Search Results - malla+reddy+gannarapu

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nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Hongmin Li, Rui Xiong, Subodh Samrat, Malla Reddy Gannarapu, Ran Zhang, Ke Chen, Mengjiao Ma, Omar Alejandro Lozano Ramos, Divakar Indukuri, Renu Bhardwaj
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
Calcium/Calmodulin-Regulated Plant Immunity
Unmet Need: Understanding the mechanism of regulation of salicylic acid by Ca2+ signaling Intracellular calcium transients during plant-pathogen interactions are necessary early events leading to local and systemic acquired resistance. Salicylic acid, a critical messenger, is also required for both these responses, but whether and how salicylic acid...
Published: 4/8/2026   |   Updated: 2/22/2018   |   Inventor(s): B Poovaiah, A Reddy, Gul Ali, Tianbao Yang, Kayla Simons, Jingguo Hou, Liqun Du
Keywords(s): Agriculture and Plant Sciences, Biotechnology
Category(s): Technologies > Food & Nutrition > Agriculture and Plant Sciences, Technologies > Health & Well-being > Biotechnology