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17139
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Title
ID
Descending
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Non-invasive Diagnosti
c
for Meningiomas
Appli
c
ation A non-invasive molecular diagnostic tool that reliably predicts the tumor characteristics and risk of recurrence of meningiomas. Key Benefits Combines meningioma gene expression data, construction of a gene interaction network, and tumor histology data to diagnose and predict clinical outcomes. Complete analytical handling from specimen...
Published: 1/28/2026
|
Inventor(s):
Ali Alawieh
,
Youssef Ismail
,
Tomas Garzon-Muvdi
Keywords(s):
Algorithm, AI, and Ma
c
hine Learning
,
Biomarkers
,
On
c
ology Treatments
,
Personalized Medi
c
ine
,
Platform
,
S
c
reening Assays
Category(s):
Te
c
hPub Algolia > Diagnostics
Sulfonyl-triazole a
c
tivators for cell-selective glycolysis enhancement in cancer and Parkinson’s disease
Ba
c
kground Cellular metabolism is a central regulator of immune cell function and neuronal survival, making it a promising therapeutic target in both cancer and neurodegenerative disease. In solid tumors, tumor-infiltrating lymphocytes (TILs) frequently succumb to metabolic exhaustion due to the nutrient-depleted and immunosuppressive microenvironment,...
Published: 1/27/2026
|
Inventor(s):
Ku-Lung Hsu
,
Xiaoding Jiang
,
Xiaolu
C
ambronne
Keywords(s):
Category(s):
Life s
c
iences > Therapeutics > Formulation
,
Life s
c
iences > Therapeutics > Drug discovery
Mi
c
roneedle array coating technology for enhanced stability and targeted delivery of mRNA and biologics
A mi
c
roneedle-based system uses cryogenically pre-cooled needles coated via thin-film freeze-coating to preserve mRNA stability, enabling efficient, multi-therapeutic intradermal delivery of temperature-sensitive drugs. Background The field of advanced drug delivery systems has grown substantially as the biomedical industry grapples with the complexities...
Published: 1/27/2026
|
Inventor(s):
Zhengrong
C
ui
,
Mi
c
hael Sandoval
,
Robert Williams
,
Drew Weissman
,
Qin Li
Keywords(s):
Category(s):
Life s
c
iences > Therapeutics > Drug discovery
A mi
c
roneedle-based resonant sensor system for continuous, wireless monitoring of wound and physiological states
This te
c
hnology uses gold-coated microneedles and wireless sensors to directly sample wound fluid, detecting infection and other changes in real time. Data is analyzed with machine learning and sent to clinicians for early, continuous wound monitoring. Background Wound monitoring is a critical aspect of healthcare, especially for patients recovering...
Published: 1/27/2026
|
Inventor(s):
James
C
larke
,
Miles Massidda
,
Joseph S
c
hmidt
,
C
ristina Checka
,
S
c
ott Alpard
Keywords(s):
Category(s):
Life s
c
iences > Medical technology > Medical devices
Misalignment Resilient Diffra
c
tive Optical Networks (Case No. 2020-885)
Summary: U
C
LA researchers in the Department of Electrical and Computer Engineering have developed and experimentally validated a comprehensive training scheme that greatly enhances the robustness of diffractive networks to 3D misalignments and fabrication tolerances in their physical implementation. Background: As an optical machine learning framework,...
Published: 1/28/2026
|
Inventor(s):
Aydogan Oz
c
an
Keywords(s):
Opti
c
al Communication
,
Opti
c
al computing
,
opti
c
al implementation
,
Opti
c
al networks
,
opti
c
al processor
Category(s):
Software & Algorithms
,
Software & Algorithms > Image Pro
c
essing
,
Opti
c
s & Photonics
Antibody
c
ompositions for improving detection and treatment of
Bacillus anthracis
infections
This te
c
hnology uses specially designed antibodies with enhanced ability to detect or treat Bacillus anthracis infections, improving both diagnosis and therapy for anthrax. Background Bacillus anthracis, the causative agent of anthrax, is a highly virulent bacterium that poses significant threats to both public health and national security. Anthrax...
Published: 1/27/2026
|
Inventor(s):
George Georgiou
,
Brent Iverson
,
Barrett Harvey
Keywords(s):
Category(s):
Life s
c
iences > Immunology
,
Life s
c
iences > Therapeutics
Engineered enzyme therapy for targeted redu
c
tion of plasma homocysteine in metabolic disorders
This te
c
hnology is a specially engineered human enzyme, modified and PEGylated to break down excess homocysteine in the blood, offering a new treatment for homocystinuria and hyperhomocysteinemia with improved effectiveness and dosing flexibility. Background Homocystinuria and hyperhomocysteinemia are metabolic disorders characterized by elevated...
Published: 1/27/2026
|
Inventor(s):
S
c
ott Rowlinson
,
C
hristopher Daige
,
Leslie Sloan
Keywords(s):
Category(s):
Life s
c
iences > Therapeutics > Small molecule
Regulated Gene Expression During Differentiation of Mature T
C
ells (UCLA Case No. 2022-147)
U
C
LA researchers from the Department of Pathology & Laboratory Medicine have developed a process to genetically modify stem cells to express transgenes in a regulated, stage-specific manner, avoiding the negative consequences of transgene expression during T cell development. Contact UCLA Technology Development Group for more information.
Published: 1/27/2026
|
Inventor(s):
Gay
C
rooks
,
Donald Kohn
Keywords(s):
Category(s):
Therapeuti
c
s > Gene Therapy And Editing
,
Therapeuti
c
s > Stem Cells And Regenerative Medicine
,
Therapeuti
c
s > Oncology
,
Therapeuti
c
s > Immunology And Immunotherapy
,
Therapeuti
c
s > Inflammation And Inflammatory Diseases
Enhan
c
ing T Cell Production in Vitro From Stem and Progenitor Cells (UCLA Case No. 2022-257)
U
C
LA researchers from the Department of Pathology and Laboratory Medicine have developed an innovative differentiation method to increase T cell production for T cell immunotherapy. Contact UCLA Technology Development Group for more information.
Published: 1/27/2026
|
Inventor(s):
Gay
C
rooks
,
C
hristopher Seet
Keywords(s):
Category(s):
Therapeuti
c
s > Oncology
,
Therapeuti
c
s > Immunology And Immunotherapy
Insulin
C
rystals Removal Platform
Des
c
ription: A platform technology for improving insulin delivery by removing insulin-derived fibrils through polyester membrane filtration. This invention employs membrane filters integrated into insulin delivery systems to selectively remove insulin-derived fibrils (IDFs) from insulin formulations. By filtering out fibrils while preserving active...
Published: 1/27/2026
|
Inventor(s):
Ulrike Klueh
Keywords(s):
Category(s):
Te
c
hnology Category > Biomedical
,
Te
c
hnology Category > Devices
,
Te
c
hnology Category > Drug Delivery
,
Te
c
hnology Category > Life Science
,
Te
c
hnology Category > Medical Devices
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