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Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Published: 1/31/2024 | Inventor(s): Alexander Green, Keith Pardee, Margot Karlikow, Kaiyue Wu, Masoud Norouzi

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools, COVID-19, Coronavirus, SARS-CoV-2

Pathogen Molecular Detection Platform

Published: 10/17/2023 | Inventor(s): Alexander Green, Duo Ma

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors

CRISPR-Cas/Transcription Factor-Based Assay for Detection of Molecular Analytes

The ability to detect small molecules and other chemical analytes is important for many applications from assessing drinking water to monitoring effluents and ensuring food and drinks are safe to consume. While synthetic biology has enabled the development of molecular biosensors, such as transcription factors, to detect small molecules, they rely on...

Published: 10/26/2023 | Inventor(s): Alexander Green, Soma Chaudhary, Kirstie Swingle

Keywords(s):

Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Life Science (All LS Techs), Medical Diagnostics/Sensors

Assay for Detecting Viral Pathogens

As we make our way through the third year of the global pandemic, one thing is abundantly clear, COVID testing is just as important now as it was in the beginning. But not all testing is created equal. PCR is highly sensitive; however, it requires well-trained personnel and expensive equipment, prohibiting home use and limiting use in areas with...

Published: 2/23/2023 | Inventor(s): Alexander Green, Duo Ma

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, COVID-19, Coronavirus, SARS-CoV-2, Genomic Assays/Reagents/Tools, Medical Diagnostics/Sensors, Life Science (All LS Techs)

Rapid and Low-Cost Nucleic Acid Detection Platform

Because genetic information is used in pathogen detection, human genotyping, determining and detecting mutations which cause disease and for monitoring and treatment of infectious diseases, it is imperative that new methods for detecting nucleic acids are developed that are rapid, inexpensive and easy to implement. PCR-based methods for detecting nucleic...

Published: 2/23/2023 | Inventor(s): Alexander Green, Kaiyue Wu

Keywords(s):

Category(s): Coronavirus, COVID-19, SARS-CoV-2, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs)

Pathogen Molecular Detection Platform

Published: 2/23/2023 | Inventor(s): Qi Zhang, Xiao Wang, Alexander Green, Duo Ma, Fuqing Wu, Kylie Standage-Beier, Xingwen Chen

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors

Pathogen Molecular Detection Platform

Published: 2/23/2023 | Inventor(s): Alexander Green, Fan Hong, Soma Chaudhary, Anli Tang, Hao Yan

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools

Artificial Ribosomes for Fully Programmable Synthesis of Nonribosomal Bioactive Compounds

Nonribosomal peptides are bioactive and highly diverse compounds, usually produced by microorganisms, which comprise some of the most important drugs in use today, including antimicrobials, immunosuppressants and anticancer compounds. These compounds are synthesized by nonribosomal peptide synthetases (NRPSs) which can incorporate over 300 different...

Published: 2/23/2023 | Inventor(s): Alexander Green

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals

Low-Cost Detection of Norovirus and other Infectious Agents

Noroviruses are the leading cause of gastroenteritis and foodborne illness, affecting millions and causing nearly $60 billion in societal costs each year. They are highly contagious and persist in the environment, resulting in frequent outbreaks in healthcare facilities, hospitals, schools and cruise ships. Further, these viruses can lead to severe...

Published: 2/23/2023 | Inventor(s): Alexander Green, Duo Ma, Luhui Shen, Chris Diehnelt

Keywords(s):

Rapid Low-Cost Detection of Valley Fever

Valley Fever (VF) or coccidioidomycosis is a systemic fungal infection that is endemic to the Southwestern United States with the highest frequency occurring in Arizona. Studies suggest that as few as 10 inhaled spores are sufficient to cause an infection. Of those who become infected, 40% experience flu-like symptoms or develop skin rashes, fatigue,...

Published: 2/23/2023 | Inventor(s): Alexander Green

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools

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