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Application A small molecule showing cardioprotection from drug-induced and alcohol-induced cytotoxicity. Key Benefits Demonstrates broad impact with cardioprotective effects against multiple cardiotoxic agents, including alcohol and chemotherapeutic drugs like doxorubicin and bortezomib. Does not interfere with the proteasome inhibition activity...

Published: 12/5/2025 | Inventor(s): Chunhui Xu, Antonio Rampoldi, Yuhong Du

Keywords(s): Cardiology and Vascular Devices, Screening Assays, Small Molecule

Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery

CFTR Modulators for Treating Rare Forms of Cystic Fibrosis

Application Small molecules to treat cystic fibrosis and other pulmonary diseases. Key Benefits Rescue rare variants of CFTR gene. Serve as PDE4 inhibitors with strong anti-inflammatory effects. Market Summary Cystic fibrosis (CF) is a progressive, genetic disorder that arises from mutations in the cystic fibrosis transmembrane conductance...

Published: 12/5/2025 | Inventor(s): Eric J. Sorscher, Jeong Hong, Haian Fu, Yuhong Du, Huw Davies, Andras Rab, Candela Manfredi, Xun Yang, Zhi Ren

Keywords(s): Rare and Orphan Disease Treatments, Respiratory Treatments, Small Molecule

Category(s): TechPub Algolia > Therapeutics

ComprehENotes: Assessing patients' comprehension of their medical conditions and treatment

Many medical patients are now able to directly access their electronic health records (EHR). Providing such direct access has been shown to lead to improved healthcare outcomes through the patient’s enhanced understanding of their medical conditions and treatment. However, EHR contain medical jargon that challenge populations with lower health...

Published: 6/26/2023 | Inventor(s): John Lalor, Hao Wu, Li Chen, Kathleen Mazor, Hong Yu

Keywords(s):

Category(s): Healthcare, Research tools