Search Results - hong-gang+wang

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A Low-Cost GPS Spoofing Detector and Spoofer Localizer

The Challenge Thirty-one satellites currently in orbit contribute to the Global Positioning System. These satellites are used to calculate the longitude, latitude, and altitude of users. However, the GPS system is vulnerable to spoofing attacks that can migrate the user from the actual signal to the spoofing signal. These attacks can disrupt operations...

Published: 7/19/2024 | Inventor(s): Yaling Yang, Shinan Liu, Gang Wang

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Category(s): Technology Classifications > Communication, Technology Classifications > Software, Technology Classifications > Consumer Products, Technology Classifications > Transportation, Technology Classifications > Security

Fragment Evolution via Kinetic Target-Guided Synthesis for the Identification of Potent Bcl-2 Modulators

Competitive Advantages Increased throughput by 200-fold Can be applied to any biological target Identifies previously "undruggable" targets Increased sensitivity Summary USF researchers have developed an improved kinetic TGS sample detection method. This technology specifically targets modulating proteins of the Bcl-2 family....

Published: 8/26/2023 | Inventor(s): David Flanigan, Hong-Gang Wang, Iredia Iyamu, Jeremiah Tipton, Katya Nacheva, Kenichiro Doi, Megan Barber, Niranjan Namelikonda, Sameer Kulkarni, Roman Manetsch

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Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Cancer, Technology Classifications > Medical > Pharmaceuticals

Acylsulfonamides and Processes for Producing the Same

Competitive Advantages Selective triggering of apoptotic pathway in cancer cells Enhances the body’s natural defense against tumors Decreased damage to healthy cells and tissues Summary USF scientists have designed a novel compound class that shows promise to specifically target the anti-apoptotic Bcl-2 family of proteins,...

Published: 8/27/2023 | Inventor(s): Hong-Gang Wang, Jiazhi Sun, Sameer Kulkarni, Xiangdong Hu, Roman Manetsch

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Category(s): Technology Classifications > Cancer, Technology Classifications > Cancer > Cancer Diagnostics

Chips and Fabrication Methods for Rotation of Live Single Cells or Cell Clusters in Live Cell Computed Tomography

High-dimensional single cell visualization technologies are redefining the way we view and understand biological systems, particularly when identifying and analyzing cancer cells. Some cell defects on the surface or in the interior of a cell just can't be properly evaluated in two dimensional microscopy. However, to completely visualize and quantitatively...

Published: 2/23/2023 | Inventor(s): Hong Wang, Deirdre Meldrum, Rishabh Shetty, Laimonas Kelbauskas, Shih-Hui (Joseph) Chao

Keywords(s): Bio-Technology, Mechanical and Manufacturing, Medical Devices and Imaging

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Imaging, Life Science (All LS Techs)

Chips and Fabrication Methods for Capture and Rotation of Live Single Cells or Cell Clusters

High-dimensional single cell visualization technologies, such as live-cell computed tomography (CT), are redefining the way we view and understand biological systems, particularly when identifying and analyzing cancer cells. Some cell defects on the surface or in the interior of a cell just can't be properly evaluated in two dimensional microscopy....

Published: 2/23/2023 | Inventor(s): Deirdre Meldrum, Roger Johnson, Iniyan Soundappa Elango, Andrew Shabilla, Hong Wang, Matthew Stanley, Jakrey Myers, Laimonas Kelbauskas, Dean Smith, Pimwadee Limsirichai

Keywords(s): Bio-Technology, Drug Screening, Environmental, Materials and Electronics, Medical Devices and Imaging

Category(s): Life Science (All LS Techs), Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Imaging

Aptamer-siRNA chimera targeting RORγt in Th17 cells for topical therapy of psoriasis

Summary Researchers at Oregon Health & Science University and at the Portland VA Medical Center have discovered and validated a novel aptamer-siRNA chimera targeting RORγt in Th17 cells for topical treatment of psoriasis. Technology Overview Th17 cells produce several inflammatory cytokines, including IL-17, IL-17F, IL-22 and IL-21 which...

Published: 9/22/2022 | Inventor(s): Cong-Qiu Chu, Gang Wang

Keywords(s): Therapeutics - Dermatology

Category(s): Therapeutics