, Seyedsina Mirjalili

Keywords(s):

Category(s): Bioanalytical Assays, Chemistries & Devices, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors

Prediction Algorithm for MHC-bound Peptides & SARS-CoV-2 Peptides for Vaccines

T cell immunity is a fundamental component of the immune response to infections, cancer, and autoimmunity and is strongly impacted by polymorphisms in major histocompatibility complex (MHC) protein sequences. In particular, allelic MHC-I protein variants have been shown to influence patient outcomes to various viral infections, including SARS-CoV. While...

Published: 3/10/2023 | Inventor(s): Karen Anderson, Abhishek Singharoy, Eric Wilson

Keywords(s):

Category(s): Computing & Information Technology, Coronavirus, COVID-19, Life Science (All LS Techs), Pharmaceuticals, Vaccines/Antimicrobials, SARS-CoV-2, Proteomic Assays/Reagents/Tools, Intelligence & Security

Cannabinoid Acid Crystalline Forms

Cannabinoid acids are a class of natural compounds that are commonly isolated from the plant C. sativa, which, when decarboxylated, produce the most widely known and used cannabinoids. Both naturally extracted as well as synthetically produced cannabinoids have therapeutic potential, as evidenced by FDA approval of a synthetic formulation of THC and...

Published: 5/19/2023 | Inventor(s): Jeffery Yarger, Stephen Davidowski, Michael Seth

Keywords(s):

Category(s): COVID-19, Coronavirus, Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals, SARS-CoV-2, Advanced Materials/Nanotechnology

Cough Audio COVID-19 Detection Via Deep Neural Network with Combined Cross Entropy and Focal Loss

Background With the outbreak of COVID-19 caused by the coronavirus SARS-CoV-2, the severity of infection and associated fatality rates motivate the exploration for rapid and reliable screening approaches. Although reverse transcriptase-polymerase chain reaction (RT-PCR) testing is commonly adopted, coughing sounds have been found to reveal useful...

Published: 2/23/2023 | Inventor(s): Sunil Rao, Vivek Sivaraman Narayanaswamy, Michael Esposito, Andreas Spanias

Keywords(s): COVID-19, Networks, IT, Software and Communication

Category(s): Intelligence & Security, Physical Science, Computing & Information Technology, COVID-19, Coronavirus, Medical Diagnostics/Sensors

Method for Producing Self-Replicating, Nucleic Acid-Loaded Virus-Like Particles

Vaccines are an essential tool in preventing and controlling many diseases. Most approved vaccines are inactivated or live attenuated type, however, alternative platforms like mRNA and virus-like particles (VLPs) are being increasingly explored and approved because they generate potent immune responses with great safety profiles. VLPs are particularly...

Published: 2/23/2023 | Inventor(s): Qiang Chen, Haiyan Sun, Collin Jugler, Huafang Lai

Keywords(s):

Category(s): Coronavirus, COVID-19, SARS-CoV-2, Vaccines/Antimicrobials, Pharmaceuticals, Life Science (All LS Techs), Genomic Assays/Reagents/Tools

Simple, Portable, Low-cost, Viral Antigen Detection Method

Recent infectious diseases, such as SARS-CoV-2, have caused massive and widespread global health and economic problems. One of the most effective tools in the early stages of a disease outbreak is testing and isolation of the infected. However, it takes time to develop a new diagnostic, particularly with novel pathogens. By the time a new test...

Published: 2/23/2023 | Inventor(s): Chao Wang, Liangcai Gu, Xiahui Chen, Shoukai Kang, MD Ashif Ikbal, Zhi Zhao

Keywords(s):

Category(s): Coronavirus, COVID-19, SARS-CoV-2, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices

Assay for Detecting Viral Pathogens

As we make our way through the third year of the global pandemic, one thing is abundantly clear, COVID testing is just as important now as it was in the beginning. But not all testing is created equal. PCR is highly sensitive; however, it requires well-trained personnel and expensive equipment, prohibiting home use and limiting use in areas with...

Published: 2/23/2023 | Inventor(s): Alexander Green, Duo Ma

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, COVID-19, Coronavirus, SARS-CoV-2, Genomic Assays/Reagents/Tools, Medical Diagnostics/Sensors, Life Science (All LS Techs)

1 2 3