Search Results - lina+karam

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Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 11/18/2025 | Inventor(s): Feng Yan, Lin Li

Keywords(s):

Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Clonal Spodoptera Frugiperda Cell lines for Enhanced Expression

This technology includes Spodoptera frugiperda (Sf9) cells which were developed to produce recombinant adeno-associated virus. The cells maintain a copy of the vector genome and for production, require infection with a single baculovirus that expresses either structural and nonstructural proteins to produce rAAV, or the non-structural (Rep) proteins...

Published: 8/12/2024 | Inventor(s): Lina Li, Robert Kotin

Keywords(s):

Category(s): Application > Research Materials, Application > Therapeutics, Collaboration Sought > Licensing, ResearchProducts > Plasmids/Vectors

Capsid-Free AAV Vectors for Gene Delivery and Their Use for Gene Therapy

The invention concerns novel capsid-free AAV vectors that can be used for gene delivery and gene therapy applications. The invention provides for a linear nucleic acid molecule comprising in this order: a first adeno-associated virus (AAV) inverted terminal repeat (ITR), a nucleotide sequence of interest, and a second AAV ITR, wherein said nucleic acid...

Published: 10/28/2024 | Inventor(s): Lina Li, Luis Garcia, Cyriaque Beley, Thomas Voit, Robert Kotin

Keywords(s): AAV, Cell, Clonal, Containing, DNA, GB2AXX, Lines, Listed LPM Reichman as of 4/15/2015, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Rescueable, Sf9, STABLE, Vector, VPXXXX, WJXXXX, XEXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Dental, TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 1/9/2026 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Cold atmospheric plasma-stimulated media for treating cancers

For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Zhitong Chen, Xiaoqian Cheng, Li Lin

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics

Fearture Corrections and Regeneration for Robust Sensing, Computer Vision, and Classfification

Background Deep neural networks (DNNs) have become the standard go-to solution for the majority of computer vision applications for the ease of design of such networks. Challenging computer vision tasks like image classification and object recognition, previously regarded to be extremely difficult have seen great results due to the use of DNNs. In...

Published: 2/13/2025 | Inventor(s): Lina Karam, Tejas Borkar

Keywords(s): Artificial Intelligence, Medical Devices and Imaging, Networks, IT, Software and Communication, Sensors

Category(s): Computing & Information Technology

Twistron Mechanical Energy Harvesters

Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, automotive technologies, and the extraction of energy from ocean waves. Until now, few harvesters have been flexible enough to be used as yarns in textiles, and the performance of such yarns has been...

Published: 6/26/2024 | Inventor(s): Shi Hyeong Kim, Carter Haines, Na Li, Keon Jung Kim, Tae Jin Mun, Changsoon Choi, Jiangtao Di, Shaoli Fang, Seon Jeong Kim, Ray Baughman

Keywords(s): Automotive, Carbon Nanomaterials, Carbon Nanotubes, Electronics, Energy, Cleantech & Environmental, Engineering & Physical Sciences, Renewable Energy, Sensors & Controls, Textiles, Wireless

Category(s): Nanotechnology

Intelligent Textiles Prepared from Nanofiber Yarns and Polymer Fiber Actuators

While there has always been a desire for smart textiles, including fabrics which adapt depending on environmental stimuli, it has yet to be effectively accomplished due to the lack of suitable materials. These polymer fiber actuators have enabled the creation of fabrics that can reversibly change properties such as porosity, shape, color and texture....

Published: 4/22/2021 | Inventor(s): Ray Baughman, Ozer Goktepe, Fatma Goktepe, Na Li, Marcio Lima, Carter Haines, Shaoli Fang

Keywords(s): Engineering & Physical Sciences, Industrial & Manufacturing, Nanotechnology, Polymers, Textiles

Category(s): Materials

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