Search Results - xiaodong+yan

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Stationary Multi-source AI-powered Real-time Tomography (SMART) for Dynamic Cardiac Imaging
RPI ID: 2022-011-201 Innovation Summary: The SMART system uses 29 fixed source-detector pairs arranged on a circular track to perform real-time tomography without mechanical rotation. AI algorithms reconstruct high-resolution 3D images from simultaneous multi-angle data. This architecture improves temporal resolution and reduces wear compared to rotating...
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Weiwen Wu, Yan Xi, Ge Wang
Keywords(s): cardiac Imaging, computed tomography (CT), deep learning, image reconstruction, Multi-Source, preclinical imaging, real-time
Category(s): Computational Science and Engineering
Topological Acoustic Synapse for High-Dimensional Neuromorphic Computing
The Topological Acoustic Synapse is a neuromorphic hardware device that uses acoustic waves to perform high-dimensional neuromorphic computing. The device encodes information in a multivariate state space and uses nonlinear acoustic wave interactions to reproduce synapse-like behavior for computation. By shifting key functions from purely electronic...
Published: 2/3/2026   |   Updated: 2/3/2026   |   Inventor(s): Xiaodong Yan, Jinli Chen, Akinsanmi Ige, Pierre Deymier, Keith Runge
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Electronics
Multi-parametric Acoustic, Optical and Mechanical Imaging of Cervical Tissue Insufficiencies to Predict Preterm Birth
An enhanced image-guidance system that integrates ultrasound and photoacoustic into existing ablation systems to provide an enhanced image-guidance system for identification of cervical tissue changes during pregnancy and postpartum. Technology Summary Preterm delivery is a main cause of perinatal morbidity and mortality worldwide, which is associated...
Published: 10/1/2025   |   Updated: 9/10/2025   |   Inventor(s): Mohammad Mehrmohammadi, Sonia Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij
Keywords(s): Driving Lifelong Health
Category(s): Technology Category > Women's Health, Technology Category > Medical Devices, Technology Category > Life Science, Technology Category > Imaging, Technology Category > Acoustics
Human and Improved Murine Monoclonal Antibodies Against CD22
Abstract: CD22 is a common cell surface glycoprotein expressed in B-cells and present in B-cell lymphomas; e.g., hairy cell leukemia (HCL), non-Hodgkins lymphoma (NHL), chronic lymphoblastic leukemia (CLL), and other cancers. It is therefore a target for cancer immunotherapy. Conjugation of anti-CD22 monoclonal antibodies with toxins or drugs has shown...
Published: 4/22/2025   |   Updated: 8/2/2023   |   Inventor(s): Dimiter Dimitrov, Xiaodong Xiao, Ira Pastan
Keywords(s): antibodies, ANTIGEN, B-CELL, B-Cell Lymphoma, Bcl, CANCER, CD22, Chronic Lymphoblastic Leukemia, CLL, Dimitrov, Hairy cell leukemia, HCL, Human, monoclonal, NHL, non-Hodgkins lymphoma, Oncology
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics