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ID
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Method of Treating Obesity-Indu
c
ed Glucose Intolerance and Liver Fibrosis (UCLA Case No. 2021-323)
U
C
LA researchers in the School of Engineering have discovered a novel method to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...
Published: 9/24/2024
|
Inventor(s):
Zhen Gu
Keywords(s):
glu
c
ose intolerance
,
liver fibrosis
,
Nanoparti
c
les
,
Not
c
h signaling pathway
,
obesity
Category(s):
Therapeuti
c
s > Metabolism And Endocrinology
SELE
C
TIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES
SELE
C
TIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a novel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
Ree
c
e Akana
Keywords(s):
C
ancer
,
Immuno-On
c
ology
,
T-
C
ell Activation
Category(s):
Te
c
hnology Classifications > Biology
C
OMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
C
OMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a novel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
C
harles Chan
,
Thomas Ambrosi
,
Irving Weissman
,
Mi
c
hael Longaker
,
Rahul Sinha
,
Debashis Sahoo
Keywords(s):
Hydrogel
,
Stem
C
ell
Category(s):
Te
c
hnology Classifications > Biology
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VA
C
CINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VA
C
CINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed novel universal vaccine candidates for H5 influenza viruses. Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Duo Xu
,
Peter Kim
Keywords(s):
Immunofo
c
using
,
Va
c
cine
Category(s):
Te
c
hnology Classifications > Biology
NOVEL SMALL MOLE
C
ULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
NOVEL SMALL MOLE
C
ULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
|
Inventor(s):
Evan Obrien
,
Kaavya Kumar
,
Brian Kobilka
,
Susruta Majumdar
,
Vipin Rangari
Keywords(s):
Opiod
,
Pain
Category(s):
Te
c
hnology Classifications > Chemistry
C
41 Analogs
This invention relates generally to neurodegenerative diseases and
c
onditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
Wei Wang
,
Rui
C
hang
,
Vijayan Rama
c
handran
,
Patri
c
k Ronaldson
Keywords(s):
Category(s):
Te
c
hnology Classifications > Healthcare Portfolios > Neurology
,
Te
c
hnology Classifications > Life Sciences > Nutraceuticals
,
Te
c
hnology Classifications > Life Sciences > Small Molecules
,
Te
c
hnology Classifications > Life Sciences > Therapeutics
,
Te
c
hnology Classifications > Life Sciences > Biologics
Stimulation Devi
c
e to treat Hand Weakness from Stroke or Spinal Injury
A growing number of people experien
c
e hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and non-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atharva Wani
,
Niteesh Nigam
,
Onkar
C
havan
,
Yash Bellap
,
Joelly Lobato
,
Ishan Swanand Vyas
,
Suhrud Parag Joglekar
Keywords(s):
Category(s):
Life S
c
ience (All LS Techs)
,
Medi
c
al Devices
,
Manufa
c
turing/Construction/Mechanical
Vital Signs Monitoring using Depth
C
ameras
C
ardiovascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024
|
Inventor(s):
Yu Rong
,
Daniel Bliss
Keywords(s):
Category(s):
C
omputing & Information Technology
,
Medi
c
al Devices
,
Life S
c
ience (All LS Techs)
,
Medi
c
al Diagnostics/Sensors
,
Medi
c
al Imaging
Head Motion
C
orrection with Soft Pressure Pad for MRI Scans
Addressed Need Head motion remains a major
c
hallenge during medical imaging scans, particularly in pediatric and older patient populations. Motion impacts diagnostic image quality, costing both time and money in the clinical setting. In research, motion artifacts can introduce errors into quantitative measurements, especially in high-resolution or...
Published: 9/24/2024
|
Inventor(s):
Keywords(s):
Category(s):
Medi
c
al Devices
,
Medi
c
al Imaging
Inhibitors of the N-terminal Domain of the Androgen Re
c
eptor (UCLA Case No. 2023-075)
Resear
c
hers at UCLA under the guidance of Drs. Matthew Rettig and Michael Jung have developed novel molecular compounds that reduce growth of prostate cancer cells. Dr. Jung in collaboration with Dr. Rettig have furthered the development of these compounds by synthesizing a new series of analogues that have similar inhibitory effects. BACKGROUND: Prostate...
Published: 9/23/2024
|
Inventor(s):
Matthew Rettig
,
Mi
c
hael Jung
Keywords(s):
androgen re
c
eptor therapy
,
c
astration resistant prostate cancer
,
On
c
ology
,
On
c
ology (Small Molecules, Peptides and Antibodies)
,
prostate
c
ancer
,
small mole
c
ules
Category(s):
Therapeuti
c
s > Oncology
,
Therapeuti
c
s > Oncology > Oncology (Small Molecules)
1
2
3
4
5
6
7
8
9
10
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