Search Results - griffithsin

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Anti-Viral Polypeptide Griffithsin: Compounds, Compositions, and Methods of Use
Abstract: This technology describes additional methods of using the griffithsin anti-viral polypeptides described in related NCI invention (reference number E-106-2003).  Specifically, this invention describes the use of GRFT to inhibit viral infection of hepatitis C viral infection, a severe acute respiratory syndrome (SARS) viral infection, an H5N1...
Published: 4/8/2024   |   Inventor(s): Barry O'Keefe, James McMahon, Toshiyuki Mori
Keywords(s): Anti-Viral, Corona virus, Ebola, Griffithsin, INFLUENZA, O’Keefe, SARS
Category(s): TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Application > Therapeutics, Collaboration Sought > Licensing
Griffithsin-Based Anti-viral Therapeutics with Improved Stability and Solubility
Abstract: Griffithsin is a potent anti-viral protein with activity against HIV, HCV, Sars, HSV 1 & 2 and other viruses.  It is active against HIV and HCV at picomolar concentrations.  Griffithsin is moving into clinical trials as an anti-HIV microbicide. Based on the structure of griffithsin and the necessities of pharmaceutical product development...
Published: 7/16/2024   |   Inventor(s): Barry O'Keefe, Kenneth Palmer, Tinoush Moulaei, Lisa Rohan, Joshua Fuqua, Lindsay Kramzer
Keywords(s): Anti-Viral, cnidarin, Griffithsin, HCV, HIV, HSV, SARS
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease
An Anti-Viral Polypeptide: Griffithsin
Abstract: Virus entry into a susceptible host cell is the first step in the formation of all viral diseases. Controlling viral infections by disrupting viral entry is advantageous for antibody-mediated neutralization by the host’s immune system and as a preventive and therapeutic antiviral strategy. Plant-derived carbohydrate-binding proteins...
Published: 4/8/2024   |   Inventor(s): Michael Boyd, Toshiyuki Mori, Barry O'Keefe
Keywords(s): Griffithsin, O'Keefe, SARS, Severe acute respiratory syndrome
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing