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Drug Screening System for Cardioprotection
Application A high throughput screening assay for developing therapies to protect from drug and alcohol-induced cardiotoxicity. Key Benefits A cardiovascular stem-cell-based screening assay that can identify drugs that protect the heart from toxic medications and alcohol. Preliminary data in the laboratory show the system is clinically relevant...
Published: 12/4/2024   |   Inventor(s): Chunhui Xu, Antonio Rampoldi, Yuhong Du
Keywords(s): Assay, Cardiovascular
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery
CFTR Modulators for Treating Rare Forms of Cystic Fibrosis
Application Small molecules to treat cystic fibrosis and other pulmonary diseases. Key Benefits Rescue rare variants of CFTR gene. Serve as PDE4 inhibitors with strong anti-inflammatory effects. Market Summary Cystic fibrosis (CF) is a progressive, genetic disorder that arises from mutations in the cystic fibrosis transmembrane conductance...
Published: 12/4/2024   |   Inventor(s): Eric J. Sorscher, Jeong Hong, Haian Fu, Yuhong Du, Huw Davies, Andras Rab, Candela Manfredi, Xun Yang, Zhi Ren
Keywords(s): Rare/Orphan Diseases, Respiratory, Small Molecule
Category(s): TechPub Algolia > Therapeutics
ComprehENotes: Assessing patients' comprehension of their medical conditions and treatment
Many medical patients are now able to directly access their electronic health records (EHR). Providing such direct access has been shown to lead to improved healthcare outcomes through the patient’s enhanced understanding of their medical conditions and treatment. However, EHR contain medical jargon that challenge populations with lower health...
Published: 6/26/2023   |   Inventor(s): John Lalor, Hao Wu, Li Chen, Kathleen Mazor, Hong Yu
Keywords(s):  
Category(s): Healthcare, Research tools