Search Results - slava+epstein

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Method and Device for Cultivation and Analysis of Novel Microbial Species with Unknown Growth Requirements
INV-15097 Background: The annual death rate due to antibiotic resistance was expected to reach 10 million by 2050. However, no new class of antibiotics has been introduced as a successful treatment option since 1987. Lack of new antibiotics is due to the fact that we do not have access to many microbial species in their natural environment, or we...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s):  
Category(s): -Microbiology
New Method for Discovery of Bioactive Molecules
INV-20024 Background Microbes are a foundation of the discovery of bioactive molecules because they produce an enormous variety of secondary metabolites, some with desirable activities ranging from antibiotics to anti-inflammatory to anticancer to industrial enzymes. The advent of next-generation sequencing technologies uncovered that microbial genomes...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s): Antimicrobial, Biomolecules, Cancer, Drugs, Microbiology
Category(s): -Method, Antimicrobial, Technology Classifications > 1. Life Science > Gene sequencing, Technology Classifications > 1. Life Science > Drug Discovery
Method and Device for Drug Discovery
INV-1253 Background Historically, natural products and microorganisms have been considered as the major sources of new pharmaceutical compounds. However, in recent years, there has been a dramatic drop in natural-based drug discovery from big pharmaceutical companies. The major challenges are the prevailing paradigm for drug discovery in large pharmaceutical...
Published: 9/10/2024   |   Inventor(s): Slava Epstein
Keywords(s): Analytical Chemistry, Biotech, Drug Discovery & Development, Infectious Disease (including AIDS), Process, Research Tool
Category(s): -Analytical Chemistry, -Health, -Microbiology, Technology Classifications > 2. Physical Science > Lab tech/equipment, Technology Classifications > 1. Life Science > Drug Discovery