Search Results - sars-cov-2

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Computational Method to Identify Mutational Epistasis in Proteins

Invention Description Viral evolution, particularly rapid viral evolution, can lead to the emergence of variants of concern. In order to develop effective antiviral strategies, it is essential to understand the molecular mechanisms driving these adaptations. Some research has focused on identifying adaptive mutations and how they impact protein structure...

Published: 1/12/2026 | Inventor(s): Paul Campitelli, Nicholas Ose, Tushar Modi, Ismail Can Kazan, Sefika Banu Ozkan

Keywords(s):

Category(s): Vaccines/Antimicrobials, Life Science (All LS Techs), Computing & Information Technology, Artificial Intelligence/Machine Learning, COVID-19, SARS-CoV-2, Coronavirus

Integrated Microfluid Cartridge for POC Biofluid Diagnostics

Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...

Published: 1/6/2026 | Inventor(s): Vi Nguyen, Clifford Anderson, Jennifer Blain Christen

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Coronavirus, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care, SARS-CoV-2

Pathogen Molecular Detection Platform

Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...

Published: 2/13/2025 | Inventor(s): Alexander Green, Keith Pardee, Margot Karlikow, Kaiyue Wu, Masoud Norouzi

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools, COVID-19, Coronavirus, SARS-CoV-2

Monoclonal Antibodies Against SARS-CoV-2 Variants

Although the world has returned to a state of relative normalcy, SARS-CoV-2 infections continue to persist worldwide, and immune evasive variants continue to emerge. Monoclonal antibodies (mAbs) are often first in line therapy for SARS-CoV-2 infections, but most have lost utility against the Omicron variant and its subvariants. One mAb cocktail, Evusheld,...

Published: 2/13/2025 | Inventor(s): Qiang Chen, Haiyan Sun, Collin Jugler

Keywords(s):

Category(s): Coronavirus, COVID-19, Life Science (All LS Techs), Protein/Pharma Production in Plants, SARS-CoV-2, Non-Cancer Therapeutics

Prediction Algorithm for MHC-bound Peptides & SARS-CoV-2 Peptides for Vaccines

T cell immunity is a fundamental component of the immune response to infections, cancer, and autoimmunity and is strongly impacted by polymorphisms in major histocompatibility complex (MHC) protein sequences. In particular, allelic MHC-I protein variants have been shown to influence patient outcomes to various viral infections, including SARS-CoV. While...

Published: 2/13/2025 | Inventor(s): Karen Anderson, Abhishek Singharoy, Eric Wilson

Keywords(s):

Category(s): Computing & Information Technology, Coronavirus, COVID-19, Life Science (All LS Techs), Pharmaceuticals, Vaccines/Antimicrobials, SARS-CoV-2, Proteomic Assays/Reagents/Tools, Intelligence & Security

Cannabinoid Acid Crystalline Forms

Cannabinoid acids are a class of natural compounds that are commonly isolated from the plant C. sativa, which, when decarboxylated, produce the most widely known and used cannabinoids. Both naturally extracted as well as synthetically produced cannabinoids have therapeutic potential, as evidenced by FDA approval of a synthetic formulation of THC and...

Published: 6/29/2025 | Inventor(s): Jeffery Yarger, Stephen Davidowski, Michael Seth

Keywords(s):

Category(s): COVID-19, Coronavirus, Life Science (All LS Techs), Non-Cancer Therapeutics, Pharmaceuticals, SARS-CoV-2, Advanced Materials/Nanotechnology

Method for Producing Self-Replicating, Nucleic Acid-Loaded Virus-Like Particles

Vaccines are an essential tool in preventing and controlling many diseases. Most approved vaccines are inactivated or live attenuated type, however, alternative platforms like mRNA and virus-like particles (VLPs) are being increasingly explored and approved because they generate potent immune responses with great safety profiles. VLPs are particularly...

Published: 2/13/2025 | Inventor(s): Qiang Chen, Haiyan Sun, Collin Jugler, Huafang Lai

Keywords(s):

Category(s): Coronavirus, COVID-19, SARS-CoV-2, Vaccines/Antimicrobials, Pharmaceuticals, Life Science (All LS Techs), Genomic Assays/Reagents/Tools

Simple, Portable, Low-cost, Viral Antigen Detection Method

Recent infectious diseases, such as SARS-CoV-2, have caused massive and widespread global health and economic problems. One of the most effective tools in the early stages of a disease outbreak is testing and isolation of the infected. However, it takes time to develop a new diagnostic, particularly with novel pathogens. By the time a new test...

Published: 2/13/2025 | Inventor(s): Chao Wang, Liangcai Gu, Xiahui Chen, Shoukai Kang, MD Ashif Ikbal, Zhi Zhao

Keywords(s):

Category(s): Coronavirus, COVID-19, SARS-CoV-2, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices

Assay for Detecting Viral Pathogens

As we make our way through the third year of the global pandemic, one thing is abundantly clear, COVID testing is just as important now as it was in the beginning. But not all testing is created equal. PCR is highly sensitive; however, it requires well-trained personnel and expensive equipment, prohibiting home use and limiting use in areas with...

Published: 2/13/2025 | Inventor(s): Alexander Green, Duo Ma

Keywords(s):

Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, COVID-19, Coronavirus, SARS-CoV-2, Genomic Assays/Reagents/Tools, Medical Diagnostics/Sensors, Life Science (All LS Techs)

UV-C Wavelength Side-Emitting Optical Fibers Enabled by Surface Texturing

Background Although chlorine remains one of the most widely used water disinfectants throughout the world, the toxicity of the chemical itself and of its by-products poses significant health risks. Non-chemical disinfectants such as ultraviolet (UV) irradiation has been an attractive alternative and is gaining acceptance in both large-scale and...

Published: 2/13/2025 | Inventor(s): Paul Westerhoff, Zhe Zhao, Nora Shapiro

Keywords(s):

Category(s): COVID-19, Coronavirus, SARS-CoV-2, Physical Science, Manufacturing/Construction/Mechanical, Environmental Remediation/Wastewater Treatment

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