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Fragment Evolution via Kinetic Target-Guided Synthesis for the Identification of Potent Bcl-2 Modulators
­Competitive Advantages Increased throughput by 200-fold Can be applied to any biological target Identifies previously "undruggable" targets Increased sensitivity Summary USF researchers have developed an improved kinetic TGS sample detection method. This technology specifically targets modulating proteins of the Bcl-2 family....
Published: 8/26/2023   |   Inventor(s): David Flanigan, Hong-Gang Wang, Iredia Iyamu, Jeremiah Tipton, Katya Nacheva, Kenichiro Doi, Megan Barber, Niranjan Namelikonda, Sameer Kulkarni, Roman Manetsch
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Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Cancer, Technology Classifications > Medical > Pharmaceuticals