Search Results - gang+niu

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PET Imaging of lntegrin Expression with Suitably Labeled RGD Peptides for Multiple Diagnostic Purposes
This technology includes a number of dimeric RGD peptides which been developed and labeled with various PET isotopes (1BF, 68Ga, and 64Cu) for imaging integrin expression in cancer, inflammation, rheumatoid arthritis, myocardial infarct, stroke and traumatic injury. A number of these peptides have been translated into clinic for diagnosis and therapy...
Published: 8/12/2024   |   Inventor(s): Xiaoyuan (Shawn) Chen, Lixin Lang, Gang NIU
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, TherapeuticArea > Immunology, TherapeuticArea > Neurology
Evans Blue Dye Derivatives for Serum Albumin Labeling
The invention is an imaging agent and method of use for imaging blood pools and the lymphatic system. The imaging agent binds with high affinity to serum albumin, the most abundant serum protein, and can be tagged with several isotopes making it suitable for magnetic resonance imaging or positron emission tomographic imaging. To date, only very few...
Published: 10/28/2024   |   Inventor(s): Lixin Lang, Gang NIU, Xiaoyuan (Shawn) Chen
Keywords(s): Albumin, BLUE, CA2BXX, Evans Blue, fluorene-18, IA4AXX, LABELED, LABELING, Listed LPM Fenn as of 4/15/2015, Magnetic Resonance, PET, Pet imaging, positron emission, Positron-Emitting, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PXXXXX
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Application > Consumer Products, Application > Diagnostics, Application > Research Materials
Long Acting Therapeutic Conjugates with Evans Blue
This invention is a platform technology that pertains to the advantages of conjugating therapeutics to Evans Blue thus providing long lasting pharmacokinetic profiles by complexing with albumin. Notably, albumin bound therapeutic- or prodrug-Evans Blue conjugates provide a complex with a total molecular size above 60 kDa thus eliminating the risk for...
Published: 10/28/2024   |   Inventor(s): Gang NIU, Lixin Lang, Xiaoyuan (Shawn) Chen
Keywords(s): Albumin, blood brain barrier, CB1CXX, Central Nervous System, CONJUGATED, Conjugation, DIABETES, Evans Blue, IB6XXX, PXXXXX, RENAL CLEARANCE, therapeutics, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VPXXXX, WJXXXX, WKXXXX, YCXXXX
Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Neurology, TherapeuticArea > Cardiology, TherapeuticArea > Reproductive Health, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics