Search Results - prostate

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SLCO1B3 Genotyping to Predict a Survival Prognosis of Prostate Cancer
Abstract: Steroid hormones have been implicated to play a fundamental role in the pathogenesis of prostate cancer. Polymorphisms in the genes that code for enzymes, or hormones involved in androgen regulatory pathway, reportedly influence risk for developing prostate cancer. Since many membrane transporters are modulators of steroid hormones absorption...
Published: 4/8/2024   |   Inventor(s): William Figg, Alex Sparreboom, Douglas Price, Akinobu Hamada
Keywords(s): Androgen-directed Therapy, Biomarkers, diagnostic, Figg, genetic markers, Genomics, Hormone-Refractory, personalized medicine, predictive markers, prognostic, PROSTATE, SLCO1B3
Category(s): TherapeuticArea > Endocrinology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Diagnostics, TherapeuticArea > Oncology
Novel Cancer Immunotherapy: A T Cell Receptor That Specifically Recognizes Common KRAS Mutations
Abstract: Several malignancies associated with a poor prognosis such as lung, pancreatic and colorectal cancers frequently harbor constitutively active KRAS mutants, which play a pivotal role in oncogenesis.  Currently, there are no potentially curative treatments against most mutant KRAS harboring cancers once they become metastatic and unresectable. ...
Published: 4/8/2024   |   Inventor(s): Qiong Wang, James Yang, Zhiya Yu
Keywords(s): Colorectal, Immunotherapy, KRAS, LUNG, oncogenesis, PANCREAS, PROSTATE, T cell, TCR
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
Transgenic Mouse Model of Human Basal Triple Negative Breast Cancer
Abstract: The NCI Laboratory of Cancer Biology and Genetics seeks parties interested in collaborative research to further develop this mouse model of triple-negative breast cancer (TNBC) to study cancer biology and for preclinical testing.  As a Research Tool, patent protection is not being pursued for this technology; more information to access this...
Published: 5/23/2024   |   Inventor(s): Jeffrey Green
Keywords(s): Mouse, Murine, PROSTATE, triple-negative breast cancer
Category(s): TherapeuticArea > Oncology, Application > Research Materials, Collaboration Sought > Licensing
Photoacoustic Imaging Using a Versatile Acoustic Lens
Applications:Photoacoustic imaging (also called optoacoustic or thermoacoustic imaging) has the potential to image animal or human organs with simultaneous high contrast and high spatial resolution. The photoacoustic signal is small and needs a mechanism to focus it on an image plane without degradation. This technology improves the signal to noise...
Published: 5/7/2024   |   Inventor(s): Vikram Dogra, Navalgund Rao, Wayne Knox
Keywords(s): Cancer, Diagnostic, Instrument, Instrumentation, Medical Device, Oncology, Prostate, Ultrasound, Ultrasound Imaging
Category(s): Imaging
Robot-Assisted Platform for Intratumoral Delivery (RAPID) System
ApplicationsThis technology relates to robot-assisted radioactive seed implantation for prostate brachytherapy. It is an automated system for delivery of seeds or other therapeutic or diagnostic capsules to internal organs of the patient’s body for radiation brachytherapy and includes a needling mechanism, a 2DOF robot, an ultrasound probe driver,...
Published: 5/7/2024   |   Inventor(s): Yan Yu, Wan Sing Ng, Yongde Zhang, Tarun Podder
Keywords(s): Cancer, Instrument, Instrumentation, Prostate, Therapy
Category(s): Surgical/Medical Device