Search Results - eric+wilson

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HLA-Inception: MHC-Peptide Binding Prediction
Major histocompatibility complex class I (MHC-I) molecules are principal components of immune recognition. Peptide binding to MHC-I molecules is necessary for antigen presentation and T cell recognition. Understanding and predicting MHC-I binding has great utility in T cell therapies, vaccine development and treatment of complex human diseases. Unfortunately,...
Published: 10/10/2024   |   Inventor(s): Eric Wilson, Abhishek Singharoy, Karen Anderson, John Cava
Keywords(s):  
Category(s): Applied Technologies, Computing & Information Technology, Cancer, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Prediction Algorithm for MHC-bound Peptides & SARS-CoV-2 Peptides for Vaccines
T cell immunity is a fundamental component of the immune response to infections, cancer, and autoimmunity and is strongly impacted by polymorphisms in major histocompatibility complex (MHC) protein sequences. In particular, allelic MHC-I protein variants have been shown to influence patient outcomes to various viral infections, including SARS-CoV. While...
Published: 3/10/2023   |   Inventor(s): Karen Anderson, Abhishek Singharoy, Eric Wilson
Keywords(s):  
Category(s): Computing & Information Technology, Coronavirus, COVID-19, Life Science (All LS Techs), Pharmaceuticals, Vaccines/Antimicrobials, SARS-CoV-2, Proteomic Assays/Reagents/Tools, Intelligence & Security