Search Results - macular+degeneration

5 Results Sort By:
Intrastromal Lamellar Keratoprosthesis (Artificial Cornea) (Case No. 2025-177)
Summary: UCLA researchers in the Department of Ophthalmology have developed an intrastromal artificial cornea implant designed to enhance biointegration and effectively restore vision. Background: Corneal opacities are among the top five causes of blindness worldwide. For patients who are not candidates for conventional corneal transplantation, keratoprosthesis...
Published: 7/25/2025   |   Inventor(s): Seyed Reza Ghaffari Dehkharghani, Anthony Aldave
Keywords(s): Biologic Medical Product, Biomedical Engineering, biomedical implantation, biomedical sensors, diseases of the eye, eye disease, eye motion, eye movement disorders, Eye Surgery, eye tracking, Glaucoma, macular corneal dystrophy, Macular Degeneration, Medical Device, Medical Imaging Eyepiece, on-eyelid sensor, Ophthalmic antibiotics, Ophthalmology, Other Polymers, Polymers, Prosthetics, Transplant, Transplant Rejection, transplant surgery
Category(s): Medical Devices, Medical Devices > Surgical Tools, Therapeutics > Ophthalmology
Intravitreal Injection Device (Case No. 2024-136)
Summary: Researchers in the Department of Ophthalmology at UCLA have developed an intravitreal injection device for safer and more precise injections. Background: Intravitreal injections are vital for treating sight-threatening retinal conditions like age-related macular degeneration and diabetic macular edema. These conditions rely heavily on accurate...
Published: 2/28/2025   |   Inventor(s): Taras Gout, Robert Goldberg
Keywords(s): diseases of the eye, Eye Surgery, Macular Degeneration, Ophthalmic antibiotics, Ophthalmology
Category(s): Medical Devices > Surgical Tools, Therapeutics > Ophthalmology, Medical Devices > Hospital Systems
Angiogenesis-Based Cancer Therapeutic
Abstract: Vascular Endothelial Growth Factor-A (VEGF-A) is an angiogenic agent that drives blood vessel formation in solid tumors and other diseases, such as macular degeneration and diabetic retinopathy. Several therapies that target the ability of VEGF to stimulate angiogenesis have been approved. These therapies regulate VEGF-A activity by binding...
Published: 4/22/2025   |   Inventor(s): Donald Bottaro, Fabiola Cecchi
Keywords(s): ANGIOGENESIS, CHEMOTHERAPY, Diabetic Retinopathy, FLT-1, Heparin sulfate proteoglycan, Hepatocyte growth factor (HGF), KDR/FLK-1, Macular degeneration, VEGF-A
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
AI Models for Ocular Diseases Using Optical Coherence Tomography (Case No. 2022-113)
Summary: UCLA researchers in the Department of Computational Medicine have developed a computer program capable of automatically and accurately diagnosing optical diseases using OCT. Background: Optical diseases, such as age-related macular degeneration, are serious issues that, if left untreated, can result in partial and even complete blindness....
Published: 4/30/2025   |   Inventor(s): Jeffrey Chiang, Srinivas Sadda, Eran Halperin
Keywords(s): Algorithm Optical Coherence Tomography, Artificial Intelligence, Eye Surgery, Intraocular Lens , Lens (Optics), Macular Degeneration, Optical Coherence , Optical Microscope, Optical Tomography
Category(s): Software & Algorithms, Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices > Medical Imaging
AAV Vector that Promotes Antioxidant Production for Treatment of Age-Related Macular Degeneration
Gene Therapy Requires Just One Intraocular Injection to Treat Eye Ailment Caused by Oxidative StressThis AAV gene therapy approach provides a one-time treatment to oxidative stress. Sustained oxidative stress can lead to a variety of pathophysiological diseases including age-related macular degeneration, diabetic retinopathy, and amyotrophic lateral...
Published: 12/22/2022   |   Inventor(s): Qiuhong Li, Christhian Ildefonso, Alfred Lewin
Keywords(s): Age Related Macular Degeneration, Alzheimer's Disease, Diabetic Retinopathy, Gene Therapy, Macular Degeneration, Retinal Degeneration, uveitis
Category(s): Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Human Health Care > Others