Search Results - v+kalyanaraman

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Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth

An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...

Published: 9/12/2025 | Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij

Keywords(s): Driving Lifelong Health

Category(s): Life Science, Medical Devices, Imaging, Acoustics, Women's Health

Reliable Liquid Metal Composites for Soft Robotics, Electronics, and Thermal Management

This invention introduces oxide-flake-stabilized liquid metal powders that suppress supercooling, enabling reliable phase transitions for tunable stiffness, thermal management, and adaptive devices. Background: Liquid metal (LM)-based composites are promising for tunable stiffness, shape memory, and thermal management applications in robotics, electronics,...

Published: 9/9/2025 | Inventor(s): Pu Zhang, Jiexian Ma

Keywords(s): CleanTech

Category(s): Campus > Binghamton University, Technology Classifications > Engineering

Unlocking the Power of Device-Free Cold Plasma for Tumor Sensitization

Current cancer treatments like chemotherapy and radiation often struggle to target cancer cells without harming healthy tissue. Many tumors—especially aggressive or drug-resistant types—remain difficult to treat due to limited drug penetration, poor selectivity, and systemic toxicity. There is a pressing need for a method that can sensitize...

Published: 9/12/2025 | Inventor(s): Michael Keidar, Dayun Yan

Keywords(s):

Category(s): Technology Classifications > Research Tools > Buffers and Media, Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Small Molecules

Ampule-Based Synthesis of Sulfur-Porous Carbon Composites for Lithium-Sulfur Batteries

Background Lithium/sulfur (Li/S) batteries are garnering significant attention as a promising solution for next-generation electrochemical energy storage. Their potential to revolutionize the battery industry stems from several key advantages that address the limitations of current lithium-ion (Li-ion) technology. These advantages include an exceptionally...

Published: 8/21/2025 | Inventor(s): Yoon Hwa, David Wright, Yuhui An

Keywords(s): Chemicals, Energy storage, Engineering, Materials, Nanomaterials, Synthesis

Category(s): Energy & Power, Physical Science, Advanced Materials/Nanotechnology, Semiconductors, Materials & Processes

C8166-45 Cells

Summary: The National Cancer Institute (NCI) seeks licensees for a human T-cell line, C8166-45, transformed by HTLV-1. C8166-45, also known as C63/CRII-2, contains three transcriptionally active proviruses useful for testing biological activities involved in T-cell immortalization and growth. Description of Technology: ...

Published: 8/21/2025 | Inventor(s): Genoveffa Franchini, Syed Salahuddin, Flossie Wong-Staal, Robert Gallo, Phillip Markham, V Kalyanaraman

Keywords(s):

Category(s): Application > Research Materials, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology, Collaboration Sought > Licensing

A conserved viral peptide for use in cancer immunotherapy

Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for viral peptide (CE1)-based therapeutics for HCC prevention and treatment. Description of Technology: Hepatocellular carcinoma (HCC) is a common and aggressive primary liver cancer. It develops mainly from at-risk individuals with underlying chronic...

Published: 8/21/2025 | Inventor(s): Xin Wei Wang, Lichun Ma, Man Hsin Hung

Keywords(s):

Category(s): TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing, Collaboration Sought > Collaboration

High-Potency Biased β2-adrenergic Receptor Agonist for Treating Respiratory Diseases

Advantages Ultra-potent β2-adrenergic receptor agonist that stimulates cAMP production with sub-nanomolar potency (EC50 = 0.25nM) Biased signaling profile selectively activates Gαs-mediated cAMP signaling while avoiding β-arrestin2 recruitment, reducing receptor desensitization characteristic of traditional treatments such as albuterol Maintains...

Published: 5/27/2025 | Inventor(s): Stephen Liggett, Donghwa Kim, Yu Chen, Jesper Madsen, Steven An

Keywords(s): Pharmaceuticals, Respiratory Diseases Treatment

Category(s): Technology Classifications > Medical > Respiratory, Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals

A novel approach to the treatment of EGFR mutant non-small cell lung cancer (NSCLC)

Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for ~85% of all lung cancer cases. NSCLC is slow growing and often diagnosed at later stages when it has already spread, making treatment difficult. Resistance to therapy is a major challenge in effectively treating patients with NSCLC. 10-30% of...

Published: 8/14/2025 | Inventor(s): Jack Elias, Suchitra Kamle, Chun Geun Lee, Bing Ma

Keywords(s):

Category(s): Oncology

Functional Hierarchical Porous Organic Polymers for Water Purification

Advantages: High absorption capacity Fast and controllable kinetics Facile regeneration and recyclability Stable under a wide range of conditions High density of chelating sites Summary: Water and energy purification are important factors in minimizing the harsh impact of technology on the environment. Coal-powered fuel stations and waste...

Published: 3/4/2025 | Inventor(s): Shengqian Ma, Qi Sun, Briana Aguila

Keywords(s):

Category(s): Technology Classifications > Energy & Environment

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 5/30/2025 | Inventor(s): Yong Zeng, He Yan

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

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