Search Results - transplant

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Method for Combined Conditioning and Chemoselection in a Single Cycle (UCLA Case No. 2011-478)
SUMMARY: Researchers at UCLA have developed a highly-efficient technique to engraft and select hematopoietic stem cells directly inside a patient. The invention will improve the fidelity of stem cell transplantations and reduce toxic side effects on patients. BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a mainstay of treatment for...
Published: 2/16/2024   |   Inventor(s): Gay Crooks, Robert Schiestl, Katrin Hacke, Akos Szakmary
Keywords(s): blood cancers, Cancer stem cells, Hematopoietic stem cell transplantation, hematopoietic stem cells, lymphatic cancer, stem cell transplantations, Transplant
Category(s): Therapeutics > Stem Cells And Regenerative Medicine, Therapeutics > Transplant
Development of Immune System Tolerance for the Treatment of Autoimmune Disease
The present invention provides a therapeutic method for the treatment of autoimmune or autoinflammatory diseases by first breaking down the dysregulated immune system and then reprogramming the immune system to restore tolerance to the patient's self-antigens by induction of antigen specific regulatory T cells. The inventors have shown that only with...
Published: 10/28/2024   |   Inventor(s): Wanjun Chen
Keywords(s): Alloantigen-specific, Apototic, CELL-MEDIATED, Cells, IB3XXX, IBXXXX, INDUCTION, IXXXXX, Patent Category - Biotechnology, Prevention, Regulatory, REJECTION, T, TRANSPLANT
Category(s): TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics, Application > Therapeutics
Self-oxygen generating biomaterials for large tissue engineering
Organ transplantation continues to increase, with 34,770 transplants performed in the US in 2017. Currently, organ transplantation is limited by donor dependence, high costs, and, long-term use of immunosuppressive medications which, in turn, correlates with significant morbidity and mortality. To overcome these limitations, tissue engineering and transplantation...
Published: 3/5/2024   |   Inventor(s): Iman Noshadi
Keywords(s): Biomaterials, Electrolyte, Energy Storage, Hydrogels, Oxygenation, Regenerative Medicine, Scaffold, Stem Cells, Tissue Engineering , Transplant
Category(s): Human Health Care > Biomaterials