Search Results - species

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Nucleic Acid Primers and Probes for Detecting Ebola Virus (species Zaire ebolavirus)
The 2014-2016 Ebola Virus Disease (EVD) outbreak in West Africa was the largest in history, causing more than 28,000 suspected, probable, and confirmed infections and more than 11,000 deaths across nine countries. CDC scientists designed nucleic acid primers and probes which can be used in a sensitive test for detecting all known strains of Ebola virus...
Published: 10/28/2024   |   Inventor(s): Tara Sealy, Ute Stroeher, Stuart Nichol, Jonathan Towner
Keywords(s): 7, Acid, antibodies, ANTIGENS, assay, DETECTING, Detection, Ebola, Ebolavirus, ELISA, Enzyme, Identification, immunosorbent, LINKED, Listed LPM Kirby as of 4/15/2015, Mab, monoclonal, Mouse, NCEZID, NCEZID-DHCPP, Nucleic, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PRIMERS, Probes, Species, Used, virus, Viruses, Zaire
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Detection and Differentiation of Pathogenic Fungi in Clinical Samples Using a Multi-Analyte Profiling System
This invention provides a rapid, sensitive and specific diagnostic tool for the detection of pathogenic fungi and subsequent species-specific discrimination. CDC scientists have developed nucleic acid probes to identify the six most medically important Candida species and endemic mycoses, and to differentiate them from other medically important fungi...
Published: 10/28/2024   |   Inventor(s): Sanchita Das, Teresa Brown, Brian Holloway, Christine Morrison
Keywords(s): Bead, Beads, CANDIDA, CDC Docket Import, CDC Docket Import CDC Prosecuting, Clinical, Clinical SAMPLE, Compositions, DA1XXX, DAXXXX, Detection, Diagnose, Diagnosis, diagnostic, Diagnostic assay, Discriminate, discrimination, DXXXXX, FUNGAL, FUNGI, fungus, Methods, microarray, Nucleic, nucleic acid, OID-NCEZID-DFWED, PATHOGEN, PATHOGENIC, Probe, Species, VKXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XEXXXX, XHXXXX, YAXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Occupational Safety and Health, Application > Diagnostics, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Infectious Disease, ResearchProducts > Research Equipment
Nucleic Acid-based Compositions and Methods for the Species-Specific Detection of Pathogenic Candida Fungi
This invention pertains to the development of oligonucleotides for the rapid nucleic acid-based identification of the Candida fungi species C. haemulonii, C. kefyr, C. lambica, C. lusitaniae, C. norvegensis, C. norvegica, C. rugosa, C. utilis, C. viswanathii, C. zeylanoides, C. dubliniensis, and C. pelliculosa within biological samples. This identification...
Published: 10/28/2024   |   Inventor(s): Cheryl Elie, Christine Morrison, Errol Reiss, Timonthy Lott
Keywords(s): Acid, CANDIDA, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, DETECTING, DXXXXX, Nucleic, OID-NCEZID-DFWED, Probes, Species, VKXXXX, VOXXXX, VPXXXX, WBXXXX, WCXXXX, WIXXXX, XCXXXX, XEXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, Application > Occupational Safety and Health, TherapeuticArea > Dental, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology
Nucleic Acid Assays for the Detection and Discrimination of Aspergillus Fungi Species within Biological Samples
This invention relates to assays for the detection and species-specific identification of Aspergillus fungi. Accurate clinical diagnosis of Aspergillus species has become increasingly important as certain species, such as A. terreus and A. fumigatus, are resistant to specific commonly employed antifungal compounds. Most contemporary fungal diagnostic...
Published: 10/28/2024   |   Inventor(s): Hans Hinrikson, Christine Morrison
Keywords(s): Aspergillus, CDC Docket Import, CDC Docket Import CDC Prosecuting, DAXXXX, DXXXXX, Identification, Molecular, OID-NCEZID-DFWED, Species, VKXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XCXXXX, XEXXXX, XHXXXX, XIXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Occupational Safety and Health, ResearchProducts > Research Equipment, Application > Research Materials, TherapeuticArea > Endocrinology, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease
Species-specific Nucleic Acid Detection Assay for Fungi
This invention pertains to nucleic acid-based assays for the detection of Aspergillus and other filamentous fungi. Assays cover the species-specific detection and diagnosis of infection by Aspergillus, Fusarium, Mucor, Penecillium, Rhizomucor, Absidia, Cunninghamella, Pseudallescheria or Sporthrix in a subject. This can reduce identification time from...
Published: 10/28/2024   |   Inventor(s): Errol Reiss, Lilianna Aidorevich, Jong Soo Choi, Christine Morrison
Keywords(s): Acids, Aspergillus, CANDIDA, CANDIDA ALBICANS, candidiasis, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA1XXX, DAXXXX, DETECTING, Detection, diagnostic, discrimination, DXXXXX, FUNGAL, FUNGI, fungus, I-016-96, I-016-96/0, Mold, Molds, Nucleic, nucleic acid, NUCLEIC ACID DETECTION, OID-NCEZID-DFWED, PCR, PCR ASSAY, PRIMERS, Species, VKXXXX, VPXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, XEXXXX, XHXXXX, XIXXXX, YBXXXX
Category(s): Collaboration Sought > Licensing, ResearchProducts > Research Equipment, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, TherapeuticArea > Ophthalmology, Application > Occupational Safety and Health, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology
Real-time PCR Assays for Selective Detection and Differentiation of B. pertussis, B. parapertussis and B. homesii
CDC researchers developed a real-time PCR assay targeting insertion sequence (IS481) and pertussis toxin subunit 1 (ptxS1) of Bordetella pertussis. This real-time nucleic acid assay offers rapid, sensitive, and quantitative results. The employed primers have been validated through extensive diagnostic testing of 41 Bordetella and 64 non-Bordetella...
Published: 10/28/2024   |   Inventor(s): Kansas Sparks, Maria-Lucia Tondella, Kathleen Tatti
Keywords(s): BORDETELLA, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, Detection, DXXXXX, SELECTIVE, Species
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Diagnostics
Signatures of Genetic Control in Digestive and Liver Disorders
Our technology describes unique genetic signatures in patients with digestive diseases and liver disorders. Using comprehensive analysis of 735 microRNAs and 19,000 mRNAs, we have identified a unique set of microRNAs and/or mRNAs which predict disease phenotypes in patients with digestive and liver disorders. The identification of such point-of- care...
Published: 10/28/2024   |   Inventor(s): Ralph Peace, Nicolaas Fourie, Sarah Abey, Wendy Henderson
Keywords(s): Acid, Altered, CAXXXX, CXXXXX, Digestive, DISORDERS, Expressions, IA3XXX, IAXXXX, IB3XXX, IBXXXX, Identification, IXXXXX, Listed LPM Vepa as of 4/15/2015, liver, MESSENGER, MICRO, miRNA, PHENOTYPE, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Ribonucleic, RNA, Species, THERAPY
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Oncology