Search Results - chunhui+xu

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Drug Screening System for Cardioprotection
Application A high throughput screening assay for developing therapies to protect from drug and alcohol-induced cardiotoxicity. Key Benefits A cardiovascular stem-cell-based screening assay that can identify drugs that protect the heart from toxic medications and alcohol. Preliminary data in the laboratory show the system is clinically relevant...
Published: 10/17/2024   |   Inventor(s): Chunhui Xu, Antonio Rampoldi, Yuhong Du
Keywords(s): Assay, Cardiovascular
Category(s): TechPub Algolia > Therapeutics, TechPub Algolia > Drug Discovery
Mitigation of Negative Effects of Melphalan on Cardiomyocytes with N-acetyl-L-cysteine (NAC) Treatment
­ Application NAC (N-acetyl-L-cystine) as an antioxidant to reduce chemotherapy induced oxidative stress and cardiotoxicity. Key Benefits Mitigates cardiotoxic side effects of alkylating agent, melphalan in human cardiomyocytes. Market Summary Melphalan is a chemotherapeutic commonly used to treat various cancers including multiple myeloma,...
Published: 7/30/2024   |   Inventor(s): Chunhui Xu, Anant Mandawat, Rui Liu
Keywords(s): Cardiovascular
Category(s): TechPub Algolia > Drug Discovery
Tool for Measuring Cell Purity and Quality Control of Stem Cell-based Products
Application Cell-based assay for sensitive and specific detection of undifferentiated cells in stem cell-related research and development. Key Benefits Nanotechnology-based assay can detect residual undifferentiated cells and characterize cultures that may be tumorigenic. Technology is potentially more sensitive method compared to current methods. Market...
Published: 7/30/2024   |   Inventor(s): Chunhui Xu, Shuming Nie, Ximei Qian, Jingjia Han
Keywords(s): Assay, Cell/Gene Therapy, Regenerative Medicine
Category(s): TechPub Algolia > Diagnostics, TechPub Algolia > Research Tools