Search Results - genomics

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NU 2021-043 INVENTORS Chad A. Mirkin* Chi Huang BACKGROUND The use of CRISPR/Cas9 systems in genome editing has been limited by the inability to efficiently deliver the key editing...

Published: 7/3/2024 | Inventor(s):

Keywords(s): Genomics, Nanotechnology, Research tool

Category(s): Life Sciences > Therapeutics

SLCO1B3 Genotyping to Predict a Survival Prognosis of Prostate Cancer

Abstract: Steroid hormones have been implicated to play a fundamental role in the pathogenesis of prostate cancer. Polymorphisms in the genes that code for enzymes, or hormones involved in androgen regulatory pathway, reportedly influence risk for developing prostate cancer. Since many membrane transporters are modulators of steroid hormones absorption...

Published: 4/8/2024 | Inventor(s): William Figg, Alex Sparreboom, Douglas Price, Akinobu Hamada

Keywords(s): Androgen-directed Therapy, Biomarkers, diagnostic, Figg, genetic markers, Genomics, Hormone-Refractory, personalized medicine, predictive markers, prognostic, PROSTATE, SLCO1B3

Category(s): TherapeuticArea > Endocrinology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Diagnostics, TherapeuticArea > Oncology

Genomics-based Diagnostic Assay for Cancer

Abstract: Molecular profiling with high throughput assays has gained utility in the management of select cancer patients and several gene expression-based assays are now marketed for improved prognostic accuracy for patients with cancer. This technology describes a genomics based diagnostic assay for the diagnosis and prognosis of cancer patients. ...

Published: 4/8/2024 | Inventor(s): Steven Libutti, Mei He

Keywords(s): assay, CANCER, diagnostic, Genomics, PROGNOSIS

Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Licensing

Interactive Venn Diagram Software Designed for Microarray Analysis

Multiple conditions from any source, but designed for experiments involving microarrays, will produce (significant gene lists for arrays) lists from each condition, thus multiple lists. This Java® based software provides investigators with a method of displaying multiple conditions in a single graphic along with producing a text output of genes that...

Published: 7/25/2024 | Inventor(s): Daniel Sturdevant

Keywords(s): AD1XXX, AD3XXX, ADXXXX, AXXXXX, Bioinformatic, Bioinformatics, Genomic, Genomics, Java, Java-based, microarray, MICROARRAYS, software, Venn, Venn Diagram

Category(s): Collaboration Sought > Licensing

A Novel SUMO-like Gene for Type 1 Diabetes Susceptibility

Current State of the Art: Type 1 diabetes is an organ-specific autoimmune disease with aberrant immune responses to specific β-cell autoantigens. Prevention is important because diabetes interrupts normal development in children and carries the threat of severe complications in the most active period of life. Both environmental and genetic...

Published: 4/28/2020 | Inventor(s): Jin-Xiong She, Cong-Yi Wang

Keywords(s): Diabetes II, Genomics

Category(s): Diagnostics

catRAPID: large-scale sequence-based prediction of protein–RNA interactions

catRAPID estimates the binding propensity of protein-RNA pairs by using sequence information only. The algorithm can be used to predict protein associations with coding and non-coding transcripts. Predictions have proved very accurate (> 0.8) when validated by traditional Immunoprecipitation methods, like RIP and CLIP.Applications and Services:Identifies...

Published: 5/25/2020 | Inventor(s): Gian Gaetano Tartaglia, Federico Agostini, Davide Cirillo, Petr Klus

Keywords(s): Algorithms, Bioinformatics, Biomarkers, Genomics, Protein Structure & Design, Software

Category(s): Software & Algorithms

Method to identify new cancer drug targets in spliceosomal components

A new method and tools to map functional interactions of spliceosomal components accurately captures known, and identify new physical and functional associations important for health and disease.The method can be used to infer targets for alternative splicing regulation, and to study the effects on splicing of compounds directed to altered, or disease-associated...

Published: 2/19/2019 | Inventor(s): Juan Valcarcel, Juan Tejedor Vaquero, Panagiotis Papasaikas

Keywords(s): Algorithms, Bioinformatics, Genomics, Oncology

Category(s): Methodology, General Biology & Chemistry, Software & Algorithms