Search Results - tania+konry

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Mitochondria transplantation in immune effector cells using droplet microfluidics and a sorter device for activating, modulating, or inhibiting immune cell activity or any cancer or tissue cell type
Search Result Description Here Copy Image URL via instructions below Copy Image URL via instructions below Put in Links to Lab website and USPTO patent: INV-23048 Background: Mitochondria are intracellular organelles that power cells by maintaining cellular homeostasis and contributing to vital cellular functions. They play an...
Published: 9/10/2024   |   Inventor(s): Tania Konry, Judene Thomas, Agustin De Ganzó
Keywords(s):  
Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology
Antibody-based Rolling Circle Amplification for COVID-19 Detection by a Colorimetry
INV-21038 Background Viruses are conventionally detected by RT-PCR. This method requires long analysis time, highly trained professionals, and often shows non-specific characteristics. Antigens and antibodies (Ag/Ab) are commonly used for fluorescence immunoassay. However, the fluorescent signal from the individual fluorescent molecule attached...
Published: 9/10/2024   |   Inventor(s): Ji Won Lim, Tania Konry
Keywords(s): Analytical Chemistry, COVID-19, Detection, Diagnostics
Category(s): -Method, Technology Classifications > 1. Life Science, Diagnostics, Chemistry
Novel bioassay platform for drug and immunotherapy screenings in a personalized format for highly functional cell expansion
INV-19076 Background Immunological screenings for different infections and cancers can yield essential information for developing effect treatments. The efficiency and accuracy of screenings can be improved by choosing efficient matrices and type of assay. Different 3D matrices have been used for immunological screenings. However, due to limited...
Published: 9/10/2024   |   Inventor(s): Giovanni Ugolini, Tania Konry
Keywords(s): Analytical Chemistry, Assays, Detection, Immunological/Autoimmune Disease, Microfluidics
Category(s): -Biomedical Materials, -Chemistry, -Devices, -Equipment, -Cancer
Single-cell Pairing Chip for Personalized Immunotherapeutic Screening
INV-19067 Background Natural Killer cells are a type of white blood cell that physically interact with target cancer cells and determine whether to lyse them. The innate heterogeneity of both cancer and NK cells leads to a variety of interactions between pairs of NK-cancer cells. Therefore, single-cell analysis would help in analyzing these interactions...
Published: 9/10/2024   |   Inventor(s): Yantao Fan, Tania Konry
Keywords(s): Biotech, Cancer
Category(s): -Biology, -Devices, -Cancer, Technology Classifications > 1. Life Science, Diagnostics, Chemistry, Technology Classifications > 1. Life Science > Drug Discovery
A Parallel Droplet Microfluidic Device for Monitoring of Bacteria Culture and Multi-drug Screening
INV-17084 Background To combat antibiotic-resistant bacterial infections there is a need for rapid discovery of new antibiotic drugs. Traditionally antibiotic testing is performed by methods such as an antimicrobial susceptibility test (AST) that requires longer analysis time. New techniques such as MALDI-TOF mass spectroscopy and nucleic acid amplification...
Published: 9/10/2024   |   Inventor(s): Wenjing Kang, Tania Konry
Keywords(s):  
Category(s): -Devices, Technology Classifications > 2. Physical Science > Lab tech/equipment, Antimicrobial, Technology Classifications > 1. Life Science > Drug Discovery
Single Cell Fluorescence In Situ Hybridization In Microfluidic Droplets
INV-16002 Background Nuanced variations at the molecular, cellular and physiological level among individuals require designing personalized treatments, which are tailored to their unique characteristics. Cellular heterogeneity and the need for personalized therapeutic interventions provide a strong rationale to perform analysis at single-cell level....
Published: 9/10/2024   |   Inventor(s): Tania Konry, Saheli Sarkar
Keywords(s):  
Category(s): Technology Classifications > 1. Life Science > Biotechnology
Exosome Detection in Microfluidic Droplets
INV-17081 Background Extracellular vesicles are secreted by cells and contain essential biological components such as proteins, lipids, and genetic materials. Cells use these vesicles to communicate with other cells. These vesicles could be used to introduce therapeutic agents in cells and detect the diseased condition but, detecting cell-secreted...
Published: 9/10/2024   |   Inventor(s): Saheli Sarkar, Tania Konry
Keywords(s):  
Category(s): -Cancer, Diagnostics, Technology Classifications > 1. Life Science > Biotechnology
Live Single-Cell Bioassay in Micro-droplets
INV-17085 Background The outcome of many pathological diseases including cancer is determined by types (functional and phenotypical) of immune cells present in the body. The existence of tremendous heterogeneity in these cells influences the time taken for the immune reaction and an individual’s ability to recover from the illness. Hence, assessing...
Published: 9/10/2024   |   Inventor(s): Tania Konry, Saheli Sarkar, Pooja Sabhachandani
Keywords(s):  
Category(s): -Method, -Cancer, Technology Classifications > 1. Life Science, Diagnostics
Real-Time multiplex Measurement of Antibody-Antigen Binding Constant using Lab-on-a-Chip (LOC) device
INV-14118 Background A major challenge in the detection of soluble molecules, such as biomolecules, drugs, proteins, antigens, and antibodies, is the ability to monitor time‑varying concentrations and reaction association/dissociation constraints in real‑time. This technology comprises a microsphere-based immunoassay fitted to a microfluidic-based...
Published: 9/10/2024   |   Inventor(s): Tania Konry, Noa Cohen, Alexander Golberg
Keywords(s):  
Category(s): -Devices, -Sensors tech, Diagnostics
Functional phenotyping of cells in droplet based platforms
INV-16003 Background Recently, the development of microfluidic, technology-enabled analysis of cell phenomena on the single-cell level has been a growing area of research within the academic realm. Current microfluidic platforms based on micro-well technologies do not provide a robust protocol for cell co-encapsulation in a controllable microenvironment,...
Published: 9/10/2024   |   Inventor(s): Tania Konry, Saheli Sarkar
Keywords(s): Diagnostics, Microfluidics, Singe cell
Category(s): -Microbiology, Technology Classifications > 1. Life Science > Therapeutics
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