Search Results - transplant+rejection

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2020-421 EXTRACELLULAR VESICLES DERIVED FROM INDUCED PLURIPOTENT STEM CELLS FOR IMMUNOMODULATION
UCLA researchers in the Department of Bioengineering have developed a method to boost extracellular vesicles' (EVs) production and potency, potentially allowing large-scale clinical-grade EV manufacture for immunomodulatory therapeutics. BACKGROUNDExtracellular vesicles (EVs) are one of the most important mediators of cell-to-cell communication. EVs...
Published: 7/19/2023   |   Inventor(s): Jana Zarubova, Mohammad Hasani-Sadrabadi, Song Li
Keywords(s): Immunology, Therapeutics & Vaccines, Transplant Rejection
Category(s): Life Science Research Tools > Research Methods, Therapeutics > Agtech And Animal Health, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Stem Cells And Regenerative Medicine > Ips Stem Cells
Antileukinates in the prevention of transplant rejection
Alpha-chemokines play important roles in both inflammation and tumor development. They bind to specific surface receptors to induce leukocyte migration and activation, angiogenesis, and to stimulate tumor growth. Dr. Miller developed a peptide inhibitor of the α-chemokine receptors, CXCR1 and CXCR2, and went on to show that this inhibitor (dubbed...
Published: 4/26/2016   |   Inventor(s): Edmund Miller, Shin Hirayama, Takeshi Shiraishi
Keywords(s): Transplant rejection
Category(s): Inflammation and Autoimmunity