Search Results - therapeutics+%26+prevention

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Demineralized Bone Paper and Applications Thereof
PRODUCT OPPORTUNITIES • Three-dimensional, living bone tissue grafts produced from stacked demineralized bone paper (DBP) for clinical applications • DBP-based high-throughput and high-content assay systems for bone disease drug discovery • Other DBP-containing products such as microfluidic bone marrow chips PRODUCT...
Published: 10/1/2025   |   Inventor(s): Jungwoo Lee, Jae-Hyuck Shim, Ryan Carpenter, Yongkuk Park, Jun-Goo Kwak
Keywords(s):  
Category(s): Biotechnology, Devices, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease
PRODUCT OPPORTUNITIES • Cell-based therapy for the prevention of graft-versus-host disease ADVANTAGES • Simple, well-defined generation of personalized, cell-based therapy for the prevention of graft-versus-host disease • Generation of super regulatory T cells with greatly improved suppressive capacity. TECHNOLOGY...
Published: 9/25/2025   |   Inventor(s): Lisa Minter, Gregory Tew, Emrah Ozay
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
Let-7 promotes superior anti-tumor activity of CD8 T cells and memory formation
­ ­PRODUCT OPPORTUNITIES Improve T-cell therapies PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Improve cancer immunotherapies that are based on adoptive T cell transfer/ improves T-cell therapies TECHNOLOGY DESCRIPTION This invention demonstrates that let-7 miRNA regulates T cell responses...
Published: 4/4/2025   |   Inventor(s): Leonid Pobezinsky, Elena Pobezinskaya
Keywords(s):  
Category(s): Biotechnology, Life Sciences, Therapeutics & prevention, Research tools
Localization of Payload Delivery Systems to Tumor Sites via Beacon Cell Targeting
­PRODUCT OPPORTUNITIES Safe and efficacious delivery of payload to a tumor PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Provides possibility to deliver potentially toxic therapy/molecule to bacteria-associated tumors with significantly reduced off-target accumulation while increasing tumor localization, efficacy,...
Published: 3/1/2024   |   Inventor(s): Neil Forbes, Nele Van Dessel, John Klier, Shane Taylor, Vishnu Raman
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Therapeutics & prevention
Noncationic Nucleic Acid-Polymer Complexes for Nucleic Acid Delivery
PRODUCT OPPORTUNITIES Noncationic nucleic acid-polymer complexes for nucleic acid delivery Nucleic acid-polymer complexation kits for nucleic acid encapsulation and intracellular delivery Novel polymers for nucleic acid delivery with substantially reduced cytotoxicity PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES An efficient nucleic...
Published: 11/29/2024   |   Inventor(s): Sankaran Thayumanavan
Keywords(s):  
Category(s): Biotechnology, Healthcare, Nanotechnology, Life Sciences, Therapeutics & prevention
Polymeric Nanoparticle-Based Antibiofilm Therapy
PRODUCT OPPORTUNITIES • Antimicrobial ointment for topical treatments • Antimicrobial injectable for in vivo treatments • Antibiofilm therapy ADVANTAGES • Non-antibiotic based • High efficacy against both planktonic bacteria and more drug-resistant bacterial biofilms •...
Published: 6/7/2024   |   Inventor(s): Vincent Rotello, Ryan Landis, Akash Gupta
Keywords(s):  
Category(s): Healthcare, Life Sciences, Biotechnology, Therapeutics & prevention
Nanoparticle-Stabilized Microcapsules for Effective Treatment of Bacterial Biofilms
PRODUCT OPPORTUNITIES• Antimicrobial ointments and creams for treatments of infected wounds• Antimicrobial toothpaste, mouthwash and dental floss• Disinfectants for biomedical surfacesADVANTAGES• Stable and biocompatible microcapsules • Highly potent in biofilm inhibition and eradication •...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Bradley Duncan, Xiaoning A/k/a Sharlene Li
Keywords(s):  
Category(s): Healthcare, Life Sciences, Nanotechnology, Therapeutics & prevention
Polymeric Nanocapsules for the Treatment of Biofilms
PRODUCT OPPORTUNITIES• Antimicrobial injectables for in vivo treatments of pathogenic biofilms• Antimicrobial ointments and creams for topical treatments of pathogenic biofilms• Antimicrobial toothpaste, mouthwash and dental flossADVANTAGES• Stable and potent antimicrobial polymeric nanocapsules containing...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Ryan Landis, Akash Gupta, Yiwei Lee
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Nanotechnology, Therapeutics & prevention
Efficient Cytosolic Delivery of siRNA Using Nanoparticle-Stabilized Nanocapsules
PRODUCT OPPORTUNITIES• Novel delivery vehicle for the development and delivery of RNAi-based therapeutics• Advanced tool for life science, drug discovery or biomedical research• Efficient intracellular nucleic acid delivery systemADVANTAGES• New mechanism of siRNA delivery that allows for efficient and rapid...
Published: 8/10/2023   |   Inventor(s): Vincent Rotello, Ying Jiang, Rui Tang
Keywords(s):  
Category(s): Biotechnology, Life Sciences, Healthcare, Research tools, Therapeutics & prevention
Bacterial Polysaccharides for Inflammatory Disease
Microbial exopolysaccharides for prevention and treatment of inflammatory diseasePRODUCT OPPORTUNITYADVANTAGES advantages content goes hereTECHNOLOGY DESCRIPTIONInflammation is a healthy biological response which serves to remove harmful irritants and promote healing. However, abnormal inflammation may lead to pain, suffering, and disease, including...
Published: 7/17/2023   |   Inventor(s): Barbara Osborne, Furkan Ayaz, Katherine Knight, Sara Jones
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Therapeutics & prevention
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