Search Results - -method

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Nanostructuring of Polymers and Polymer Composites Using Pressure
A novel procedure for nanostructuring of polymer surfaces for medical implants to resist bacterial adhesion and biofilm formation Institute Reference: INV-14027 Background So far in the medical device community, several techniques have been used to improve the cytocompatibility of polymer surfaces by chemical or physical techniques for tissue engineering...
Published: 9/10/2024   |   Inventor(s): Thomas Webster
Keywords(s): Method, Nanotechnology
Category(s): -Method, -Nanotechnology
Antibody-based Rolling Circle Amplification for COVID-19 Detection by a Colorimetry
INV-21038 Background Viruses are conventionally detected by RT-PCR. This method requires long analysis time, highly trained professionals, and often shows non-specific characteristics. Antigens and antibodies (Ag/Ab) are commonly used for fluorescence immunoassay. However, the fluorescent signal from the individual fluorescent molecule attached...
Published: 9/10/2024   |   Inventor(s): Ji Won Lim, Tania Konry
Keywords(s): Analytical Chemistry, COVID-19, Detection, Diagnostics
Category(s): -Method, Technology Classifications > 1. Life Science, Diagnostics, Chemistry
Deep field penetration in transcranial magnetic stimulation (TMS) via magnetic flux concentrator and strategic excitation coil placement
INV-14084 Background Transcranial Magnetic Stimulation (TMS) is a method for noninvasive, non-contact stimulation of neurons in the brain by magnetic induction of electrical currents. The TMS devices currently available on the market provide superficial stimulation due to the rapid attenuation of the field. Deeper penetration can only be achieved...
Published: 9/10/2024   |   Inventor(s): Vincent Harris, Francesca Scire Scappuzzo, Parisa Andalib
Keywords(s): Health, Healthcare Innovation, Medical Device
Category(s): -Health, -Method, Technology Classifications > 1. Life Science > Medical Devices
New Method for Discovery of Bioactive Molecules
INV-20024 Background Microbes are a foundation of the discovery of bioactive molecules because they produce an enormous variety of secondary metabolites, some with desirable activities ranging from antibiotics to anti-inflammatory to anticancer to industrial enzymes. The advent of next-generation sequencing technologies uncovered that microbial genomes...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s): Antimicrobial, Biomolecules, Cancer, Drugs, Microbiology
Category(s): -Method, Antimicrobial, Technology Classifications > 1. Life Science > Gene sequencing, Technology Classifications > 1. Life Science > Drug Discovery
Live Single-Cell Bioassay in Micro-droplets
INV-17085 Background The outcome of many pathological diseases including cancer is determined by types (functional and phenotypical) of immune cells present in the body. The existence of tremendous heterogeneity in these cells influences the time taken for the immune reaction and an individual’s ability to recover from the illness. Hence, assessing...
Published: 9/10/2024   |   Inventor(s): Tania Konry, Saheli Sarkar, Pooja Sabhachandani
Keywords(s):  
Category(s): -Method, -Cancer, Technology Classifications > 1. Life Science, Diagnostics
A Bilayer Nanomesh Based Electrophysiological Microelectrode
INV-18009 Background Mapping electrical activity is critical in neuroscience, cardiac physiology, and muscle contraction, among others. The stakes are perhaps the highest in brain mapping, where it is critical to measure fast currents from neurons, while simultaneously imaging the cell morphology. There are currently no tools that can provide both...
Published: 9/10/2024   |   Inventor(s): Hui Fang, Yi Qiang, Kyung Jin Seo, Michela Fagiolini, Pietro Artoni
Keywords(s):  
Category(s): -Materials, -Method, Technology Classifications > 2. Physical Science
Methods and Compositions for Ex Vivo Generation of Developmentally Competent Eggs from Germline Cells Using Autologous Cell Systems
INV-14038 Background According to the latest CDC records, about 12% of women aged 15-44 are suffering from some sorts of infertility; yet, less than 2% of infertile couples actually undergo assisted reproductive therapy (ART). Besides the prohibitive cost of infertility treatments, many factors, including diminished population of immature egg cells...
Published: 9/10/2024   |   Inventor(s): Jonathan Tilly, Dori Woods
Keywords(s): Biotech, Materials, Medical Device, Method
Category(s): -Biology, -Materials, -Method, Technology Classifications > 1. Life Science > Medical Devices
Non-noble Metal Based ODC Cathodes for Chlorine Evolution Processes
INV-13048 Background Use of “depolarizers” in electrolytic reactions helps lower input electrical energy in electrochemical processes. For example, in batteries depolarizers help prevent buildup of hydrogen gas bubbles thereby preventing the voltage, and thereby current, from being reduced. Among the known depolarizers, including sulfur...
Published: 9/10/2024   |   Inventor(s): Sanjeev Mukerjee, Urszula Tylus
Keywords(s): Catalyst, Chemistry, Environment
Category(s): -Catalyst, -Chemistry, -Method, Technology Classifications > 2. Physical Science > Environmental/Clean tech