Search Results - mri+diagnostic

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MRI-Based Method for Characterizing Axonal Microstructure in Traumatic Brain Injury
Abstract: Neurites of the central nervous system can be conceptualized as cylindrical pores with finite lengths and radii. In response to physical trauma, axons may assume a “beaded” morphology which alters their ability to conduct electrical impulses, impairing brain function. These microstructural changes are thought to underlie some of the cognitive...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Dan Benjamini, Michal Komlosh
Keywords(s): Magnetic Resonance Imaging, MRI, MRI diagnostic, Neurites, Peripheral Nervous System, PNS, TBI, Traumatic Brain Injury
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology
MADCO-Accelerated Multidimensional Diffusion MRI
Abstract: Although multidimensional diffusion/relaxation NMR experiments are widely used in materials sciences and engineering applications, preclinical and clinical MRI applications of these techniques were not feasible. Moreover, higher-field MRI scanners posed another obstacle to translation of this NMR method. Their specific absorption rate (SAR)...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Dan Benjamini
Keywords(s): Basser, Biomarkers, Diffusion MRI, IMAGING, Marginal-Distributions, MRI, MRI diagnostic, Multidimensional-NMR, NMR-Spectroscopy, Relaxometry Diffusometry, T1, T2
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, TherapeuticArea > Immunology, Collaboration Sought > Licensing, Collaboration Sought > Materials Available, Application > Diagnostics
Quantitative In Vivo Methods for Measuring Brain Networks
Abstract: The pattern or latency connectome was hypothesized to change in physiological development and disease.  For example, in amyotrophic lateral sclerosis (ALS), large diameter axons are damaged selectively – while in autism, small-diameter axons may be over-expressed. These anatomical changes are expected to alter the latency connectome or pattern...
Published: 4/8/2024   |   Inventor(s): Peter Basser
Keywords(s): Axon diameter distribution, connectome, DTI Tractography, Magnetic Resonance Imaging, MRI, MRI diagnostic
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Diagnostics
Magnetic Resonance Specimen Evaluation Using Multiple Pulse Field Gradient Sequences
Abstract: Researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) developed an MRI-method that is based on the acquisition of multiple pulsed field gradient (m-PFG) rather than single-pulsed field gradient (s-PFG) MRI sequences. In particular, double PFG (dPFG) MRI sequences offer higher sensitivity...
Published: 4/8/2024   |   Inventor(s): Peter Basser, Evren Ozarslan
Keywords(s): Axon diameter distribution, double PFG, d-PFG, MRI diagnostic, Multiple Pulsed Field Gradient
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology