Search Results - qiong+wang

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Therapeutic Inhibition of Molecular Drivers of Microglial Reactivity in Neurodegenerative Disease
It is estimated that over 55 million people have Alzheimer’s disease (AD) or other dementias, and despite their rapidly increasing burden, thus far there are no disease modifying therapeutics available. Novel therapeutic strategies are urgently needed to address the prevention and treatment of AD. Mounting evidence from large scale genetic studies...
Published: 2/14/2024   |   Inventor(s): Benjamin Readhead, Qi Wang, Diego Mastroeni, Eric Reiman
Keywords(s):  
Category(s): Life Science (All LS Techs), Neurodegenerative Disease Technologies
Novel Murine T-Cell Receptors for Treating Metastatic Thyroid Cancer
Abstract: The occurrence of thyroid cancer has been increasing in the United States. For some patients, with particularly advanced and metastatic cancer, current treatments such as thyroidectomy and adjuvant radioactive iodine therapy can lead to poor outcomes. Hence, there is a need for new thyroid cancer treatments. Researchers at the NCI have developed...
Published: 4/8/2024   |   Inventor(s): Kenichi Hanada, Qiong Wang, James Yang, Zhiya Yu
Keywords(s): act, adoptive cell therapy, Human Thyroglobulin, Immunotherapy, METASTATIC, T-cell Receptors, TCR, TCRs, Tg, THYROID CANCER, Yang
Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration
Novel Immunotherapy for Cancer Treatment: Chimeric Antigen Receptors Targeting CD70 Antigen
Abstract: Scientists at the NCI's Surgery Branch have developed anti-CD70 chimeric antigen receptors (CARs) to treat cancers. CD70 is an antigen that is expressed on a variety of human cancers such as renal cell carcinoma, glioblastoma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. The anti-CD70 CARs are hybrid proteins consisting of a receptor...
Published: 4/8/2024   |   Inventor(s): Qiong Wang, Zhiya Yu, James Yang
Keywords(s): CARS, CD70, chimeric antigen receptor, T-cell reprogramming
Category(s): TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing
Novel Cancer Immunotherapy: A T Cell Receptor That Specifically Recognizes Common KRAS Mutations
Abstract: Several malignancies associated with a poor prognosis such as lung, pancreatic and colorectal cancers frequently harbor constitutively active KRAS mutants, which play a pivotal role in oncogenesis.  Currently, there are no potentially curative treatments against most mutant KRAS harboring cancers once they become metastatic and unresectable. ...
Published: 4/8/2024   |   Inventor(s): Qiong Wang, James Yang, Zhiya Yu
Keywords(s): Colorectal, Immunotherapy, KRAS, LUNG, oncogenesis, PANCREAS, PROSTATE, T cell, TCR
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics
Design and Implementation of a Novel Portable C3S3 System
A portable, capillary-based cell culture platform for in vitro screening and viability assays that can produce an array of homogeneously sized cells for in vitro cell culture Background: Biosensors are devices that typically use biological molecules to detect other biological molecules or chemical substances. Detection of food-borne pathogens,...
Published: 11/11/2021   |   Inventor(s): Paul Blythe, Omowunmi Sadik, Qiong Wang
Keywords(s): #SUNYresearch, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Campus > Binghamton University