Search Results - luyang+liu

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Individualized intranasal delivery system for direct pharmaceutical administration to the brain
The technology involves a customizable nasal delivery device for precise administration of medications directly to the brain, bypassing traditional barriers. It uses imaging techniques for optimal placement, enhancing drug delivery efficiency and minimizing systemic side effects. Background Oral administration remains the predominant method for drug...
Published: 10/11/2024   |   Inventor(s): Hugh Smyth, Robert Williams, Zachary Warnken, Yang Lu
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Medical technology > Medical devices
Steric Hindrance Effect of Additives for Tuning the Perovskite Crystal Orientation (Case No. 2024-023)
Summary: UCLA Researchers in the Department of Materials Science and Engineering have developed a method to tune perovskite crystal orientation for increased performance, energy efficiency, and reduced material defect with a variety of field applications, including solar cells and LEDs. Background: Perovskite holds considerable promise as a highly...
Published: 10/25/2024   |   Inventor(s): Yang Yang, Chunqing Ma, Haoxiang Duan, Dong Meng
Keywords(s): Energy Efficiency, energy-efficient, Imaging, Liquid-Crystal Display, Nanocrystal, OLED, Optoelectronics, organic photo detector, organic photovoltaics, perovskite, perovskite devices, perovskite solar cell, photodetection, Solar Cell, X-ray detectors
Category(s): Chemical > Chemical Processing & Manufacturing, Energy & Environment > Energy Efficiency, Energy & Environment, Materials > Composite Materials, Optics & Photonics, Optics & Photonics > Fiber Optics, Materials > Functional Materials
Revolutionizing surgical interventions: the steerable flexible curved-drilling robot (SFCR)
­The Steerable Flexible Curved-Drilling Robot (SFCR) is an innovative medical device designed to enhance precision in surgical drilling through complex bone structures. This cutting-edge technology features a dual-tube system with a flexible drive shaft, enabling controlled, curved drilling paths that navigate around obstacles like nerves and low-density...
Published: 8/2/2024   |   Inventor(s): Farshid Alambeigi, Yang Liu
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
2023-087 Thiophene Configurable Amorphous Small Molecular Hole Transporting Material for Efficient and Stable Perovskite Solar Cell
Summary: UCLA researchers in the Department of Materials Science and Engineering have invented a series of hole transporting materials that have enabled among the highest recorded power conversion efficiencies for perovskite solar cells while maintaining high device stability and low cost. Background: Perovskite solar cells (PSCs) are an emerging...
Published: 6/25/2024   |   Inventor(s): Yang Yang, Dong Meng
Keywords(s): buffer layer, charge collection, charge collection efficiency, charge extraction, charge-transfer, device architectures, device stability, hole transporting material, hydrophobicity, interfacial layer, ion-migration, n-i-p device, perovskite, Perovskite Lead(II) Iodide, perovskite solar cell, photostability, p-i-n device, power conversion efficiency, radiosurgery, Silicon Working Electrode Perovskite (Structure), spinal surgery, thermal stability
Category(s): Chemical, Electrical, Energy & Environment > Energy Generation > Solar, Materials, Materials > Functional Materials, Electrical > Electronics & Semiconductors
DROPLET-ELECTROPHORESIS DEVICES AND RELATED METHODS
­DROPLET-ELECTROPHORESIS DEVICES AND RELATED METHODS Researchers at UC Berkeley have developed a novel method for comprehensively profiling the proteomes of single cells. Genomics (DNA) and transcriptomics (RNA) sequencing is one of the cornerstones of our modern-day understanding of the genetic blueprint of life. Furthermore, sequencing and...
Published: 4/22/2024   |   Inventor(s): Amy Herr, Yang Liu
Keywords(s): Microfluidics, Protein, Single Cell Analysis
Category(s): Technology Classifications > Engineering
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 6/5/2024   |   Inventor(s): Li Liu, Jingmin Shu
Keywords(s):  
Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices
An OCT method to improve scleral lens fitting
Summary The current technology allows for accurate and objective 3-dimensional (3D) mapping of the external limbus, which could ultimately improve the process of scleral lens fitting. Technology Overview Rigid scleral lenses are difficult to fit to patients because they must rest on the eye but vault over the cornea and the limbus, which is the transition...
Published: 1/5/2024   |   Inventor(s): David Huang, Yan Li, Clara Llorens Quintana
Keywords(s): Imaging, Imaging - Other, Software, Software - Diagnostic/Detection
Category(s): Imaging, Software
High-Throughput Direct-Measurement of Telomere Length
Telomeres are linear chromosome end-capping repetitive DNA sequences. They serve to protect the ends of chromosomes from undesirable fusion events, thus integrity and length are crucial for stability. Natural attrition as well as mutations can affect telomere integrity and length resulting in chromosome instability, senescence, cell death and human...
Published: 8/14/2023   |   Inventor(s): Julian Chen, Yang Li, Dhenugen Logeswaran
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
Learning Sparse Features for Self-Supervised Learning with Contrastive Dual Gating
The success of conventional supervised learning relies on large-scale labeled datasets to achieve high accuracy. However, annotating millions of data samples is labor-intensive and time-consuming. This promotes self-supervised learning as an attractive solution with artificial labels being used instead of human-annotated ones for training. Contrastive...
Published: 6/2/2023   |   Inventor(s): Jae-Sun Seo, Jian Meng, Li Yang, Deliang Fan
Keywords(s): Algorithm Development, Machine Learning, Performance Optimization, PS-Computing and Information Technology
Category(s): Computing & Information Technology, Physical Science
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