Search Results - shi+hyeong+kim

4 Results Sort By:
Compounds that Interfere with the Androgen Receptor Complex
Abstract: Investigators at the National Institutes of Health (NIH) have discovered compounds that have potential as novel anti-androgen therapeutics. The immunophilin protein FKBP52 is part of a protein complex that helps fold the androgen receptor (AR) protein, a target for treating prostate cancer, and enhances its activity. Disruption of the FKPB52-AR...
Published: 4/8/2024   |   Inventor(s): Leonard Neckers, Jane Trepel Neckers, Yeong Kim, Aki Iwai, Yangmin Ning, Marc Cox, Johanny Meneses De Leon, Heather Balsiger, Robert Fletterick
Keywords(s): androgen receptor protein, DIABETES, PROSTATE CANCER
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Endocrinology
Treatment of Prostate Cancer Using Anti-androgen Small Molecules
Abstract: Castrate-resistant prostate cancer (CRPC) is characterized by androgen-independent cancer cells that have adapted to the depletion of hormones and continue to grow. Abnormal androgen receptor signaling is known to drive advanced castrate-resistant prostate cancer. The small molecule compounds of this invention are antiandrogens that target...
Published: 4/8/2024   |   Inventor(s): Jane Trepel Neckers, Yeong Kim, Sunmin Lee, Vineet Kumar, Sanjay Malhotra
Keywords(s): Antiandrogen, castrate resistant, CRPC, PROSTATE CANCER, small molecule, steroid hormone receptor.
Category(s): Application > Therapeutics, Collaboration Sought > Licensing, TherapeuticArea > Oncology
2021-225 An Innovative Dielectric Elastomer and Multilayer Dielectric Elastomer Actuator with High Electrically Induced Actuation Strains
SUMMARY: UCLA researchers in the Department of Materials Science and Engineering have developed a dielectric elastomer and layering process that can produce actuators capable of high strain and high frequency actuation. BACKGROUND: Dielectric elastomers (DE) can act as deformable capacitors that can generate a mechanical movement in response to an...
Published: 7/19/2023   |   Inventor(s): Qibing Pei, Erin Askounis, Ye Shi
Keywords(s): Actuator, Capacitor, Dielectric, Elastomer, Electroactive Polymers, Flexible Electronics, Functional Materials, Haptic Technology, Haptic Technology Robotic Surgery, Robotics, Sensors, Smartphone
Category(s): Software & Algorithms, Software & Algorithms > Bioinformatics, Life Science Research Tools, Software & Algorithms > Programs
Twistron Mechanical Energy Harvesters
Mechanical energy harvesters are needed for diverse applications, including self-powered wireless sensors, structural and human health monitoring systems, automotive technologies, and the extraction of energy from ocean waves. Until now, few harvesters have been flexible enough to be used as yarns in textiles, and the performance of such yarns has been...
Published: 6/26/2024   |   Inventor(s): Shi Hyeong Kim, Carter Haines, Na Li, Keon Jung Kim, Tae Jin Mun, Changsoon Choi, Jiangtao Di, Shaoli Fang, Seon Jeong Kim, Ray Baughman
Keywords(s): Automotive, Carbon Nanomaterials, Carbon Nanotubes, Electronics, Energy, Cleantech & Environmental, Engineering & Physical Sciences, Renewable Energy, Sensors & Controls, Textiles, Wireless
Category(s): Nanotechnology