Search Results - jeremiah+tipton

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Fragment Evolution via Kinetic Target-Guided Synthesis for the Identification of Potent Bcl-2 Modulators
­Competitive Advantages Increased throughput by 200-fold Can be applied to any biological target Identifies previously "undruggable" targets Increased sensitivity Summary USF researchers have developed an improved kinetic TGS sample detection method. This technology specifically targets modulating proteins of the Bcl-2 family....
Published: 8/26/2023   |   Inventor(s): David Flanigan, Hong-Gang Wang, Iredia Iyamu, Jeremiah Tipton, Katya Nacheva, Kenichiro Doi, Megan Barber, Niranjan Namelikonda, Sameer Kulkarni, Roman Manetsch
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Category(s): Technology Classifications > Medical > Biotechnology, Technology Classifications > Cancer, Technology Classifications > Medical > Pharmaceuticals
Photo-Labels with Enhanced Ambient Light Stability and Water Solubility
Competitive Advantages Ambient light stability Improved aqueous solubility Efficient in photo-labelling target proteins Summary Our inventors have synthesized an ambient-light stable photo-label without compromising the photo-activated insertion reactivity. The new synthesized photo-label is effective for photo-affinity labeling...
Published: 8/25/2023   |   Inventor(s): Roman Manetsch, Arun Kumar, Jeremiah Tipton
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Category(s): Technology Classifications > Advance Materials, Technology Classifications > Engineering