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Search Results - sameer+kulkarni
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Fragment Evolution via Kinetic Target-Guided Synthesis for the Identification of Potent Bcl-2 Modulators
Competitive Advantages Increased throughput by 200-fold Can be applied to any biological target Identifies previously "undruggable" targets Increased sensitivity Summary USF researchers have developed an improved kinetic TGS sample detection method. This technology specifically targets modulating proteins of the Bcl-2 family....
Published: 8/26/2023
|
Inventor(s):
David Flanigan
,
Hong-Gang Wang
,
Iredia Iyamu
,
Jeremiah Tipton
,
Katya Nacheva
,
Kenichiro Doi
,
Megan Barber
,
Niranjan Namelikonda
,
Sameer Kulkarni
,
Roman Manetsch
Keywords(s):
Category(s):
Technology Classifications > Medical > Biotechnology
,
Technology Classifications > Cancer
,
Technology Classifications > Medical > Pharmaceuticals
Acylsulfonamides and Processes for Producing the Same
Competitive Advantages Selective triggering of apoptotic pathway in cancer cells Enhances the body’s natural defense against tumors Decreased damage to healthy cells and tissues Summary USF scientists have designed a novel compound class that shows promise to specifically target the anti-apoptotic Bcl-2 family of proteins,...
Published: 8/27/2023
|
Inventor(s):
Hong-Gang Wang
,
Jiazhi Sun
,
Sameer Kulkarni
,
Xiangdong Hu
,
Roman Manetsch
Keywords(s):
Category(s):
Technology Classifications > Cancer
,
Technology Classifications > Cancer > Cancer Diagnostics