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ID
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Method for Repurposing FDA-approved Therapeuti
c
s & Composition for Treating Mesothelioma
The amount of time and money that goes into getting a drug from initial dis
c
overy to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/8/2025
|
Inventor(s):
C
hris Plaisier
,
Sierra Wilferd
,
C
houng Hoang
Keywords(s):
C
ancer
,
Drug
,
Drug Dis
c
overy
Category(s):
Pharma
c
euticals
,
C
ancer
,
C
ancer Therapeutics
,
Artifi
c
ial Intelligence/Machine Learning
,
C
omputing & Information Technology
,
Life S
c
ience (All LS Techs)
Modified Simmons
C
atheter
Neurointerventions with improved su
c
cess Invention Summary: The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 1/8/2025
|
Inventor(s):
Amit Singla
Keywords(s):
Neurologi
c
al disorder & neuropathic pain
Category(s):
Te
c
hnology Classifications > Diagnostics
,
Te
c
hnology Classifications > Healthcare & Life Sciences
,
Te
c
hnology Classifications > Medical Devices
Antiba
c
terial Coagulating Gel Spray
Blood loss and infe
c
tions are a major cause of concern and death for traumatic injuries and wounds. It is estimated that blood loss accounts for more than 35% of all prehospital deaths in trauma patients. Thus, it is imperative that bleeding is stopped quickly and at the point of care. While there are many products to staunch bleeding, including gauze...
Published: 1/8/2025
|
Inventor(s):
Emily Byrne
,
Gra
c
e Billingsley
,
Tran Nguyen
,
Alfonso Gomez-De Leon
,
Os
c
ar Voeller
,
Sarah Stabenfeldt
,
Jessi
c
a Weaver
Keywords(s):
Category(s):
Advan
c
ed Materials/Nanotechnology
,
Biomaterials
,
Life S
c
ience (All LS Techs)
,
Medi
c
al Devices
Sele
c
tive Modulators of Ah-R to Treat Cancer
Synergisti
c
compositions and method of using modulators of Ah-R activity and synergistic compounds to treat cancer Background Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. When activated by the binding of a wide range of both endogenous and exogenous small molecules, AhR signaling influences cellular outcomes in different...
Published: 1/8/2025
|
Inventor(s):
Siva Kolluri
,
Ba
c
h Nguyen
,
Daniel Elson
Keywords(s):
Category(s):
Therapeuti
c
s
Pharma
c
eutical manufacturing of the future: a continuous 3D printing approach for personalized medicine
Ba
c
kground Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharmaceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 1/8/2025
|
Inventor(s):
Mohammed Maniruzzaman
,
Vineet Kulkarni
,
Faez Alkadi
Keywords(s):
Category(s):
Life s
c
iences > Therapeutics > Manufacturing platform
Laser apparatus for mi
c
ro-volume tissue excision
This te
c
hnology uses a laser to remove tiny pieces of tissue for analysis. The laser is shaped into a ring and can be combined with cooling techniques to minimize damage. Background The traditional histopathology workflow, while considered the gold standard for tissue diagnosis, suffers from several limitations. These include the invasiveness of biopsies,...
Published: 1/8/2025
|
Inventor(s):
Thomas Milner
,
James Tunnell
,
Jason King
,
Nitesh Katta
Keywords(s):
Category(s):
Life s
c
iences > Medical technology > Medical devices
,
Life s
c
iences > Medical technology
Highly sensitive pressure sensor for diverse appli
c
ations
A flexible, highly sensitive pressure sensor
c
ombines resistive and capacitive elements using a porous carbon nanotube–Eco flex material. It accurately detects a wide range of pressures, is easy to fabricate, and suits diverse applications like medical monitoring and environmental sensing. Background Pressure sensing technology plays a crucial...
Published: 1/8/2025
|
Inventor(s):
Nanshu Lu
,
Kyoung-Ho Ha
Keywords(s):
Category(s):
Life s
c
iences > Medical technology
Autonomous Brain Ma
c
hine Interface
An advan
c
ed system that enables patients to better control prosthetic devices. Background: Many pathologies lead to loss of the ability to use one or more limbs. Historically, the lost or damaged limb is replaced with a prosthetic device. In recent years prosthetic technology has been developed to enable the control of these devices via a neural signal...
Published: 1/7/2025
|
Inventor(s):
Joseph Fran
c
is
,
Venkata S. Aditya Tarigoppula
,
Brandi Marsh
Keywords(s):
Category(s):
C
ampus > SUNY Downstate Health Sciences University
,
Te
c
hnology Classifications > Computers
Intramedullary Temporomandibular Joint (TMJ) Implant
A novel TMJ implant that redu
c
es stress and strain on the patient. Background: The temporomandibular joint (TMJ) is involved in functions such as chewing, swallowing, and speaking. Degenerative disorders of the TMJ are typically treated with anti-inflammatory drugs. However, once the TMJ has been compromised, surgical treatment is commonly performed....
Published: 1/7/2025
|
Inventor(s):
Martin Pendola
Keywords(s):
Category(s):
C
ampus > SUNY Downstate Health Sciences University
,
Te
c
hnology Classifications > Medical Devices
C
ancer treatment through hTERT inhibition
Title:
C
ancer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025
|
Inventor(s):
Lauren
c
e Hurley
,
Vijay Gokhale
,
HyunJin Kang
,
Kui Wu
Keywords(s):
Category(s):
Te
c
hnology Classifications > Healthcare Portfolios > Oncology
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