Search Results - yuwei+zhao

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Methods for electrogeneration of reactive oxygen species without external oxygen supply
Background Reactive oxygen species (ROS) are defined as a group of reactive molecules and free radicals derive from molecular oxygen, such as superoxide hydroxyl, hydrogen peroxide (H2O2), and ozone. They are widely used in industry and environmental protection, because of their strong oxidizing ability. Especially H2O2 can exist stable in the environment,...
Published: 9/10/2024   |   Inventor(s): Yuwei Zhao, Ljiljana Rajic, Akram Alshawabkeh
Keywords(s):  
Category(s): -Sustainability / Renewable Tech
Hydrogen Sulfide Releasing Agents
Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 8/22/2024   |   Inventor(s): Ming Xian, Hua Wang, Yu Zhao
Keywords(s): Chemistry
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical
Identification and Use of Heterocyclic Alcohol Compounds for the Treatment of SULT1A1-expressing Cancers
This technology includes the identification and use of heterocyclic alcohol compounds, including RITA and N-BIC, for the treatment of SULT1A1-expression cancers. A high-throughput screen (qHTS) was performed using >1,000 caner cell lines identified a compound called YC-1 (also called Lificiguat) that is effective across cancer cell types that express...
Published: 7/25/2024   |   Inventor(s): Min Shen, Ke Kong, Toble Lee, Samarjit Patnaik, Olivia Lee, Jonathan Shrimp, Mindy Davis, Juan Marugan, Wei Zhao, Matthew Hall
Keywords(s): Agents, Alcohol, anti-cancer, Class, compounds, HETEROCYCLIC, SULT1A1-dependent, VCXXXX, WKXXXX, XCXXXX, XEXXXX
Category(s): Application > Research Materials, Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Oncology
DNA Nanocaged Enzymes
Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...
Published: 2/23/2023   |   Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao
Keywords(s): Bioanalysis, Catalysis, Enzymes
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
Biological H2S / COS Donation by Thiocarbamates
­University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...
Published: 5/2/2022   |   Inventor(s): Michael Pluth, Andrea Steiger, Yu Zhao
Keywords(s):  
Category(s): Chemistry, Physical Science, Therapeutics
Compounds for Thiol-Triggered COS and/or H2s Release and Methods of Making and Using the Same
University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in a class...
Published: 5/2/2022   |   Inventor(s): Michael Pluth, Yu Zhao, Matt Cerda
Keywords(s): Science
Category(s): Chemistry, Engineering, Medical Devices, Physical Science, Therapeutics
Gamma-ketothiocarbamate molecules that release COS
­University of Oregon researchers are studying reactive sulfur species (RSS). Detection, Delivery, and Quantification of Biological H2S Hydrogen sulfide (H2S), commonly known for its unpleasant rotten-egg smell, is now accepted as an important enzymatically-produced biomolecule that plays important roles in living systems. Joining CO and NO in...
Published: 5/2/2022   |   Inventor(s): Michael Pluth, Yu Zhao
Keywords(s):  
Category(s): Chemistry, Diagnostics, Engineering, Medical Devices, Physical Science, Research Tools, Therapeutics
2015-182 FLEXIBLE BALLOON-INFLATABLE ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY TO ASSESS ENDOLUMINAL LIPID-RICH LESIONS
Case No. 2015-182SUMMARYUCLA researchers have developed a novel flexible balloon-inflatable electrochemical impedance spectroscopy to facilitate the diagnosis of metabolically active atherosclerotic lesions.BACKGROUNDIdentifying metabolically active atherosclerotic lesions remains an unmet clinical challenge during coronary intervention. Detection of...
Published: 8/9/2024   |   Inventor(s): Fei Yu, Yu-Chong Tai, Yu Zhao, Tzung Hsiai
Keywords(s): Cardiovascular, Medical Devices and Materials, Monitoring And Recording Systems
Category(s): Medical Devices, Medical Devices > Monitoring And Recording Systems, Therapeutics > Cardiovascular
Hybrid Plasmonic Platform for Directing and Controlling Nanostructure Growth
Low-Heat, Bottom-Up Approach Can Produce Metal, Polymer or Bio-Molecule Structures for Catalysis, Biosensors, Electronic Devices and MoreThis surface plasmon mediated chemical solution deposition method uses surface plasmon resonance to deposit nanoparticles in the liquid phase at room temperature to direct and control nanostructure growth. Plasmonic...
Published: 6/27/2021   |   Inventor(s): Wei Wei, Jingjing Qiu
Keywords(s): Catalysts, nanoparticle synthesis, Plasmonic, Thin Films
Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials