Search Results - byungjin+hwang

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Inhibition of T Cell Differentiation and Senescence by Overexpression of Transcription Factor c-Myb
Abstract: Adoptive Cell Therapy (ACT) is a promising technique that uses a patient's own T cells to treat cancer. The process requires removing and engineering a patient's T cells to express a chimeric antigen receptor (CAR) or T cell receptor (TCR) that targets a specific cancer antigen. When the modified T cells are reintroduced into the patient,...
Published: 4/8/2024   |   Inventor(s): Sanjivan Gautam, Yun Ji, Luca Gattinoni
Keywords(s): act, Adoptive Cell Transfer, CANCER, CAR, chimeric antigen receptor, Gattinoni, Immunotherapy, Infectious Disease, Stem Cell, T cell, T Cell Receptor, TCR
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing
Overexpression of Phf19 on T Cells Enhances Therapeutic Effects of T Cell-Based Therapies (such as Chimeric Antigen Receptor [CAR] Therapies)
Abstract: T cell-based immunotherapy (such as CAR therapies) is a promising approach for the treatment of several cancers. However, T cells currently employed for various T cell-based immunotherapies are usually senescent and terminally differentiated leading to poor proliferative and survival capacity, limiting their therapeutic effectiveness once...
Published: 4/8/2024   |   Inventor(s): Yun Ji, Luca Gattinoni
Keywords(s): CAR-T Therapy, CD8, chimeric antigen receptor, Gattinoni, Phf19, T cell
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics
Natural Compound for Bitter Taste Masking
Reduces the Bitter Taste of Nutraceuticals and Medications, Improving Their Palatability This naturally occurring anti-bittering compound reduces the bitter taste of certain foods and pharmaceuticals, improving their palatability and consumption. Bitterness is one of the five basic taste modalities. People have strong aversions to bitterness, particularly...
Published: 2/20/2024   |   Inventor(s): Yu Wang, Jinpyo An
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Nutraceutical, Technology Classifications > Others > Others
SCITO-SEQ: SINGLE CELL COMBINATORIAL INDEXED CYTOMETRY SEQUENCING
SCITO-SEQ: SINGLE CELL COMBINATORIAL INDEXED CYTOMETRY SEQUENCING Researchers at UCSF have developed SCITO-seq, a new workflow for single cell sequencing-based proteomics. The use of DNA to barcode and tag antibodies has created new opportunities to use sequencing to profile the molecular properties of thousands of cells simultaneously. Furthermore,...
Published: 1/19/2024   |   Inventor(s): Chun Ye, Byungjin Hwang, David Lee
Keywords(s): Antibody, Droplet-Based Single Cell Sequencing, dsc-Seq, Microfluidics, Proteomics, Single Cell, Single Cell Analysis
Category(s): Technology Classifications > Biology
Silk Wrinkles: Tuning Structural Protein Coformation for Dynamic, Responsive, Multifunctional Micropatterns
PROBLEM Protein micropatterning and nanopatterning have long provided sophisticated strategies for a wide range of applications including biointerfaces, tissue engineering, optics/photonics, and bioelectronics. In recent years, various micro- and nanofabrication technologies have been utilized to transform a water-based suspension of silk protein into...
Published: 9/30/2020   |   Inventor(s): Fiorenzo Omenetto, Yu Wang
Keywords(s):  
Category(s): Biomaterials
Disturbed Self-assembly: Growing Block Copolymer Nanosheet (BCNS) Densely and Naturally
AbstractNanosheet plays an important role in the development of clinical therapeutics and diagnostics e.g., bioimaging/sensing, drug delivery systems and tissue engineering. As one of the most important approaches to preparing nanomaterials, self-assembly is able to give rise to various nanostructures from zero-dimension nanoparticles to three-dimension...
Published: 10/8/2024   |   Inventor(s): Yu Wang, Weihong Zhong
Keywords(s):  
Category(s): Technologies > Next Generation Materials & Technology > Nanotechnology
Functionalized Porous Polymer Nanocomposites via Introducing Functional Components into Emulsion Systems
AbstractFunctional porous polymer films are of great interest to academia as well as industry for a variety of applications, such as gas separation, water purification and sensors. A porous structure can not only reduce the density of the material, but can also remarkably increase the surface/interface area, which can be used for various functionalizations....
Published: 10/8/2024   |   Inventor(s): Yu Wang, Weihong Zhong, Bin Li
Keywords(s):  
Category(s): Technologies > Energy & Environment > Clean Tech
Adhesive Conductive Binder for Battery Electrodes
Abstract Researchers at WSU have developed a high-performance hybrid conductive adhesives (HCA), which showed strong adhesion properties, high ionic and electric conductivities and good elasticity.Energy storage devices are in desperate need of high-performance binder materials that can maintain good/stable contact among all the components and at the...
Published: 10/8/2024   |   Inventor(s): Yu Wang, Weihong Zhong
Keywords(s):  
Category(s): Technologies > Energy & Environment > Clean Tech, Technologies > Next Generation Materials & Technology > Advanced Materials, Technologies > Energy & Environment > Electrical/Electronics, Technologies > Energy & Environment > Energy
Protein-based Nanofabrics as Multi-functional “Green” Air Filtering Materials for High Efficiency Particulate and Toxic Chemical Filtration
AbstractAir filters currently in the market cannot simultaneously purify the air from particles and chemicals effectively. The non-degradable synthetic nature of existing products also creates environmental issues. To solve these problems, researchers at Washington State University have developed a green multi-functional air filter. This filter is...
Published: 10/8/2024   |   Inventor(s): Weihong Zhong, Hamid Souzandeh, Yu Wang
Keywords(s):  
Category(s): Technologies > Energy & Environment > Clean Tech, Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Global Human and Animal Health
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 4/19/2023   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging
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