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Search Results - haoxin+chen
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Fully Human Antibody Targeting Tumor Necrosis Factor Receptor Type 2 (TNFR2) for Cancer Immunotherapy
Abstract: Tumor necrosis factor receptor type 2 (TNFR2)-expressing regulatory T cells (Tregs), present in the tumor microenvironment, play an important role in tumor immune evasion. TNFR2 plays a crucial role in stimulating the activation and proliferation of Tregs, a major checkpoint of antitumor immune responses. In addition to its expression on Tregs,...
Published: 5/22/2024
|
Inventor(s):
Joost Oppenheim
,
Dimiter Dimitrov
,
De Yang
,
Xin Chen
,
Zhongyu Zhu
Keywords(s):
ADCC
,
ANTIBODY
,
Antibody-dependent Cellular Cytotoxicity
,
CANCER
,
Immunotherapy
,
Oppenheim
,
TNFR2
,
Tregs
,
Tumor Necrosis Factor Receptor Type 2
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
Application > Therapeutics
,
TherapeuticArea > Oncology
Novel Multi-Omics Aging Clock
A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...
Published: 3/12/2024
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Inventor(s):
George Sutphin
,
Samuel Freitas
,
Megha Padi
,
Chen Chen
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Biomarkers
,
Technology Classifications > Research Tools > Animal Models
,
Technology Classifications > Research Tools > Screening assays
,
Technology Classifications > Research Tools > Simulators and Modeling Tools
Autonomous Drone for railroad track inspection
Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...
Published: 3/15/2023
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Inventor(s):
Yu Qian
,
Yi Wang
,
Chen Chen
Keywords(s):
autonomous drone
,
flight control
,
image processing
,
railroad track inspection
,
self-navigation
Category(s):
Engineering and Physical Sciences
Engineered globular endolysin, a highly potent antibacterial enzyme for multidrug resistant Gram-negative bacteria
[Licensing negotiation in progress] [Invitation for Expression of Interest- Deadline 2 July 2021] We are inviting expressions of interest (EoI) for commercializing “Engineered Globular Endolysin, a Highly Potent Antibacterial Enzyme for Multidrug Resistant Gram-Negative Bacteria” technology. The innovation is developed by Professor XIA...
Published: 10/17/2023
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Inventor(s):
Jiang XIA
,
Shui Yee LEUNG
,
Xi CHEN
,
Miao LIU
Keywords(s):
Category(s):
Biotechnology
,
Therapeutics
2015-671 Underground Shafts for Hydrogen Storage
SummaryResearchers at UCLA have developed an underground drilled shaft concept for storage of hydrogen or other gases.BackgroundOne challenge in creating a hydrogen economy is developing hydrogen gas storage solutions. Increased interest has helped the global hydrogen storage market grow to $2.6 billion in 2016, and it is expected to reach over $5...
Published: 7/19/2023
|
Inventor(s):
Adrienne Lavine
,
Hossein Kavehpour
,
Dante Simonetti
,
Richard Wirz
,
Chen Chen
,
Gabriela Bran
,
Gopinath Warrier
,
Hamarz Aryafar
,
Jonathon Kennedy
,
Joshua Jordan
,
Keith Lovegrove
Keywords(s):
Energy & Water
Category(s):
Energy & Environment > Energy Generation > Solar
,
Energy & Environment > Energy Storage
Microsecond Time-Resolved Mass Spectrometry [ID 10004]
OverviewAt this time the predominant method for a pharmaceutical chemist to characterize reaction kinetics is to employ spectroscopy. The main issue with this technique is that spectroscopy produces an absorption/Emission spectrum and it is possible for multiple different compounds to have the same spectrum peak, making it difficult to differentiate....
Published: 10/13/2020
|
Inventor(s):
Hao Chen
,
Zhixin Miao
Keywords(s):
Category(s):
Physical Science > Chemistry
On-line and Off-line Coupling of Electorchemistry (EC) with Mass Spectrometry by Liquid Sample DESI OU [ID: #09030]
A variety of ambient ionization methods have been introduced, including desorption electrospray ionization (DESI). DESI is a representative method for ambient mass spectrometry. It has been shown to be useful in providing a rapid and efficient means of desorbing and ionizing a variety of target compounds of interest under ambient conditions. In U.S....
Published: 2/23/2022
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Inventor(s):
Hao Chen
,
Jiwen Li
,
Zhixin Miao
Keywords(s):
Category(s):
Physical Science > Chemistry
,
Life Science > Mass Spectrometry
Analysis of Liquid Samples by Desorption Electrospray Ionization-Mass Spectrometry (DESI-MS) [ID 08023]
OverviewMass Spectrometry (MS) works by converting molecules into ions which can then be detected and analyzed. DESI-MS applications were previously restricted to analyzing solid samples on surfaces. Researchers at Ohio University have discovered a novel application of DESI by fostering the technology to analyze liquid samples. In this technique, titled...
Published: 10/13/2020
|
Inventor(s):
Hao Chen
Keywords(s):
Category(s):
Life Science > Mass Spectrometry
A Novel, Low-Cost Substrate System for Gas-Phase or Multiphase Analyte Detection Using Surface-Enhanced Raman Scattering (SERS)
PRODUCT OPPORTUNITIES• SERS substrate kits for gas-phase or multiphase analyte detection• SERS-based gas-phase or multiphase analyte detection servicesPRODUCT OPPORTUNITIESADVANTAGES• Simple and low-cost substrate fabrication• Sensitive gas-phase and multiphase analyte detection • In situ detection...
Published: 8/10/2023
|
Inventor(s):
Lili He
,
Haoxin Chen
Keywords(s):
Category(s):
Research tools
,
Food technology & plant science
,
Nanotechnology
Image-Guided Microwave Therapy
This invention seeks to combine an improved method of treating T1 to T4 breast cancer through a tumor treatment system that both treats and monitors tumor cells with a combination of focused microwave therapy (FMT) and spectroscopic thermoacoustic imaging (STI). The goal is to employ heat to destroy or reduce tumors while minimizing invasiveness and...
Published: 11/16/2023
|
Inventor(s):
Russell Witte
,
Hao Xin
,
Diego Martin
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Healthcare Portfolios > Oncology
,
Technology Classifications > Medical Devices > Therapeutic
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