Search Results - macular+degeneration

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Angiogenesis-Based Cancer Therapeutic
Abstract: Vascular Endothelial Growth Factor-A (VEGF-A) is an angiogenic agent that drives blood vessel formation in solid tumors and other diseases, such as macular degeneration and diabetic retinopathy. Several therapies that target the ability of VEGF to stimulate angiogenesis have been approved. These therapies regulate VEGF-A activity by binding...
Published: 4/8/2024   |   Inventor(s): Donald Bottaro, Fabiola Cecchi
Keywords(s): ANGIOGENESIS, CHEMOTHERAPY, Diabetic Retinopathy, FLT-1, Heparin sulfate proteoglycan, Hepatocyte growth factor (HGF), KDR/FLK-1, Macular degeneration, VEGF-A
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
AI Models for Ocular Diseases Using Optical Coherence Tomography (Case No. 2022-113)
Summary: UCLA researchers in the Department of Computational Medicine have developed a computer program capable of automatically and accurately diagnosing optical diseases using OCT. Background: Optical diseases, such as age-related macular degeneration, are serious issues that, if left untreated, can result in partial and even complete blindness....
Published: 10/31/2024   |   Inventor(s): Jeffrey Chiang, Srinivas Sadda, Eran Halperin
Keywords(s): Algorithm Optical Coherence Tomography, Artificial Intelligence, Eye Surgery, Intraocular Lens , Lens (Optics), Macular Degeneration, Optical Coherence , Optical Microscope, Optical Tomography
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices > Medical Imaging
2020-439 4F FOR AMD
Researchers at UCLA’s David Geffen School of Medicine, in collaboration with researchers from the University of Lubeck, Germany, have developed an anti-inflammatory, antiatherogenic peptide which ameliorates symptoms and progression of age-related macular degeneration (AMD) and could work to reduce the severity of other eye diseases presenting...
Published: 7/19/2023   |   Inventor(s): Alan Fogelman, Mohamad Navab, Gattadahalli Anantharamaiah, Martin Rudolf
Keywords(s): Macular Degeneration, Peptide
Category(s): Platforms > Drug Delivery > Peptide Base
AAV Vector that Promotes Antioxidant Production for Treatment of Age-Related Macular Degeneration
Gene Therapy Requires Just One Intraocular Injection to Treat Eye Ailment Caused by Oxidative StressThis AAV gene therapy approach provides a one-time treatment to oxidative stress. Sustained oxidative stress can lead to a variety of pathophysiological diseases including age-related macular degeneration, diabetic retinopathy, and amyotrophic lateral...
Published: 12/22/2022   |   Inventor(s): Qiuhong Li, Christhian Ildefonso, Alfred Lewin
Keywords(s): Age Related Macular Degeneration, Alzheimer's Disease, Diabetic Retinopathy, Gene Therapy, Macular Degeneration, Retinal Degeneration, uveitis
Category(s): Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Others