Search Results - therapeutics+%26+prevention

23 Results Sort By:
Let-7 promotes superior anti-tumor activity of CD8 T cells and memory formation
­ ­PRODUCT OPPORTUNITIES Improve T-cell therapies PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Improve cancer immunotherapies that are based on adoptive T cell transfer/ improves T-cell therapies TECHNOLOGY DESCRIPTION This invention demonstrates that let-7 miRNA regulates T cell responses...
Published: 11/29/2024   |   Inventor(s): Leonid Pobezinsky, Elena Pobezinskaya
Keywords(s):  
Category(s): Biotechnology, Life Sciences, Therapeutics & prevention, Research tools
Localization of Payload Delivery Systems to Tumor Sites via Beacon Cell Targeting
­PRODUCT OPPORTUNITIES Safe and efficacious delivery of payload to a tumor PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Provides possibility to deliver potentially toxic therapy/molecule to bacteria-associated tumors with significantly reduced off-target accumulation while increasing tumor localization, efficacy,...
Published: 3/1/2024   |   Inventor(s): Neil Forbes, Nele Van Dessel, John Klier, Shane Taylor, Vishnu Raman
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Therapeutics & prevention
Noncationic Nucleic Acid-Polymer Complexes for Nucleic Acid Delivery
PRODUCT OPPORTUNITIES Noncationic nucleic acid-polymer complexes for nucleic acid delivery Nucleic acid-polymer complexation kits for nucleic acid encapsulation and intracellular delivery Novel polymers for nucleic acid delivery with substantially reduced cytotoxicity PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES An efficient nucleic...
Published: 11/29/2024   |   Inventor(s): Sankaran Thayumanavan
Keywords(s):  
Category(s): Biotechnology, Healthcare, Nanotechnology, Life Sciences, Therapeutics & prevention
Cell-Membrane-Coated Polymeric Nanoparticles for Selective Intracellular Delivery of Therapeutics
­PRODUCT OPPORTUNITIES Cell-membrane-coated, cargo-encapsulated polymer nanoparticles as target-specific prodrugs PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Enhanced cellular uptake and endosomal escape, resulting in more efficient delivery of therapeutics Enhanced selectivity of intracellular delivery of therapeutics TECHNOLOGY...
Published: 8/10/2023   |   Inventor(s): Sankaran Thayumanavan
Keywords(s):  
Category(s): Healthcare, Life Sciences, Biotechnology, Nanotechnology, Therapeutics & prevention, Research tools
Novel Ferroptosis Inducing Compounds as Anti-cancer Agents
­PRODUCT OPPORTUNITIES • Ferroptosis inducing compounds for anti-cancer therapy • Ferroptosis inducers as research reagents PRODUCT OPPORTUNITIES ADVANTAGES • Highly target-specific • Can be used a complementary-mechanism-based therapy for front-line cancer treatments • Can...
Published: 8/10/2023   |   Inventor(s): Rachid Skouta, Thomas Dawson, Rohit Bhadoria
Keywords(s):  
Category(s): Chemicals, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
Demineralized Bone Paper and Applications Thereof
PRODUCT OPPORTUNITIES • Three-dimensional, living bone tissue grafts produced from stacked demineralized bone paper (DBP) for clinical applications • DBP-based high-throughput and high-content assay systems for bone disease drug discovery • Other DBP-containing products such as microfluidic bone marrow chips PRODUCT...
Published: 8/10/2023   |   Inventor(s): Jungwoo Lee, Jae-Hyuck Shim, Ryan Carpenter, Yongkuk Park, Jun-Goo Kwak
Keywords(s):  
Category(s): Biotechnology, Devices, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
Polymeric Nanoparticle-Based Antibiofilm Therapy
PRODUCT OPPORTUNITIES • Antimicrobial ointment for topical treatments • Antimicrobial injectable for in vivo treatments • Antibiofilm therapy ADVANTAGES • Non-antibiotic based • High efficacy against both planktonic bacteria and more drug-resistant bacterial biofilms •...
Published: 6/7/2024   |   Inventor(s): Vincent Rotello, Ryan Landis, Akash Gupta
Keywords(s):  
Category(s): Healthcare, Life Sciences, Biotechnology, Therapeutics & prevention
An Ex Vivo Method of Generating Super Regulatory T Cells as a Cell-based Therapy for the Prevention of Graft-vs-Host Disease
PRODUCT OPPORTUNITIES • Cell-based therapy for the prevention of graft-versus-host disease ADVANTAGES • Simple, well-defined generation of personalized, cell-based therapy for the prevention of graft-versus-host disease • Generation of super regulatory T cells with greatly improved suppressive capacity. TECHNOLOGY...
Published: 10/3/2023   |   Inventor(s): Lisa Minter, Gregory Tew, Emrah Ozay
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Research tools, Therapeutics & prevention
Novel Small Molecule Inhibitors of Caspase-6
PRODUCT OPPORTUNITIES Novel small molecule drug candidates for the treatment of Alzheimer’s and Huntington’s diseases PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Novel compositions of matter Small molecule compounds High caspase selectivity and specificity for caspase-6 TECHNOLOGY DESCRIPTION Caspase-6 is a...
Published: 8/10/2023   |   Inventor(s): Jeanne Hardy, Penchala Narasimharao Meka
Keywords(s):  
Category(s): Therapeutics & prevention, Life Sciences, Healthcare
A Novel Non-cationic Lipid-polymer-based Nanossembly for the Complexation and Intracellular Delivery of Nucleic Acids
PRODUCT OPPORTUNITIES Non-cationic lipid-polymer-nucleic acid nanoassembly for efficient delivery of nucleic-acid-based therapeutics such as siRNAs PRODUCT OPPORTUNITIES COMPETITIVE ADVANTAGES Non-cationic nucleic acid delivery system that mitigates carrier associated cytotoxicity Symbiotic, self-assembled delivery system with...
Published: 10/3/2023   |   Inventor(s): Sankaran Thayumanavan, Kingshuk Dutta
Keywords(s):  
Category(s): Biotechnology, Healthcare, Life Sciences, Nanotechnology, Therapeutics & prevention
1 2 3