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Search Results - sankaran+thayumanavan
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Noncationic Nucleic Acid-Polymer Complexes for Nucleic Acid Delivery
PRODUCT OPPORTUNITIESNoncationic nucleic acid-polymer complexes for nucleic acid deliveryNucleic acid-polymer complexation kits for nucleic acid encapsulation and intracellular deliveryNovel polymers for nucleic acid delivery with substantially reduced cytotoxicityPRODUCT OPPORTUNITIESCOMPETITIVE ADVANTAGESAn efficient nucleic acid delivery system with...
Published: 10/26/2023
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Inventor(s):
Sankaran Thayumanavan
Keywords(s):
Category(s):
Biotechnology
,
Healthcare
,
Nanotechnology
,
Life Sciences
,
Therapeutics & prevention
Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics
PRODUCT OPPORTUNITIES Cell-membrane-coated, cargo-encapsulated polymer nanoparticles as target-specific prodrugs PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Enhanced cellular uptake and endosomal escape, resulting in more efficient delivery of therapeutics Enhanced selectivity of intracellular delivery of therapeutics TECHNOLOGY...
Published: 8/10/2023
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Inventor(s):
Sankaran Thayumanavan
Keywords(s):
Category(s):
Healthcare
,
Life Sciences
,
Biotechnology
,
Nanotechnology
,
Therapeutics & prevention
,
Research tools
Polymeric Nanogles for the Encapsulation, Delivery and pH-Triggered Release of Proteins
PRODUCT OPPORTUNITIESNanogel encapsulated protein therapeutics for the treatment of lysosomal storage diseasesNanogel encapsulated diagnostic, imaging or sensing agentsPRODUCT OPPORTUNITIESCOMPETITIVE ADVANTAGESStably encapsulated proteins that are not prone to proteolytic degradation when being delivered to the target siteControlled release of the...
Published: 8/10/2023
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Inventor(s):
Sankaran Thayumanavan
,
Mijanur Molla
,
Scott Garman
Keywords(s):
Category(s):
Biotechnology
,
Diagnostic technology
,
Healthcare
,
Life Sciences
,
Nanotechnology
,
Research tools
Novel Protein-Polymer Nanoassemblies for the Intracellular Delivery and Stimuli-responsive Traceless Release of Proteins
PRODUCT OPPORTUNITIES Novel protein-polymer conjugates as prodrugs Therapeutic protein-polymer conjugation kits PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Reversible and ultrafast click reaction between surface modified protein and synthetic polymer, enabling efficient protein encapsulation and triggered intracellular release Versatile...
Published: 10/3/2023
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Inventor(s):
Sankaran Thayumanavan
,
Bin Liu
Keywords(s):
Category(s):
Biotechnology
,
Healthcare
,
Life Sciences
,
Nanotechnology
,
Research tools
Novel Chemical Reagents for Antibody-Drug Conjugation, Protein Delivery, and Traceless Release
PRODUCT OPPORTUNITIESNovel chemical reagents for antibody-drug conjugation, protein delivery, and traceless releaseAntibody-drug conjugates with reversible linkerNovel chemical reagent-functionalized polymeric delivery vehicles for protein delivery and traceless releasePRODUCT OPPORTUNITIESCOMPETITIVE ADVANTAGESReversible bonding reaction with small...
Published: 8/10/2023
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Inventor(s):
Sankaran Thayumanavan
,
Jiaming Zhuang
Keywords(s):
Category(s):
Biotechnology
,
Life Sciences
,
Research tools
New Protein Labeling Reagents for Improved Protein Structural Analysis by Mass Spectrometry
PRODUCT OPPORTUNITIESNew protein labeling reagents for improved protein structural analysis by mass spectrometryPRODUCT OPPORTUNITIESCOMPETITIVE ADVANTAGESCapable of reacting with a wider range of surface-exposed amino acid residues in proteins, leading to greater structural coverage as compared with commonly used protein labeling reagents for mass...
Published: 12/23/2019
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Inventor(s):
Richard Vachet
,
Sankaran Thayumanavan
,
Bo Zhao
,
Jiaming Zhuang
Keywords(s):
Category(s):
Chemicals
,
Life Sciences
,
Research tools
A Novel Non-cationic Lipid-polymer-based Nanossembly for the Complexation and Intracellular Delivery of Nucleic Acids
PRODUCT OPPORTUNITIES Non-cationic lipid-polymer-nucleic acid nanoassembly for efficient delivery of nucleic-acid-based therapeutics such as siRNAs PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Non-cationic nucleic acid delivery system that mitigates carrier associated cytotoxicity Symbiotic, self-assembled delivery system with...
Published: 10/3/2023
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Inventor(s):
Sankaran Thayumanavan
,
Kingshuk Dutta
Keywords(s):
Category(s):
Biotechnology
,
Healthcare
,
Life Sciences
,
Nanotechnology
,
Therapeutics & prevention
Novel Polymeric Nanogels for Controlled Intracellular Protein Delivery and Traceless Release
PRODUCT OPPORTUNITIES Nanogel encapsulated protein prodrugs or therapeutics Nanogel encapsulated diagnostic agents Protein encapsulation reagents and kits for intracellular delivery and traceless release PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Broadly applicable protein encapsulation and delivery technology (capable of encapsulating...
Published: 10/3/2023
|
Inventor(s):
Sankaran Thayumanavan
,
Jiaming Zhuang
Keywords(s):
Category(s):
Life Sciences
,
Biotechnology
,
Healthcare
,
Research tools
,
Therapeutics & prevention
,
Nanotechnology
,
Diagnostic technology
Hyaluronic Acid Based Nanogel or Microgel Compositions for Targeted Delivery of Small Molecule Therapeutics
PRODUCT OPPORTUNITIESCrosslinked hyaluronic acid - small molecule nano- or micro-assemblies as therapeutics for immune-mediated inflammatory diseasesCrosslinked hyaluronic acid - small molecule nano- or micro-assemblies as therapeutics for canerCrosslinked hyaluronic acid - small molecule nano- or micro-assemblies as diagnostic agentsCrosslinked hyaluronic...
Published: 8/10/2023
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Inventor(s):
Sankaran Thayumanavan
,
Lisa Minter
Keywords(s):
Category(s):
Biotechnology
,
Diagnostic technology
,
Healthcare
,
Life Sciences
,
Nanotechnology
,
Research tools
,
Therapeutics & prevention
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 4/19/2023
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Inventor(s):
Jianming Liang
,
Yu An
,
Wei Liu
Keywords(s):
Category(s):
Computing & Information Technology
,
Life Science (All LS Techs)
,
Medical Imaging
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