Search Results - v+kalyanaraman

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Curative Locoregional Therapy Using Ablation or Catheter-Based Embolization of Targeted Hepatocellular Carcinoma by Delivering Supercharged NK Cells and CAR-NK or CAR-T Cells (UCLA Case No. 2023-115)
UCLA researchers in the School of Dentistry and Interventional Radiology have developed a groundbreaking curative treatment for hepatocellular carcinoma that combines locoregional therapy, such as ablation or catheter-based embolization, with targeted delivery of supercharged NK cells and CAR-NK or CAR-T cells, offering a highly effective approach that...
Published: 10/23/2025   |   Inventor(s): Anahid Jewett, Steven Raman, Jason Chiang
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Oncology > Oncology Immunotherapy
NPEPPS Enhancers for Treating Tau-Induced Neurodegeneration (UCLA Case No. 2018-161)
UCLA researchers from the Department of Neurology have developed first-in-class small-molecule activators of NPEPPS that effectively lower pathological tau, offering a novel disease-modifying strategy for Alzheimer’s and other neurodegenerative disorders. BACKGROUND: Neurodegenerative dementias such as Alzheimer’s Disease (AD) and progressive...
Published: 10/22/2025   |   Inventor(s): Daniel Geschwind, Robert Damoiseaux, Liting Deng, Michael Jung, Jennifer Murphy, Gaoyuan Ma
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology, Diagnostic Markers > Targets And Assays
Tumor-pH–Triggered Doxorubicin Prodrug with On-Demand Shelf-Stable Precursor
This invention introduces a small-molecule doxorubicin prodrug that remains inert in blood and rapidly activates in the mildly acidic tumor microenvironment. Featuring a shelf-stable maleimide pre-prodrug that converts on demand to the ultra-acid-labile DMA form, it enables targeted chemotherapy with improved selectivity, scalable synthesis, and reduced...
Published: 10/10/2025   |   Inventor(s): Ming An, Lan Yao, Vladyslav Nazarenko
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Antisolvent-mediated Air Quench for High Efficiency Air-processed Carbon-Based Planar Perovskite Solar Cells
Invention Description Perovskite solar cells (PSCs) have been rigorously researched and pursued as a potential low-cost, next-generation thin-film photovoltaic technology. PSCs have now achieved certified power conversion efficiencies (PCEs) exceeding 26%, which paves the way to commercial upscale manufacturing. However, the commercialization of PSCs...
Published: 10/7/2025   |   Inventor(s): Feng Yan, Jacob Wall
Keywords(s): Materials and Electronics, Solar cells
Category(s): Advanced Materials/Nanotechnology, Alternative Energy, Energy & Power, Manufacturing/Construction/Mechanical, Physical Science, Semiconductors, Materials & Processes
Printable and Lightweight Perovskite Solar Films and Devices
Invention Description Perovskite solar cells (PSCs) are a next generation thin film solar cell technology with advantages including high efficiency, low-cost fabrication approaches and flexile applications. However, current PSCs still require noble metal electrodes as well as expensive transparent electrodes which increase overall cost and may have...
Published: 9/25/2025   |   Inventor(s): Feng Yan
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Physical Science, Alternative Energy, Energy & Power
Rapid 3D Printing of Aerogels with Bioinspired Surface Structures for Solar Steam Generation
Invention Description Freshwater scarcity is a critical global challenge. Desalination and water purification, particularly through solar steam generation, offer promising solutions by converting seawater and polluted water into freshwater using solar energy. Aerogels doped with reduced graphene oxide (rGO) enhance this process by improving water transport...
Published: 9/24/2025   |   Inventor(s): Xiangfan Chen, Luyang Liu, Chao Ma
Keywords(s): Additive Manufacturing, Advanced manufacturing, Bio Inspired Design, Materials, water processing, Water Purification
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Environmental, Environmental Remediation/Wastewater Treatment, Physical Science
Ultrafast Doping in Polycrystalline Chalcogenides
Background Cadmium telluride (CdTe) photovoltaic technology is considered one of the most successful commercial thin film solar cell technologies, boasting a power conversion efficiency of approximately 23%. Despite this achievement, the current power conversion efficiency for CdTe modules is still far from the theoretical power conversion efficiency...
Published: 9/15/2025   |   Inventor(s): Feng Yan
Keywords(s): PS-Advanced Materials and Nanotechnology, PS-Energy and Power, PS-Environmental, Solar cells, Solar Energy, Thin Films
Category(s): Advanced Materials/Nanotechnology, Alternative Energy, Energy & Power, Environmental, Physical Science
All-Inorganic Perovskites/Chalcogenides Multijunction Solar Cells
Background All-inorganic perovskite solar cells (AI-PSCs) have emerged as a promising technology in the field of photovoltaics, offering significant advancements in efficiency and stability. Perovskite materials as solar energy absorbers are traditionally developed with hybrid organic-inorganic perovskites. These types of hybrid materials demonstrate...
Published: 9/15/2025   |   Inventor(s): Feng Yan
Keywords(s): PS-Advanced Materials and Nanotechnology, PS-Energy and Power, PS-Environmental, Solar cells, Solar Energy, Thin Films
Category(s): Advanced Materials/Nanotechnology, Alternative Energy, Energy & Power, Environmental, Physical Science
Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 10/1/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Technology Category > Women's Health, Technology Category > Medical Devices, Technology Category > Life Science, Technology Category > Imaging, Technology Category > Acoustics
Reliable Liquid Metal Composites for Soft Robotics, Electronics, and Thermal Management
This invention introduces oxide-flake-stabilized liquid metal powders that suppress supercooling, enabling reliable phase transitions for tunable stiffness, thermal management, and adaptive devices. Background: Liquid metal (LM)-based composites are promising for tunable stiffness, shape memory, and thermal management applications in robotics, electronics,...
Published: 9/24/2025   |   Inventor(s): Pu Zhang, Jiexian Ma
Keywords(s): CleanTech
Category(s): Campus > Binghamton University, Technology Classifications > Engineering
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