Search Results - david+shackelford

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The Use of Voltage Sensitive Mitochondrial Uncouplers as Selective Anti-Cancer Drugs (UCLA Case No. 2022-327)
UCLA researchers from the Department of Medicine have identified an anti-cancer drug that targets mitochondrial membrane potential to selectively kill tumor cells, showing efficacy for traditionally treatment-resistant lung cancers. BACKGROUND: Non-small cell lung cancer (NSCLC) is a devastating disease that will claim the lives of approximately 125,000...
Published: 2/17/2026   |   Inventor(s): David Shackelford
Keywords(s):  
Category(s): Therapeutics > Respiratory And Pulmonary, Therapeutics > Oncology
Improving Responses to mTOR Inhibitors (UCLA Case No. 2025-205)
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Published: 9/18/2025   |   Inventor(s): Milica Momcilovic, David Shackelford
Keywords(s):  
Category(s): Therapeutics > Respiratory And Pulmonary, Therapeutics > Oncology
Diagnosing Halogen Gas Exposure and Eosinophil-driven Diseases
Diagnosing Halogen Gas Exposure and Eosinophil-driven Diseases
Published: 3/4/2022   |   Inventor(s): David Ford, Mark Duerr, Jeffrey Teckman
Keywords(s):  
Category(s): Diagnostics
Positron Emission Tomography Guided Delivery of Mitochondrial Complex I Inhibitors (UCLA Case No. 2020-163)
UCLA researchers in the David Geffen School of Medicine Division of Pulmonary and Critical Care Medicine have developed a novel use of the positron emission tomography (PET) tracer [18F]FBnTP to guide the delivery of mitochondrial complex I inhibitors for the treatment of lung cancers.BACKGROUND: The mitochondria are essential regulators of cellular...
Published: 7/17/2025   |   Inventor(s): David Shackelford, Seyed Saman Sadeghi Hosseini, Milica Momcilovic
Keywords(s): Diagnostic Markers & Platforms, Imaging, Medical Imaging, PET, Respiratory & Pulmonary
Category(s): Medical Devices > Medical Imaging > PET, Therapeutics > Oncology, Therapeutics > Respiratory And Pulmonary
Diagnostic method for Biomarkers of Adverse Coronary Events
Title: Diagnostic method for biomarkers of adverse coronary events Category: Diagnostic NCS: Inventors: David A. Ford Summary: The present invention provides diagnostic methods for characterizing an individual's risk fordeveloping or having an adverse coronary event. More particular, the present invention isgenerally directed to characterizing an...
Published: 6/1/2021   |   Inventor(s): David Ford
Keywords(s):  
Category(s): Diagnostics