Search Results - mengmeng+zheng

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Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR for Cancer Treatment
­Advantages: Novel cyclic γ-AA peptide (M-2-5) effectively binds with EGFR and inhibits tumor growth in an A549 lung cancer xenograft model. M-2-5 interferes with EGFR-EGF binding, prevents EGFR phosphorylation, and suppresses cancer cell proliferation and migration. Targets the extracellular domain of EGFR with high affinity and specificity....
Published: 7/29/2024   |   Inventor(s): Jianfeng Cai, Mengmeng Zheng
Keywords(s):  
Category(s): Technology Classifications > Cancer
Peptidomimetic-Based Antibody Surrogate for HER2
­Advantages: High affinity for HER2 and inhibits downstream signaling Potent anti-tumor effects Small molecular weight Resistant to proteolysis Summary: Current HER2-targeted therapies, including monoclonal antibody trastuzumab, are hindered by high cost of production, large molecular weight, and susceptibility to degradation. A novel...
Published: 8/24/2023   |   Inventor(s): Jianfeng Cai, Mengmeng Zheng
Keywords(s): Antibodies, Antiviral Therapeutics, Cancer, Peptides
Category(s): Technology Classifications > Cancer > Cancer Treatment Breast Cancer
Identification of Women Who May or May Not Benefit From Certain Invention for Preventing Preterm Birth Based On Bacterial Taxa In The Cervix
 
Published: 5/25/2020   |   Inventor(s): Siu Chung Stephen Chim, Keun Young Lee, Ka Wing Wong, Meng Meng, Tak Yeung Leung
Keywords(s):  
Category(s): Diagnostics