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PET Imaging of lntegrin Expression with Suitably Labeled RGD Peptides for Multiple Diagnostic Purposes
This technology includes a number of dimeric RGD peptides which been developed and labeled with various PET isotopes (1BF, 68Ga, and 64Cu) for imaging integrin expression in cancer, inflammation, rheumatoid arthritis, myocardial infarct, stroke and traumatic injury. A number of these peptides have been translated into clinic for diagnosis and therapy...
Published: 8/12/2024   |   Inventor(s): Xiaoyuan (Shawn) Chen, Lixin Lang, Gang NIU
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Cardiology, TherapeuticArea > Immunology, TherapeuticArea > Neurology
Metabolic activity diffusion imaging (MADI): dye-free, high-resolution MRI metabolic imaging
Summary The current technology is a contrast agent-free method of metabolic imaging based on detection of Na/K ATPase activity with MRI, that provides significantly higher resolution than current approaches such as PET. Technology Overview Measuring metabolic activity in vivo can facilitate diagnoses of disease states and therapeutic responses....
Published: 1/15/2024   |   Inventor(s): Gregory Wilson, Jeffrey Maki, Charles Springer, Jr., Xin Li, William (Bill) Rooney, Brendan Moloney, Wei Huang, Tom Barbara, Eric Baker
Keywords(s): Diagnostics, Imaging, Imaging - MRI, Software, Software - Other
Category(s): Imaging, Software
A Gamma-ray Photon Counting Detector Based on Side-readout of Monolithic Scintillator Layers
Researchers at the University of Arizona have developed a gamma-ray photon counting device that works similarly to PET, but with a novel architecture that improves the accuracy and speed in determining the location of the biological targets, and is less costly to manufacture. Background: Positron Emission Tomography (PET) is a common and reliable...
Published: 11/22/2023   |   Inventor(s): Lars Furenlid, Xin Li
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Imaging & Optics > Sensors and Detection
Evans Blue Dye Derivatives for Serum Albumin Labeling
The invention is an imaging agent and method of use for imaging blood pools and the lymphatic system. The imaging agent binds with high affinity to serum albumin, the most abundant serum protein, and can be tagged with several isotopes making it suitable for magnetic resonance imaging or positron emission tomographic imaging. To date, only very few...
Published: 7/25/2024   |   Inventor(s): Lixin Lang, Gang NIU, Xiaoyuan (Shawn) Chen
Keywords(s): Albumin, BLUE, CA2BXX, Evans Blue, fluorene-18, IA4AXX, LABELED, LABELING, Listed LPM Fenn as of 4/15/2015, Magnetic Resonance, PET, Pet imaging, positron emission, Positron-Emitting, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PXXXXX
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Application > Consumer Products, Application > Diagnostics, Application > Research Materials
Long Acting Therapeutic Conjugates with Evans Blue
This invention is a platform technology that pertains to the advantages of conjugating therapeutics to Evans Blue thus providing long lasting pharmacokinetic profiles by complexing with albumin. Notably, albumin bound therapeutic- or prodrug-Evans Blue conjugates provide a complex with a total molecular size above 60 kDa thus eliminating the risk for...
Published: 7/25/2024   |   Inventor(s): Gang NIU, Lixin Lang, Xiaoyuan (Shawn) Chen
Keywords(s): Albumin, blood brain barrier, CB1CXX, Central Nervous System, CONJUGATED, Conjugation, DIABETES, Evans Blue, IB6XXX, PXXXXX, RENAL CLEARANCE, therapeutics, VCXXXX, VDXXXX, VEXXXX, VFXXXX, VPXXXX, WJXXXX, WKXXXX, YCXXXX
Category(s): Collaboration Sought > Licensing, Application > Vaccines, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Neurology, TherapeuticArea > Cardiology, TherapeuticArea > Reproductive Health, TherapeuticArea > Endocrinology, Application > Consumer Products, TherapeuticArea > Dental, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics
Intelligent Multi-Beam Medium Access Control in Ku-Band for Mission-Oriented Mobile Mesh Networks
­ The Problem: There are existing similar technologies, but these technologies are not designed for mobile mission-oriented applications. The use of Ku-band frequency on two separate information transmission levels reduces interference common with current multi-beam antennas. Also, the Ku-band frequency is not the currently used frequency range...
Published: 2/27/2023   |   Inventor(s): Fei Hu, xI Li, Sunil Kumar
Keywords(s):  
Category(s): Technology Classifications > Communication
A Mechanism and Method for Synthesis of a 2-D Gamma-ray Pinhole Projection Image from a Plurality of Slit Projection Images
This invention is a 3D medical imaging technique that incorporates single photon emission computed tomography (SPECT) to image radioisotope distributions, which are generally used to detect/monitor cancer, drug delivery, etc. This imaging technique uses SPECT to take 2D and 3D tomographic images of radioisotope distributions, both of which can be analyzed...
Published: 4/3/2023   |   Inventor(s): Lars Furenlid, Xin Li
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Close Range PET
This invention involves moving the detector ring of a PET system closer to the patient while improving the spatial resolution and reducing the blurriness of resulting images. By moving the detector module closer, the quantity of samples tested, and the solid angle covered by the scanner are increased. Background: Currently, PET system’s sensitivity...
Published: 8/16/2024   |   Inventor(s): Xin Li
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Medical Imaging
Network Algorithm for Communication over Lossy Connections
Improves Transmission of Data without Resending Lost InformationThis communication algorithm combines elements of fountain and network coding to achieve low delay, high throughput connections while allowing multiple uncoordinated source transmission of the same file to the same destination. When communicating data over lossy networks (such as Wi-Fi,...
Published: 6/27/2021   |   Inventor(s): Dapeng Wu, Qiuyuan Huang, Xin Li, Kairan Sun
Keywords(s): erasure channel, Fountain code, network coding
Category(s): Technology Classifications > Engineering > Electrical
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