Search Results - kaushal+rege

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Wound Healing Compositions
­Dermal wound healing is a complex and dynamic process involving the highly regulated coordination of diverse signaling events. Dysregulation during any of the stages of healing can result in scarring and tissue disruption increasing the risk of morbidity and mortality. It is estimated that chronic wounds affect more than 6 million people in the...
Published: 2/23/2023   |   Inventor(s): Jordan Yaron, Kaushal Rege
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Life Science (All LS Techs)
Colorometric Hydrogel based Nanosensor for Detection of Therapeutic Levels of Ionizing Radiation
Radiotherapy is a common medical procedure, especially for the treatment of cancers such as head and neck, breast prostate, lung and rectum. It is a complex process aimed at maximizing delivery of the planned dose to the tumor sites while minimizing unnecessary radiation to healthy tissues. Today, radiotherapy procedures make use of image guidance and...
Published: 2/23/2023   |   Inventor(s): Kaushal Rege, Karthik Subramaniam Pushpavanam, Stephen Sapareto, John Chang
Keywords(s): Nanomaterials
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Environmental, Life Science (All LS Techs), Medical Diagnostics/Sensors, Intelligence & Security
Encapsulation Strategy for Creating Engineered 3D Cellular Models
Cell culture is a fundamental research tool for countless biological applications from drug discovery to cancer research and regenerative medicine. While two-dimensional (2D) cell culture is ubiquitous in research settings, it fails to adequately consider the natural three-dimensional (3D) microenvironment of cells. As newer and better 3D cell culture...
Published: 2/23/2023   |   Inventor(s): Rajeshwar Nitiyanandan, Tanya Nanda, Kaushal Rege
Keywords(s): Drug Screening, Regenerative Medicine
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Cancer Therapeutics, Life Science (All LS Techs), Medical Devices, Non-Cancer Therapeutics, Pharmaceuticals
Bioactive Dressing for Accelerated Wound Healing
Wound healing is a complex but organized process involving hemostasis, inflammation, new tissue generation and remodeling. However, when wounds cover a large surface area, become infected, or occur in diabetic or elderly patients, wound healing can be delayed and lead to chronic ulcerations and other complications. Despite the abundance of wound management...
Published: 2/23/2023   |   Inventor(s): Kaushal Rege, Deepanjan Ghosh
Keywords(s):  
Category(s): Life Science (All LS Techs), Biomaterials, Advanced Materials/Nanotechnology, Medical Devices
Smart Materials for Repairing Injured Nerves
Peripheral nerve injuries can affect sensation, movement and motor functions, significantly impacting a patient’s quality of life. Surgical interventions, such as approximation or attachment, are often required to treat such injuries. However, tissue adhesives and sealants do not provide adequate mechanical support and suffer from low adhesion...
Published: 11/27/2023   |   Inventor(s): Kaushal Rege, Russell Urie, Inam (Maryam) Ridha, Pelagia Kouloumberis, Shelley Noland
Keywords(s):  
Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Biomaterials, Medical Devices
Modified Aminoglycoside based polymers
Gene delivery systems include both viral and non-viral carriers. The use of cationic polymers, such as aminoglycosides, as non-viral carriers has seen increased interest mainly due to their ease of synthesis, robust nature and gene delivery efficacies. Unfortunately, cationic polymers are also known for low gene expression and toxicity. Because of their...
Published: 2/23/2023   |   Inventor(s): Kaushal Rege, Bhavani Miryala, Thrimoorthy Potta
Keywords(s):  
Category(s): Biomaterials, Cancer Therapeutics, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Vectors/Constructs/Plasmids
Aminoglycoside-based Resins and Their Applications
Aminoglycoside antibiotics are known to prevent growth of gram-negative bacteria by inhibiting protein synthesis. Aminoglycosides possess biocompatible sugar groups as well as multiple amines in the same molecule. Their tenability and natural affinity towards nucleic acids makes them excellent candidates for generating diverse resins for multiple applications...
Published: 2/23/2023   |   Inventor(s): Kaushal Rege, Taraka Sai Pavan Grandhi, Thrimoorthy Potta
Keywords(s): Bio-Technology, Drug Screening, Environmental, Materials and Electronics, Therapeutics
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Biomaterials, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs)
Devices for High Throughput Manufacture of 3D Macroporous Polymeric Scaffolds
3D macroporous gels/polymeric monoliths are finding increased utility in many applications including plasmid DNA binding, tissue engineering, tumor modeling, 3D cell cultures and studies, and so on. However, creating these gels is cumbersome, requires technical skill and is limited to smaller quantities. There is a need to be able to easily create multiple...
Published: 2/23/2023   |   Inventor(s): Kaushal Rege, Taraka Sai Pavan Grandhi, Andrew Dobos
Keywords(s): Bio-Technology, Drug Screening, Environmental, Materials and Electronics, Mechanical and Manufacturing, Medical Devices and Imaging, Therapeutics
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices
Nanosensors for Dosimetry of Therapeutic Levels of Ionizing Radiation
Radiotherapy is a common medical procedure, especially for the treatment of cancers such as head and neck, breast prostate, lung and rectum. It is a complex process aimed at maximizing delivery of the planned dose to the tumor sites while minimizing unnecessary radiation to healthy tissues. Today, radiotherapy procedures make use of image guidance and...
Published: 8/5/2024   |   Inventor(s): Kaushal Rege, Karthik Subramaniam Pushpavanam, Eshwaran Narayanan, John Chang, Stephen Sapareto
Keywords(s): Bio-Technology, Environmental, Materials and Electronics, Medical Devices and Imaging, Therapeutics
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Environmental, Life Science (All LS Techs), Medical Diagnostics/Sensors, Intelligence & Security
Novel Methylation Specific DNA Binding Resins
Cancer is one of the biggest challenges facing the present healthcare community. Cancer diagnostics play a very important role in detecting the onset of disease and enabling continuous monitoring of patients in remission. Early detection of disease occurrence, progression and/or recurrence can significantly increase the chances of patient survival....
Published: 2/23/2023   |   Inventor(s): Kaushal Rege, Taraka Sai Pavan Grandhi, Sudhakar Godeshala, Kevin Lin
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Advanced Materials/Nanotechnology, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Diagnostic Assays/Devices
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