Search Results - kyung+jin+seo

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Inhibition of T Cell Differentiation and Senescence by Overexpression of Transcription Factor c-Myb
Abstract: Adoptive Cell Therapy (ACT) is a promising technique that uses a patient's own T cells to treat cancer. The process requires removing and engineering a patient's T cells to express a chimeric antigen receptor (CAR) or T cell receptor (TCR) that targets a specific cancer antigen. When the modified T cells are reintroduced into the patient,...
Published: 4/8/2024   |   Inventor(s): Sanjivan Gautam, Yun Ji, Luca Gattinoni
Keywords(s): act, Adoptive Cell Transfer, CANCER, CAR, chimeric antigen receptor, Gattinoni, Immunotherapy, Infectious Disease, Stem Cell, T cell, T Cell Receptor, TCR
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
Overexpression of Phf19 on T Cells Enhances Therapeutic Effects of T Cell-Based Therapies (such as Chimeric Antigen Receptor [CAR] Therapies)
Abstract: T cell-based immunotherapy (such as CAR therapies) is a promising approach for the treatment of several cancers. However, T cells currently employed for various T cell-based immunotherapies are usually senescent and terminally differentiated leading to poor proliferative and survival capacity, limiting their therapeutic effectiveness once...
Published: 4/8/2024   |   Inventor(s): Yun Ji, Luca Gattinoni
Keywords(s): CAR-T Therapy, CD8, chimeric antigen receptor, Gattinoni, Phf19, T cell
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics
A Bilayer Nanomesh Based Electrophysiological Microelectrode
INV-18009 Background Mapping electrical activity is critical in neuroscience, cardiac physiology, and muscle contraction, among others. The stakes are perhaps the highest in brain mapping, where it is critical to measure fast currents from neurons, while simultaneously imaging the cell morphology. There are currently no tools that can provide both...
Published: 9/10/2024   |   Inventor(s): Hui Fang, Yi Qiang, Kyung Jin Seo, Michela Fagiolini, Pietro Artoni
Keywords(s):  
Category(s): -Materials, -Method, Technology Classifications > 2. Physical Science
Magnetic Matrix Connector for High density, Soft Neural Interface
INV-20017 Background In this invention, the Magnetic Matrix connector (MagMatrix) for high-density, soft neural interfaces such as neural microelectrode arrays (MEA) is used. In order to interface with the soft devices and rigid measuring electronics, a connector is necessarily required. Currently, there are several available strategies such as...
Published: 9/10/2024   |   Inventor(s): Hui Fang, Yi Qiang, Xun Han, Kyung Jin Seo
Keywords(s): Circuits, Electronics, Nanotechnology
Category(s): -Magnetics